UniProtKB - A0A024RC04 (A0A024RC04_HUMAN)
Protein
Submitted name:
Zinc finger protein, X-linked, isoform CRA_a
Gene
ZFX
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
- metal ion binding Source: InterPro
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein, X-linked, isoform CRA_aImported |
Gene namesi | Name:ZFXImported ORF Names:hCG_18656Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000005889.15 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleolus Source: HPA
- nucleoplasm Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000005889, Expressed in kidney and 225 other tissues |
ExpressionAtlasi | A0A024RC04, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 425 – 455 | C2H2-typeInterPro annotationAdd BLAST | 31 | |
Domaini | 456 – 478 | C2H2-typeInterPro annotationAdd BLAST | 23 | |
Domaini | 488 – 515 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 519 – 547 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 548 – 575 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 576 – 604 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 605 – 632 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 633 – 661 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 662 – 689 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 690 – 718 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 719 – 746 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 747 – 775 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 776 – 803 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationFamily and domain databases
InterProi | View protein in InterPro IPR006794, Transcrp_activ_Zfx/Zfy-dom IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 7 hits PF04704, Zfx_Zfy_act, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
i Sequence
Sequence statusi: Complete.
A0A024RC04-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDEDGLELQQ EPNSFFDATG ADGTHMDGDQ IVVEVQETVF VSDVVDSDIT
60 70 80 90 100
VHNFVPDDPD SVVIQDVIED VVIEDVQCPD IMEEADVSET VIIPEQVLDS
110 120 130 140 150
DVTEEVSLAH CTVPDDVLAS DITSASMSMP EHVLTGDSIH VSDVGHVGHV
160 170 180 190 200
GHVEHVVHDS VVEAEIVTDP LTTDVVSEEV LVADCASEAV IDANGIPVDQ
210 220 230 240 250
QDDDKGNCED YLMISLDDAG KIEHDGSSGM TMDTESEIDP CKVDGTCPEV
260 270 280 290 300
IKVYIFKADP GEDDLGGTVD IVESEPENDH GVELLDQNSS IRVPREKMVY
310 320 330 340 350
MTVNDSQPED EDLNVAEIAD EVYMEVIVGE EDAAAAAAAA AVHEQQMDDN
360 370 380 390 400
EIKTFMPIAW AAAYGNNSDG IENRNGTASA LLHIDESAGL GRLAKQKPKK
410 420 430 440 450
RRRPDSRQYQ TAIIIGPDGH PLTVYPCMIC GKKFKSRGFL KRHMKNHPEH
460 470 480 490 500
LAKKKYRCTD CDYTTNKKIS LHNHLESHKL TSKAEKAIEC DECGKHFSHA
510 520 530 540 550
GALFTHKMVH KEKGANKMHK CKFCEYETAE QGLLNRHLLA VHSKNFPHIC
560 570 580 590 600
VECGKGFRHP SELKKHMRIH TGEKPYQCQY CEYRSADSSN LKTHVKTKHS
610 620 630 640 650
KEMPFKCDIC LLTFSDTKEV QQHALIHQES KTHQCLHCDH KSSNSSDLKR
660 670 680 690 700
HIISVHTKDY PHKCDMCDKG FHRPSELKKH VAAHKGKKMH QCRHCDFKIA
710 720 730 740 750
DPFVLSRHIL SVHTKDLPFR CKRCRKGFRQ QSELKKHMKT HSGRKVYQCE
760 770 780 790 800
YCEYSTTDAS GFKRHVISIH TKDYPHRCEY CKKGFRRPSE KNQHIMRHHK
EVGLP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471074 Genomic DNA Translation: EAW99013.1 CH471074 Genomic DNA Translation: EAW99014.1 CH471074 Genomic DNA Translation: EAW99015.1 |
RefSeqi | NP_001171555.1, NM_001178084.1 NP_001171556.1, NM_001178085.1 NP_003401.2, NM_003410.3 XP_005274648.1, XM_005274591.4 XP_005274649.1, XM_005274592.3 XP_011543881.1, XM_011545579.1 XP_011543883.1, XM_011545581.2 XP_016885283.1, XM_017029794.1 XP_016885284.1, XM_017029795.1 |
Genome annotation databases
GeneIDi | 7543 |
KEGGi | hsa:7543 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471074 Genomic DNA Translation: EAW99013.1 CH471074 Genomic DNA Translation: EAW99014.1 CH471074 Genomic DNA Translation: EAW99015.1 |
RefSeqi | NP_001171555.1, NM_001178084.1 NP_001171556.1, NM_001178085.1 NP_003401.2, NM_003410.3 XP_005274648.1, XM_005274591.4 XP_005274649.1, XM_005274592.3 XP_011543881.1, XM_011545579.1 XP_011543883.1, XM_011545581.2 XP_016885283.1, XM_017029794.1 XP_016885284.1, XM_017029795.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 577, 169 antibodies |
Genome annotation databases
GeneIDi | 7543 |
KEGGi | hsa:7543 |
Organism-specific databases
CTDi | 7543 |
VEuPathDBi | HostDB:ENSG00000005889.15 |
Miscellaneous databases
BioGRID-ORCSi | 7543, 51 hits in 523 CRISPR screens |
ChiTaRSi | ZFX, human |
GenomeRNAii | 7543 |
Gene expression databases
Bgeei | ENSG00000005889, Expressed in kidney and 225 other tissues |
ExpressionAtlasi | A0A024RC04, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR006794, Transcrp_activ_Zfx/Zfy-dom IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 7 hits PF04704, Zfx_Zfy_act, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024RC04_HUMAN | |
Accessioni | A0A024RC04Primary (citable) accession number: A0A024RC04 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | February 10, 2021 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |