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Protein
Submitted name:

Acetoacetyl-CoA synthetase, isoform CRA_b

Gene

AACS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Acetoacetyl-CoA synthetase, isoform CRA_bImported
Gene namesi
Name:AACSImported
ORF Names:hCG_32866Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000081760.16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024RBV2

Expressioni

Gene expression databases

BgeeiENSG00000081760
ExpressionAtlasiA0A024RBV2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024RBV2
SMRiA0A024RBV2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 104ACAS_NInterPro annotationAdd BLAST58
Domaini109 – 543AMP-bindingInterPro annotationAdd BLAST435

Phylogenomic databases

eggNOGiKOG1175 Eukaryota
COG0365 LUCA
KOiK01907
OMAiYEYVYRC
OrthoDBiEOG091G05B0
PhylomeDBiA0A024RBV2

Family and domain databases

InterProiView protein in InterPro
IPR005914 Acac_CoA_synth
IPR032387 ACAS_N
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
PfamiView protein in Pfam
PF16177 ACAS_N, 1 hit
PF00501 AMP-binding, 1 hit
TIGRFAMsiTIGR01217 ac_ac_CoA_syn, 1 hit
PROSITEiView protein in PROSITE
PS00455 AMP_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024RBV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKEERPGRE EILECQVMWE PDSKKNTQMD RFRAAVGAAC GLALESYDDL
60 70 80 90 100
YHWSVESYSD FWAEFWKFSG IVFSRVYDEV VDTSKGIADV PEWFKGSRLN
110 120 130 140 150
YAENLLRHKE NDRVALYIAR EGKEEIVKVT FEELRQEVAL FAAAMRKMGV
160 170 180 190 200
KKGDRVVGYL PNSEHAVEAM LAAASIGAIW SSTSPDFGVN GVLDRFSQIQ
210 220 230 240 250
PKLIFSVEAV VYNGKEHNHM EKLQQVVKGL PDLKKVVVIP YVSSRENIDL
260 270 280 290 300
SKIPNSVFLD DFLATGTSEQ APQLEFEQLP FSHPLFIMFS SGTTGAPKCM
310 320 330 340 350
VHSAGGTLIQ HLKEHLLHGN MTSSDILLCY TTVGWMMWNW MVSLLATGAA
360 370 380 390 400
MVLYDGSPLV PTPNVLWDLV DRIGITVLVT GAKWLSVLEE KAMKPVETHS
410 420 430 440 450
LQMLHTILST GSPLKAQSYE YVYRCIKSSI LLGSISGGTD IISCFMGHNF
460 470 480 490 500
SLPVYKGEIQ ARNLGMAVEA WNEEGKAVWG ESGELVCTKP IPCQPTHFWN
510 520 530 540 550
DENGNKYRKA YFSKFPGIWA HGDYCRINPK TGGIVMLGRS DGTLNPNGVR
560 570 580 590 600
FGSSEIYNIV ESFEEVEDSL CVPQYNKYRE ERVILFLKMA SGHAFQPDLV
610 620 630 640 650
KRIRDAIRMG LSARHVPSLI LETKGIPYTL NGKKVEVAVK QIIAGKAVEQ
660 670
GGAFSNPETL DLYRDIPELQ GF
Length:672
Mass (Da):75,144
Last modified:July 9, 2014 - v1
Checksum:i36006739EE4857D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471054 Genomic DNA Translation: EAW98475.1
RefSeqiNP_076417.2, NM_023928.4
UniGeneiHs.656073

Genome annotation databases

GeneIDi65985
KEGGihsa:65985

Similar proteinsi

Entry informationi

Entry nameiA0A024RBV2_HUMAN
AccessioniPrimary (citable) accession number: A0A024RBV2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: February 28, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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