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Protein
Submitted name:

Spastic paraplegia 20 isoform 1

Gene

SPG20

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Spastic paraplegia 20 isoform 1Imported
Submitted name:
Spastic paraplegia 20, spartin (Troyer syndrome), isoform CRA_aImported
Gene namesi
Name:SPG20Imported
ORF Names:hCG_32832Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000133104.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000133104 Expressed in 227 organ(s), highest expression level in corpus callosum

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 94MITInterPro annotationAdd BLAST79

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili78 – 98Sequence analysisAdd BLAST21
Coiled coili644 – 664Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2709 Eukaryota
ENOG410ZEPM LUCA
KOiK19366
OMAiVKHKYGA
OrthoDBiEOG091G06VD

Family and domain databases

InterProiView protein in InterPro
IPR007330 MIT
IPR036181 MIT_dom_sf
IPR009686 Senescence/spartin
PfamiView protein in Pfam
PF06911 Senescence, 1 hit
SMARTiView protein in SMART
SM00745 MIT, 1 hit
SUPFAMiSSF116846 SSF116846, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024RDV9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQEPQNGEP AEIKIIREAY KKAFLFVNKG LNTDELGQKE EAKNYYKQGI
60 70 80 90 100
GHLLRGISIS SKESEHTGPG WESARQMQQK MKETLQNVRT RLEILEKGLA
110 120 130 140 150
TSLQNDLQEV PKLYPEFPPK DMCEKLPEPQ SFSSAPQHAE VNGNTSTPSA
160 170 180 190 200
GAVAAPASLS LPSQSCPAEA PPAYTPQAAE GHYTVSYGTD SGEFSSVGEE
210 220 230 240 250
FYRNHSQPPP LETLGLDADE LILIPNGVQI FFVNPAGEVS APSYPGYLRI
260 270 280 290 300
VRFLDNSLDT VLNRPPGFLQ VCDWLYPLVP DRSPVLKCTA GAYMFPDTML
310 320 330 340 350
QAAGCFVGVV LSSELPEDDR ELFEDLLRQM SDLRLQANWN RAEEENEFQI
360 370 380 390 400
PGRTRPSSDQ LKEASGTDVK QLDQGNKDVR HKGKRGKRAK DTSSEEVNLS
410 420 430 440 450
HIVPCEPVPE EKPKELPEWS EKVAHNILSG ASWVSWGLVK GAEITGKAIQ
460 470 480 490 500
KGASKLRERI QPEEKPVEVS PAVTKGLYIA KQATGGAAKV SQFLVDGVCT
510 520 530 540 550
VANCVGKELA PHVKKHGSKL VPESLKKDKD GKSPLDGAMV VAASSVQGFS
560 570 580 590 600
TVWQGLECAA KCIVNNVSAE TVQTVRYKYG YNAGEATHHA VDSAVNVGVT
610 620 630 640 650
AYNINNIGIK AMVKKTATQT GHTLLEDYQI VDNSQRENQE GAANVNVRGE
660
KDEQTKEVKE AKKKDK
Length:666
Mass (Da):72,833
Last modified:July 9, 2014 - v1
Checksum:iCFC8DF65494427CE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei666Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU178563 mRNA Translation: ALQ34021.1
CH471075 Genomic DNA Translation: EAX08558.1
CH471075 Genomic DNA Translation: EAX08559.1
CH471075 Genomic DNA Translation: EAX08560.1
CH471075 Genomic DNA Translation: EAX08562.1
RefSeqiNP_001135766.1, NM_001142294.1
NP_001135767.1, NM_001142295.1
NP_001135768.1, NM_001142296.1
NP_055902.1, NM_015087.4
XP_005266370.1, XM_005266313.4
XP_005266371.1, XM_005266314.3
XP_005266372.1, XM_005266315.3
XP_005266374.1, XM_005266317.3
XP_011533314.1, XM_011535012.2
UniGeneiHs.440414

Genome annotation databases

GeneIDi23111
KEGGihsa:23111

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU178563 mRNA Translation: ALQ34021.1
CH471075 Genomic DNA Translation: EAX08558.1
CH471075 Genomic DNA Translation: EAX08559.1
CH471075 Genomic DNA Translation: EAX08560.1
CH471075 Genomic DNA Translation: EAX08562.1
RefSeqiNP_001135766.1, NM_001142294.1
NP_001135767.1, NM_001142295.1
NP_001135768.1, NM_001142296.1
NP_055902.1, NM_015087.4
XP_005266370.1, XM_005266313.4
XP_005266371.1, XM_005266314.3
XP_005266372.1, XM_005266315.3
XP_005266374.1, XM_005266317.3
XP_011533314.1, XM_011535012.2
UniGeneiHs.440414

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23111
KEGGihsa:23111

Organism-specific databases

CTDi23111
EuPathDBiHostDB:ENSG00000133104.12

Phylogenomic databases

eggNOGiKOG2709 Eukaryota
ENOG410ZEPM LUCA
KOiK19366
OMAiVKHKYGA
OrthoDBiEOG091G06VD

Miscellaneous databases

ChiTaRSiSPG20 human
GenomeRNAii23111

Gene expression databases

BgeeiENSG00000133104 Expressed in 227 organ(s), highest expression level in corpus callosum

Family and domain databases

InterProiView protein in InterPro
IPR007330 MIT
IPR036181 MIT_dom_sf
IPR009686 Senescence/spartin
PfamiView protein in Pfam
PF06911 Senescence, 1 hit
SMARTiView protein in SMART
SM00745 MIT, 1 hit
SUPFAMiSSF116846 SSF116846, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RDV9_HUMAN
AccessioniPrimary (citable) accession number: A0A024RDV9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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