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Protein
Submitted name:

Kinesin light chain 4, isoform CRA_a

Gene

KLC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin light chain 4, isoform CRA_aImported
Gene namesi
Name:KLC4Imported
ORF Names:hCG_17653Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000137171.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000137171 Expressed in 190 organ(s), highest expression level in right lobe of liver

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini211 – 412TPR_REGIONInterPro annotationAdd BLAST202
Repeati211 – 244TPRPROSITE-ProRule annotationAdd BLAST34
Repeati253 – 286TPRPROSITE-ProRule annotationAdd BLAST34
Repeati295 – 328TPRPROSITE-ProRule annotationAdd BLAST34
Repeati337 – 370TPRPROSITE-ProRule annotationAdd BLAST34
Repeati379 – 412TPRPROSITE-ProRule annotationAdd BLAST34
Repeati464 – 497TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili95 – 150Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1840 Eukaryota
COG0457 LUCA
KOiK10407

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR002151 Kinesin_light
IPR015792 Kinesin_light_repeat
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PRINTSiPR00381 KINESINLIGHT
SMARTiView protein in SMART
SM00028 TPR, 5 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS01160 KINESIN_LIGHT, 1 hit
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024RCZ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGLVLGQRD EPAGHRLSQE EILGSTRLVS QGLEALRSEH QAVLQSLSQT
60 70 80 90 100
IECLQQGGHE EGLVHEKARQ LRRSMENIEL GLSEAQVMLA LASHLSTVES
110 120 130 140 150
EKQKLRAQVR RLCQENQWLR DELAGTQQRL QRSEQAVAQL EEEKKHLEFL
160 170 180 190 200
GQLRQYDEDG HTSEEKEGDA TKDSLDDLFP NEEEEDPSNG LSRGQGATAA
210 220 230 240 250
QQGGYEIPAR LRTLHNLVIQ YAAQGRYEVA VPLCKQALED LERTSGRGHP
260 270 280 290 300
DVATMLNILA LVYRDQNKYK EAAHLLNDAL SIRESTLGPD HPAVAATLNN
310 320 330 340 350
LAVLYGKRGK YKEAEPLCQR ALEIREKVLG TNHPDVAKQL NNLALLCQNQ
360 370 380 390 400
GKYEAVERYY QRALAIYEGQ LGPDNPNVAR TKNNLASCYL KQGKYAEAET
410 420 430 440 450
LYKEILTRAH VQEFGSVDDD HKPIWMHAEE REEMSKSRHH EGGTPYAEYG
460 470 480 490 500
GWYKACKVSS PTVNTTLRNL GALYRRQGKL EAAETLEECA LRSRRQGTDP
510 520 530 540 550
ISQTKVAELL GESDGRRTSQ EGPGDSVKFE GGEDASVAVE WSGDGSGTLQ
560 570 580 590 600
RSGSLGKIRD VLRRSSELLV RKLQGTEPRP SSSNMKRAAS LNYLNQPSAA
610
PLQVSRGLSA STMDLSSSS
Length:619
Mass (Da):68,640
Last modified:July 9, 2014 - v1
Checksum:i32DFC2A9A91B5574
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471081 Genomic DNA Translation: EAX04146.1
CH471081 Genomic DNA Translation: EAX04148.1
RefSeqiNP_001275963.1, NM_001289034.1
NP_958929.1, NM_201521.2
NP_958930.1, NM_201522.2
UniGeneiHs.655123

Genome annotation databases

GeneIDi89953
KEGGihsa:89953

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471081 Genomic DNA Translation: EAX04146.1
CH471081 Genomic DNA Translation: EAX04148.1
RefSeqiNP_001275963.1, NM_001289034.1
NP_958929.1, NM_201521.2
NP_958930.1, NM_201522.2
UniGeneiHs.655123

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi89953
KEGGihsa:89953

Organism-specific databases

CTDi89953
EuPathDBiHostDB:ENSG00000137171.14

Phylogenomic databases

eggNOGiKOG1840 Eukaryota
COG0457 LUCA
KOiK10407

Miscellaneous databases

ChiTaRSiKLC4 human
GenomeRNAii89953

Gene expression databases

BgeeiENSG00000137171 Expressed in 190 organ(s), highest expression level in right lobe of liver

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR002151 Kinesin_light
IPR015792 Kinesin_light_repeat
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PRINTSiPR00381 KINESINLIGHT
SMARTiView protein in SMART
SM00028 TPR, 5 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS01160 KINESIN_LIGHT, 1 hit
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RCZ8_HUMAN
AccessioniPrimary (citable) accession number: A0A024RCZ8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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