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Entry version 61 (12 Aug 2020)
Sequence version 1 (09 Jul 2014)
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Protein
Submitted name:

Fatty acyl CoA thioesterase FcoT

Gene

fcoT

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Fatty acyl CoA thioesterase FcoTImported
Submitted name:
Probable fatty acyl CoA thioesterase type III FcoTImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fcoTImported
ORF Names:CAB90_00108Imported, DSI38_24000Imported, E5M52_01255Imported, ERS007657_01867Imported, ERS007670_00407Imported, ERS007679_02774Imported, ERS007681_02918Imported, ERS007688_02272Imported, ERS007720_01865Imported, ERS007722_01989Imported, ERS007741_03447Imported, ERS013471_01805Imported, ERS023446_01577Imported, ERS024276_00099Imported, ERS027646_01193Imported, ERS027659_00691Imported, ERS027661_01029Imported, ERS075361_00728Imported, ERS094182_00190Imported, F6W99_02739Imported, F9908_02815Imported, FRD82_08200Imported, SAMEA2683035_00246Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000321489 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000048948 Componenti: Unassembled WGS sequence
  • UP000256245 Componenti: Unassembled WGS sequence
  • UP000236349 Componenti: Chromosome
  • UP000045842 Componenti: Unassembled WGS sequence
  • UP000297584 Componenti: Unassembled WGS sequence
  • UP000049989 Componenti: Unassembled WGS sequence
  • UP000041288 Componenti: Unassembled WGS sequence
  • UP000431688 Componenti: Unassembled WGS sequence
  • UP000043293 Componenti: Unassembled WGS sequence
  • UP000049023 Componenti: Unassembled WGS sequence
  • UP000048600 Componenti: Unassembled WGS sequence
  • UP000047893 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000046947 Componenti: Unassembled WGS sequence
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000048289 Componenti: Unassembled WGS sequence
  • UP000046680 Componenti: Unassembled WGS sequence
  • UP000042440 Componenti: Unassembled WGS sequence
  • UP000326088 Componenti: Chromosome
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000040993 Componenti: Unassembled WGS sequence
  • UP000044938 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.129.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022598, FcoT_ThioEstase
IPR043064, FcoT_ThioEstase_Rv0098-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10862, FcoT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A045GLC3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHTDLTPCT RVLASSGTVP IAEELLARVL EPYSCKGCRY LIDAQYSATE
60 70 80 90 100
DSVLAYGNFT IGESAYIRST GHFNAVELIL CFNQLAYSAF APAVLNEEIR
110 120 130 140 150
VLRGWSIDDY CQHQLSSMLI RKASSRFRKP LNPQKFSARL LCRDLQVIER
160 170 180
TWRYLKVPCV IEFWDENGGA ASGEIELAAL NIP
Length:183
Mass (Da):20,529
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEC4FCF0B8032355F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP024614 Genomic DNA Translation: AUS49114.1
CFOE01000437 Genomic DNA Translation: CFE41421.1
CFOH01000364 Genomic DNA Translation: CFE53663.1
CGCX01000642 Genomic DNA Translation: CFR80736.1
CNCN01000011 Genomic DNA Translation: CKN65978.1
CNFT01000100 Genomic DNA Translation: CKR08851.1
CNFU01000154 Genomic DNA Translation: CKR32444.1
CNGE01000160 Genomic DNA Translation: CKS06017.1
CQAC01000003 Genomic DNA Translation: CNG19994.1
CQGE01000026 Genomic DNA Translation: CNM90533.1
CQPL01000052 Genomic DNA Translation: CNT88129.1
CQTT01000041 Genomic DNA Translation: CNY50990.1
CSAD01000419 Genomic DNA Translation: COV95445.1
CSAJ01000207 Genomic DNA Translation: COW15852.1
CSAM01000130 Genomic DNA Translation: COW19380.1
CHKL01000522 Genomic DNA Translation: COW92887.1
CVKR01000001 Genomic DNA Translation: CRF24779.1
WFKV01000002 Genomic DNA Translation: KAB7807025.1
CP044345 Genomic DNA Translation: QEX91933.1
QSXJ01001100 Genomic DNA Translation: REM60223.1
FPTZ01000001 Genomic DNA Translation: SGH06274.1
SRLJ01000001 Genomic DNA Translation: TGD83652.1
VOOQ01000196 Genomic DNA Translation: TXB93859.1

NCBI Reference Sequences

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RefSeqi
WP_003899810.1, NZ_WUJD01000002.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AMC44384; AMC44384; RN05_0108
CFE41421; CFE41421; ERS007681_02918
CFE53663; CFE53663; ERS007688_02272
CFR80736; CFR80736; ERS007657_01867
CKN65978; CKN65978; ERS024276_00099
CKO44152; CKO44152; ERS024213_00461
CKQ96940; CKQ96940; ERS027653_00423
CKR08851; CKR08851; ERS027659_00691
CKR31168; CKR31168; ERS027652_01127
CKR32444; CKR32444; ERS027661_01029
CKR40114; CKR40114; ERS027654_01261
CKR51000; CKR51000; ERS027656_01440
CKS06017; CKS06017; ERS027646_01193
CKS13614; CKS13614; ERS027644_02633
CKS25932; CKS25932; ERS027666_00763
CKU53779; CKU53779; ERS031537_00734
CNG74913; CNG74913; ERS124361_01766
CNM90533; CNM90533; ERS023446_01577
CNT88129; CNT88129; ERS007670_00407
CNY50990; CNY50990; ERS013471_01805
COV43775; COV43775; ERS007672_01825
COV95445; COV95445; ERS007679_02774
COW10404; COW10404; ERS007726_00070
COW15852; COW15852; ERS007720_01865
COW19380; COW19380; ERS007722_01989
COW33823; COW33823; ERS007728_00301
COW35714; COW35714; ERS007731_00165
COW82087; COW82087; ERS007739_00141
COW92887; COW92887; ERS007741_03447
CRH09473; CRH09473; BN1213_00194
CRH15702; CRH15702; BN1303_03284

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23493821

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1773.206.peg.3486

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP024614 Genomic DNA Translation: AUS49114.1
CFOE01000437 Genomic DNA Translation: CFE41421.1
CFOH01000364 Genomic DNA Translation: CFE53663.1
CGCX01000642 Genomic DNA Translation: CFR80736.1
CNCN01000011 Genomic DNA Translation: CKN65978.1
CNFT01000100 Genomic DNA Translation: CKR08851.1
CNFU01000154 Genomic DNA Translation: CKR32444.1
CNGE01000160 Genomic DNA Translation: CKS06017.1
CQAC01000003 Genomic DNA Translation: CNG19994.1
CQGE01000026 Genomic DNA Translation: CNM90533.1
CQPL01000052 Genomic DNA Translation: CNT88129.1
CQTT01000041 Genomic DNA Translation: CNY50990.1
CSAD01000419 Genomic DNA Translation: COV95445.1
CSAJ01000207 Genomic DNA Translation: COW15852.1
CSAM01000130 Genomic DNA Translation: COW19380.1
CHKL01000522 Genomic DNA Translation: COW92887.1
CVKR01000001 Genomic DNA Translation: CRF24779.1
WFKV01000002 Genomic DNA Translation: KAB7807025.1
CP044345 Genomic DNA Translation: QEX91933.1
QSXJ01001100 Genomic DNA Translation: REM60223.1
FPTZ01000001 Genomic DNA Translation: SGH06274.1
SRLJ01000001 Genomic DNA Translation: TGD83652.1
VOOQ01000196 Genomic DNA Translation: TXB93859.1
RefSeqiWP_003899810.1, NZ_WUJD01000002.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC44384; AMC44384; RN05_0108
CFE41421; CFE41421; ERS007681_02918
CFE53663; CFE53663; ERS007688_02272
CFR80736; CFR80736; ERS007657_01867
CKN65978; CKN65978; ERS024276_00099
CKO44152; CKO44152; ERS024213_00461
CKQ96940; CKQ96940; ERS027653_00423
CKR08851; CKR08851; ERS027659_00691
CKR31168; CKR31168; ERS027652_01127
CKR32444; CKR32444; ERS027661_01029
CKR40114; CKR40114; ERS027654_01261
CKR51000; CKR51000; ERS027656_01440
CKS06017; CKS06017; ERS027646_01193
CKS13614; CKS13614; ERS027644_02633
CKS25932; CKS25932; ERS027666_00763
CKU53779; CKU53779; ERS031537_00734
CNG74913; CNG74913; ERS124361_01766
CNM90533; CNM90533; ERS023446_01577
CNT88129; CNT88129; ERS007670_00407
CNY50990; CNY50990; ERS013471_01805
COV43775; COV43775; ERS007672_01825
COV95445; COV95445; ERS007679_02774
COW10404; COW10404; ERS007726_00070
COW15852; COW15852; ERS007720_01865
COW19380; COW19380; ERS007722_01989
COW33823; COW33823; ERS007728_00301
COW35714; COW35714; ERS007731_00165
COW82087; COW82087; ERS007739_00141
COW92887; COW92887; ERS007741_03447
CRH09473; CRH09473; BN1213_00194
CRH15702; CRH15702; BN1303_03284
GeneIDi23493821
PATRICifig|1773.206.peg.3486

Family and domain databases

Gene3Di3.10.129.30, 1 hit
InterProiView protein in InterPro
IPR022598, FcoT_ThioEstase
IPR043064, FcoT_ThioEstase_Rv0098-like_sf
PfamiView protein in Pfam
PF10862, FcoT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A045GLC3_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A045GLC3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: August 12, 2020
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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