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Entry version 62 (12 Aug 2020)
Sequence version 1 (09 Jul 2014)
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Protein

Potassium-transporting ATPase KdpC subunit

Gene

kdpC

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseImported
Biological processIon transport, Potassium transportUniRule annotationARBA annotation, Transport
LigandATP-bindingUniRule annotationARBA annotation, Nucleotide-binding, Potassium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Potassium-transporting ATPase KdpC subunitUniRule annotation
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] C chainUniRule annotation
Potassium-binding and translocating subunit CUniRule annotation
Potassium-translocating ATPase C chainUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:kdpCUniRule annotationImported
ORF Names:DSI38_18155Imported, ERS007661_00943Imported, ERS007663_00448Imported, ERS007665_01314Imported, ERS007670_00152Imported, ERS013471_01443Imported, ERS023446_01732Imported, ERS027659_03126Imported, ERS075361_03185Imported, ERS094182_03358Imported, F6W99_03735Imported, F9908_17555Imported, FRD82_01285Imported, SAMEA2683035_03090Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000321489 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000256245 Componenti: Unassembled WGS sequence
  • UP000041288 Componenti: Unassembled WGS sequence
  • UP000039217 Componenti: Unassembled WGS sequence
  • UP000431688 Componenti: Unassembled WGS sequence
  • UP000047893 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000042440 Componenti: Unassembled WGS sequence
  • UP000326088 Componenti: Chromosome
  • UP000046213 Componenti: Unassembled WGS sequence
  • UP000045274 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence
  • UP000050164 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationARBA annotation, Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC.

UniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the KdpC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationARBA annotation

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_00276, KdpC, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003820, KdpC

The PANTHER Classification System

More...
PANTHERi
PTHR30042, PTHR30042, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02669, KdpC, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF001296, K_ATPase_KdpC, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00681, kdpC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A045H6S5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRQLLPALT MLLVFTVITG IVYPLAVTGV GQLFFGDQAN GALLERDGQV
60 70 80 90 100
IGSAHIGQQF TAAKYFHPRP SSAGDGYDAA ASSGSNLGPT NEKLLAAVAE
110 120 130 140 150
RVTAYRKENN LPADTLVPVD AVTGSGSGLD PAISVVNAKL QAPRVAQARN
160 170 180
ISIRQVERLI EDHTDARGLG FLGERAVNVL RLNLALDRL
Length:189
Mass (Da):20,028
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBD09E458DBE7E214
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CNFT01000853 Genomic DNA Translation: CKS45621.1
CQAC01000028 Genomic DNA Translation: CNH07891.1
CQGE01000030 Genomic DNA Translation: CNM96516.1
CQPL01000017 Genomic DNA Translation: CNT77646.1
CQPV01000041 Genomic DNA Translation: CNU07880.1
CQPW01000202 Genomic DNA Translation: CNU57403.1
CQQC01000220 Genomic DNA Translation: CNU61889.1
CQTT01000028 Genomic DNA Translation: CNY38892.1
CVKR01000029 Genomic DNA Translation: CRF27887.1
WFKV01000024 Genomic DNA Translation: KAB7800166.1
CP044345 Genomic DNA Translation: QEX92915.1
QSXJ01001044 Genomic DNA Translation: REM63215.1
FPTZ01000025 Genomic DNA Translation: SGI21561.1
VOOQ01000021 Genomic DNA Translation: TXB95157.1

NCBI Reference Sequences

More...
RefSeqi
WP_003405322.1, NZ_WUJD01000009.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMC45377; AMC45377; RN05_1101
CKR75459; CKR75459; ERS027654_02163
CKS45621; CKS45621; ERS027659_03126
CKT04674; CKT04674; ERS027652_03987
CKW66209; CKW66209; ERS031537_04458
CNG90480; CNG90480; ERS124361_02257
CNM96516; CNM96516; ERS023446_01732
CNT77646; CNT77646; ERS007670_00152
CNU07880; CNU07880; ERS007663_00448
CNU57403; CNU57403; ERS007665_01314
CNU61889; CNU61889; ERS007661_00943
CNY38892; CNY38892; ERS013471_01443
COU67782; COU67782; ERS007672_00161
CRH13089; CRH13089; BN1213_02152
CRH13678; CRH13678; BN1303_02234

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23492834

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.211.peg.3336

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CNFT01000853 Genomic DNA Translation: CKS45621.1
CQAC01000028 Genomic DNA Translation: CNH07891.1
CQGE01000030 Genomic DNA Translation: CNM96516.1
CQPL01000017 Genomic DNA Translation: CNT77646.1
CQPV01000041 Genomic DNA Translation: CNU07880.1
CQPW01000202 Genomic DNA Translation: CNU57403.1
CQQC01000220 Genomic DNA Translation: CNU61889.1
CQTT01000028 Genomic DNA Translation: CNY38892.1
CVKR01000029 Genomic DNA Translation: CRF27887.1
WFKV01000024 Genomic DNA Translation: KAB7800166.1
CP044345 Genomic DNA Translation: QEX92915.1
QSXJ01001044 Genomic DNA Translation: REM63215.1
FPTZ01000025 Genomic DNA Translation: SGI21561.1
VOOQ01000021 Genomic DNA Translation: TXB95157.1
RefSeqiWP_003405322.1, NZ_WUJD01000009.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC45377; AMC45377; RN05_1101
CKR75459; CKR75459; ERS027654_02163
CKS45621; CKS45621; ERS027659_03126
CKT04674; CKT04674; ERS027652_03987
CKW66209; CKW66209; ERS031537_04458
CNG90480; CNG90480; ERS124361_02257
CNM96516; CNM96516; ERS023446_01732
CNT77646; CNT77646; ERS007670_00152
CNU07880; CNU07880; ERS007663_00448
CNU57403; CNU57403; ERS007665_01314
CNU61889; CNU61889; ERS007661_00943
CNY38892; CNY38892; ERS013471_01443
COU67782; COU67782; ERS007672_00161
CRH13089; CRH13089; BN1213_02152
CRH13678; CRH13678; BN1303_02234
GeneIDi23492834
PATRICifig|1773.211.peg.3336

Family and domain databases

HAMAPiMF_00276, KdpC, 1 hit
InterProiView protein in InterPro
IPR003820, KdpC
PANTHERiPTHR30042, PTHR30042, 1 hit
PfamiView protein in Pfam
PF02669, KdpC, 1 hit
PIRSFiPIRSF001296, K_ATPase_KdpC, 1 hit
TIGRFAMsiTIGR00681, kdpC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A045H6S5_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A045H6S5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: August 12, 2020
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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