UniProtKB - A0A024RBH2 (A0A024RBH2_HUMAN)
Protein
Submitted name:
Cytoskeleton-associated protein 4, isoform CRA_c
Gene
CKAP4
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Cytoskeleton-associated protein 4, isoform CRA_cImported |
Gene namesi | Name:CKAP4Imported ORF Names:hCG_16102Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000136026.13 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Endoplasmic reticulum
- endoplasmic reticulum Source: Ensembl
Nucleus
- nuclear speck Source: HPA
Other locations
- cytoplasmic ribonucleoprotein granule Source: HPA
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 110 – 131 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000136026, Expressed in tibia and 254 other tissues |
ExpressionAtlasi | A0A024RBH2, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 83 | DisorderedSequence analysisAdd BLAST | 83 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 148 – 168 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 190 – 210 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 259 – 296 | Sequence analysisAdd BLAST | 38 | |
Coiled coili | 356 – 383 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 434 – 454 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 536 – 556 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 567 – 601 | Sequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 36 – 54 | Pro-richSequence analysisAdd BLAST | 19 |
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
HOGENOMi | CLU_032481_0_0_1 |
OMAi | SEGYKQD |
OrthoDBi | 1255457at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR028428, Ckap4 |
PANTHERi | PTHR45161, PTHR45161, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A024RBH2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPSAKQRGSK GGHGAASPSE KGAHPSGGAD DVAKKPPPAP QQPPPPPAPH
60 70 80 90 100
PQQHPQQHPQ NQAHGKGGHR GGGGGGGKSS SSSSASAAAA AAAASSSASC
110 120 130 140 150
SRRLGRALNF LFYLALVAAA AFSGWCVHHV LEEVQQVRRS HQDFSRQREE
160 170 180 190 200
LGQGLQGVEQ KVQSLQATFG TFESILRSSQ HKQDLTEKAV KQGESEVSRI
210 220 230 240 250
SEVLQKLQNE ILKDLSDGIH VVKDARERDF TSLENTVEER LTELTKSIND
260 270 280 290 300
NIAIFTEVQK RSQKEINDMK AKVASLEESE GNKQDLKALK EAVKEIQTSA
310 320 330 340 350
KSREWDMEAL RSTLQTMESD IYTEVRELVS LKQEQQAFKE AADTERLALQ
360 370 380 390 400
ALTEKLLRSE ESVSRLPEEI RRLEEELRQL KSDSHGPKED GGFRHSEAFE
410 420 430 440 450
ALQQKSQGLD SRLQHVEDGV LSMQVASARQ TESLESLLSK SQEHEQRLAA
460 470 480 490 500
LQGRLEGLGS SEADQDGLAS TVRSLGETQL VLYGDVEELK RSVGELPSTV
510 520 530 540 550
ESLQKVQEQV HTLLSQDQAQ AARLPPQDFL DRLSSLDNLK ASVSQVEADL
560 570 580 590 600
KMLRTAVDSL VAYSVKIETN ENNLESAKGL LDDLRNDLDR LFVKVEKIHE
KV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471054 Genomic DNA Translation: EAW97772.1 CH471054 Genomic DNA Translation: EAW97773.1 |
RefSeqi | NP_006816.2, NM_006825.3 |
Genome annotation databases
GeneIDi | 10970 |
KEGGi | hsa:10970 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471054 Genomic DNA Translation: EAW97772.1 CH471054 Genomic DNA Translation: EAW97773.1 |
RefSeqi | NP_006816.2, NM_006825.3 |
3D structure databases
SMRi | A0A024RBH2 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | A0A024RBH2, 1 interactor |
Protocols and materials databases
Antibodypediai | 613, 274 antibodies |
Genome annotation databases
GeneIDi | 10970 |
KEGGi | hsa:10970 |
Organism-specific databases
CTDi | 10970 |
EuPathDBi | HostDB:ENSG00000136026.13 |
Phylogenomic databases
HOGENOMi | CLU_032481_0_0_1 |
OMAi | SEGYKQD |
OrthoDBi | 1255457at2759 |
Miscellaneous databases
BioGRID-ORCSi | 10970, 4 hits in 846 CRISPR screens |
ChiTaRSi | CKAP4, human |
GenomeRNAii | 10970 |
Gene expression databases
Bgeei | ENSG00000136026, Expressed in tibia and 254 other tissues |
ExpressionAtlasi | A0A024RBH2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR028428, Ckap4 |
PANTHERi | PTHR45161, PTHR45161, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024RBH2_HUMAN | |
Accessioni | A0A024RBH2Primary (citable) accession number: A0A024RBH2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | December 2, 2020 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |