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Protein

Protein RecA

Gene

recA

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi67 – 74ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, HydrolaseImported
Biological processDNA damage, DNA recombinationUniRule annotationSAAS annotation, DNA repairUniRule annotation, SOS responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotationImported
Synonyms:recA_1Imported
ORF Names:ERS007663_00628Imported, ERS007665_01758Imported, ERS007670_02085Imported, ERS007672_01842Imported, ERS007679_03054Imported, ERS007681_02594Imported, ERS007703_03431Imported, ERS007720_02931Imported, ERS007722_03836Imported, ERS007741_02827Imported, ERS023446_04054Imported, ERS024213_00782Imported, ERS024276_00304Imported, ERS027651_02128Imported, ERS027653_01289Imported, ERS027654_01999Imported, ERS027656_00675Imported, ERS027659_00493Imported, ERS027666_00506Imported, ERS031537_01341Imported, ERS124361_02183Imported, SAMEA2682864_02041Imported, SAMEA2683035_01664Imported
OrganismiMycobacterium tuberculosisImported
Taxonomic identifieri1773 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000049498 Componenti: Unassembled WGS sequence
  • UP000049861 Componenti: Unassembled WGS sequence
  • UP000047075 Componenti: Unassembled WGS sequence
  • UP000045842 Componenti: Unassembled WGS sequence
  • UP000046932 Componenti: Unassembled WGS sequence
  • UP000049989 Componenti: Unassembled WGS sequence
  • UP000041288 Componenti: Unassembled WGS sequence
  • UP000043293 Componenti: Unassembled WGS sequence
  • UP000048600 Componenti: Unassembled WGS sequence
  • UP000183655 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000048289 Componenti: Unassembled WGS sequence
  • UP000049258 Componenti: Unassembled WGS sequence
  • UP000050143 Componenti: Unassembled WGS sequence
  • UP000049139 Componenti: Unassembled WGS sequence
  • UP000038802 Componenti: Unassembled WGS sequence
  • UP000049114 Componenti: Unassembled WGS sequence
  • UP000046213 Componenti: Unassembled WGS sequence
  • UP000045274 Componenti: Unassembled WGS sequence
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000049058 Componenti: Unassembled WGS sequence
  • UP000044938 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 196RECA_2InterPro annotationAdd BLAST160
Domaini201 – 262RECA_3InterPro annotationAdd BLAST62
Domaini366 – 508DOD-type homing endonucleaseInterPro annotationAdd BLAST143
Domaini664 – 714RECA_3InterPro annotationAdd BLAST51
Domaini670 – 692INTEIN_C_TERInterPro annotationAdd BLAST23

Sequence similaritiesi

Belongs to the RecA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00983 recA, 1 hit
Gene3Di3.10.28.10, 1 hit
3.30.250.10, 1 hit
HAMAPiMF_00268 RecA, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR003586 Hint_dom_C
IPR003587 Hint_dom_N
IPR036844 Hint_dom_sf
IPR027434 Homing_endonucl
IPR006142 INTEIN
IPR030934 Intein_C
IPR004042 Intein_endonuc
IPR006141 Intein_N
IPR004860 LAGLIDADG_2
IPR027417 P-loop_NTPase
IPR020588 RecA_ATP-bd
IPR023400 RecA_C
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF14528 LAGLIDADG_3, 1 hit
PF00154 RecA, 1 hit
PRINTSiPR00379 INTEIN
PR00142 RECA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00305 HintC, 1 hit
SM00306 HintN, 1 hit
SUPFAMiSSF51294 SSF51294, 2 hits
SSF52540 SSF52540, 1 hit
SSF54752 SSF54752, 1 hit
SSF55608 SSF55608, 1 hit
TIGRFAMsiTIGR01443 intein_Cterm, 1 hit
TIGR01445 intein_Nterm, 1 hit
TIGR02012 tigrfam_recA, 1 hit
PROSITEiView protein in PROSITE
PS50818 INTEIN_C_TER, 1 hit
PS50819 INTEIN_ENDONUCLEASE, 1 hit
PS50817 INTEIN_N_TER, 1 hit
PS00321 RECA_1, 1 hit
PS50162 RECA_2, 1 hit
PS50163 RECA_3, 2 hits

Sequencei

Sequence statusi: Complete.

