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Protein
Submitted name:

Integrator complex subunit 12, isoform CRA_a

Gene

INTS12

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Integrator complex subunit 12, isoform CRA_aImported
Gene namesi
Name:INTS12Imported
ORF Names:hCG_2030624Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000138785.14

PTM / Processingi

Proteomic databases

PRIDEiA0A024RDK4

Expressioni

Gene expression databases

BgeeiENSG00000138785 Expressed in 222 organ(s), highest expression level in myocardium
ExpressionAtlasiA0A024RDK4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024RDK4
SMRiA0A024RDK4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini159 – 215PHD-typeInterPro annotationAdd BLAST57

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4323 Eukaryota
ENOG410XQ6E LUCA
KOiK13149
OMAiSSKHGHK
OrthoDBiEOG091G0KPP
PhylomeDBiA0A024RDK4

Family and domain databases

CDDicd15501 PHD_Int12, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR039053 Int12
IPR039054 Int12_PHD
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR13415 PTHR13415, 1 hit
PfamiView protein in Pfam
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024RDK4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATVNLELD PIFLKALGFL HSKSKDSAEK LKALLDESLA RGIDSSYRPS
60 70 80 90 100
QKDVEPPKIS STKNISIKQE PKISSSLPSG NNNGKVLTTE KVKKEAEKRP
110 120 130 140 150
ADKMKSDITE GVDIPKKPRL EKPETQSSPI TVQSSKDLPM ADLSSFEETS
160 170 180 190 200
ADDFAMEMGL ACVVCRQMMV ASGNQLVECQ ECHNLYHRDC HKPQVTDKEA
210 220 230 240 250
NDPRLVWYCA RCTRQMKRMA QKTQKPPQKP APAVVSVTPA VKDPLVKKPE
260 270 280 290 300
TKLKQETTFL AFKRTEVKTS TVISGNSSSA SVSSSVTSGL TGWAAFAAKT
310 320 330 340 350
SSAGPSTAKL SSTTQNNTGK PATSSANQKP VGLTGLATSS KGGIGSKIGS
360 370 380 390 400
NNSTTPTVPL KPPPPLTLGK TGLSRSVSCD NVSKVGLPSP SSLVPGSSSQ
410 420 430 440 450
LSGNGNSGTS GPSGSTTSKT TSESSSSPSA SLKGPTSQES QLNAMKRLQM
460
VKKKAAQKKL KK
Length:462
Mass (Da):48,808
Last modified:July 9, 2014 - v1
Checksum:i7AEF952044A3E951
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471057 Genomic DNA Translation: EAX06190.1
RefSeqiNP_001135943.1, NM_001142471.1
NP_065128.2, NM_020395.3
XP_005263205.1, XM_005263148.4
XP_011530445.1, XM_011532143.2
XP_011530447.1, XM_011532145.2
UniGeneiHs.480454

Genome annotation databases

GeneIDi57117
KEGGihsa:57117

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471057 Genomic DNA Translation: EAX06190.1
RefSeqiNP_001135943.1, NM_001142471.1
NP_065128.2, NM_020395.3
XP_005263205.1, XM_005263148.4
XP_011530445.1, XM_011532143.2
XP_011530447.1, XM_011532145.2
UniGeneiHs.480454

3D structure databases

ProteinModelPortaliA0A024RDK4
SMRiA0A024RDK4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024RDK4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi57117
KEGGihsa:57117

Organism-specific databases

CTDi57117
EuPathDBiHostDB:ENSG00000138785.14

Phylogenomic databases

eggNOGiKOG4323 Eukaryota
ENOG410XQ6E LUCA
KOiK13149
OMAiSSKHGHK
OrthoDBiEOG091G0KPP
PhylomeDBiA0A024RDK4

Miscellaneous databases

GenomeRNAii57117

Gene expression databases

BgeeiENSG00000138785 Expressed in 222 organ(s), highest expression level in myocardium
ExpressionAtlasiA0A024RDK4 baseline and differential

Family and domain databases

CDDicd15501 PHD_Int12, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR039053 Int12
IPR039054 Int12_PHD
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR13415 PTHR13415, 1 hit
PfamiView protein in Pfam
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RDK4_HUMAN
AccessioniPrimary (citable) accession number: A0A024RDK4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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