A0A045GV14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQTPDREKA LELAVAQIEK SYGKGSVMRL GDEARQPISV IPTGSIALDV
60 70 80 90 100
ALGIGGLPRG RVIEIYGPES SGKTTVALHA VANAQAAGGV AAFIDAEHAL
110 120 130 140 150
DPDYAKKLGV DTDSLLVSQP DTGEQALEIA DMLIRSGALD IVVIDSVAAL
160 170 180 190 200
VPRAELEGEM GDSHVGLQAR LMSQALRKMT GALNNSGTTA IFINQLRDKI
210 220 230 240 250
GVMFGSPETT TGGKALKFYA SVRMDVRRVE TLKDGTNAVG NRTRVKVVKN
260 270 280 290 300
KCLAEGTRIF DPVTGTTHRI EDVVDGRKPI HVVAAAKDGT LHARPVVSWF
310 320 330 340 350
DQGTRDVIGL RIAGGAIVWA TPDHKVLTEY GWRAAGELRK GDRVAQPRRF
360 370 380 390 400
DGFGDSAPIP ADHARLLGYL IGDGRDGWVG GKTPINFINV QRALIDDVTR
410 420 430 440 450
IAATLGCAAH PQGRISLAIA HRPGERNGVA DLCQQAGIYG KLAWEKTIPN
460 470 480 490 500
WFFEPDIAAD IVGNLLFGLF ESDGWVSREQ TGALRVGYTT TSEQLAHQIH
510 520 530 540 550
WLLLRFGVGS TVRDYDPTQK RPSIVNGRRI QSKRQVFEVR ISGMDNVTAF
560 570 580 590 600
AESVPMWGPR GAALIQAIPE ATQGRRRGSQ ATYLAAEMTD AVLNYLDERG
610 620 630 640 650
VTAQEAAAMI GVASGDPRGG MKQVLGASRL RRDRVQALAD ALDDKFLHDM
660 670 680 690 700
LAEELRYSVI REVLPTRRAR TFDLEVEELH TLVAEGVVVH NCSPPFKQAE
710 720 730 740 750
FDILYGKGIS REGSLIDMGV DQGLIRKSGA WFTYEGEQLG QGKENARNFL
760 770 780 790
VENADVADEI EKKIKEKLGI GAVVTDDPSN DGVLPAPVDF
Length:790
Mass (Da):85,389
Last modified:July 9, 2014 - v1
Checksum:iAD16340D2ED5E572
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CFOE01000357 Genomic DNA Translation: CFE40660.1
CNCN01000038 Genomic DNA Translation: CKN73931.1
CNDE01000130 Genomic DNA Translation: CKO64452.1
CNFT01000066 Genomic DNA Translation: CKQ98158.1
CNFV01000068 Genomic DNA Translation: CKR14284.1
CNFS01000235 Genomic DNA Translation: CKR42670.1
CNFR01000369 Genomic DNA Translation: CKR67893.1
CNGG01000062 Genomic DNA Translation: CKS08769.1
CIEA01000020 Genomic DNA Translation: CKS09819.1
CNIS01000170 Genomic DNA Translation: CKU82934.1
CHDS01000037 Genomic DNA Translation: CNG88014.1
CQGE01000188 Genomic DNA Translation: CNN60126.1
CQPV01000061 Genomic DNA Translation: CNU16153.1
CQPL01000403 Genomic DNA Translation: CNU82724.1
CQPW01000313 Genomic DNA Translation: CNU86544.1
CHEE01000295 Genomic DNA Translation: COV44581.1
CSAD01000497 Genomic DNA Translation: COW07300.1
CSAE01000465 Genomic DNA Translation: COW33922.1
CSAJ01000422 Genomic DNA Translation: COW60901.1
CHKL01000362 Genomic DNA Translation: COW62573.1
CSAM01000446 Genomic DNA Translation: COW96845.1
FPTZ01000009 Genomic DNA Translation: SGH64617.1
FPXX01000011 Genomic DNA Translation: SGM24437.1
RefSeqiWP_003414006.1, NZ_PYQD01000017.1

Genome annotation databases

EnsemblBacteriaiAMC47189; AMC47189; RN05_2913
CFE40660; CFE40660; ERS007681_02594
CKN73931; CKN73931; ERS024276_00304
CKO64452; CKO64452; ERS024213_00782
CKQ98158; CKQ98158; ERS027659_00493
CKR14284; CKR14284; ERS027656_00675
CKR42670; CKR42670; ERS027653_01289
CKR67893; CKR67893; ERS027654_01999
CKS08769; CKS08769; ERS027666_00506
CKU82934; CKU82934; ERS031537_01341
CNG88014; CNG88014; ERS124361_02183
CNN60126; CNN60126; ERS023446_04054
CNU16153; CNU16153; ERS007663_00628
CNU82724; CNU82724; ERS007670_02085
CNU86544; CNU86544; ERS007665_01758
CNZ22247; CNZ22247; ERS013471_03848
COV44581; COV44581; ERS007672_01842
COW07300; COW07300; ERS007679_03054
COW33922; COW33922; ERS007703_03431
COW60901; COW60901; ERS007720_02931
COW62573; COW62573; ERS007741_02827
COW96845; COW96845; ERS007722_03836
PATRICifig|1773.206.peg.2251

Similar proteinsi

Entry informationi

Entry nameiA0A045GV14_MYCTX
AccessioniPrimary (citable) accession number: A0A045GV14
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: July 18, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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