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Protein
Submitted name:

Solute carrier family 16 (Monocarboxylic acid transporters), member 7, isoform CRA_a

Gene

SLC16A7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 16 (Monocarboxylic acid transporters), member 7, isoform CRA_aImported
Gene namesi
Name:SLC16A7Imported
ORF Names:hCG_39108Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000118596.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei18 – 36HelicalSequence analysisAdd BLAST19
Transmembranei58 – 80HelicalSequence analysisAdd BLAST23
Transmembranei87 – 106HelicalSequence analysisAdd BLAST20
Transmembranei112 – 134HelicalSequence analysisAdd BLAST23
Transmembranei146 – 164HelicalSequence analysisAdd BLAST19
Transmembranei176 – 198HelicalSequence analysisAdd BLAST23
Transmembranei247 – 268HelicalSequence analysisAdd BLAST22
Transmembranei280 – 303HelicalSequence analysisAdd BLAST24
Transmembranei315 – 335HelicalSequence analysisAdd BLAST21
Transmembranei341 – 359HelicalSequence analysisAdd BLAST19
Transmembranei405 – 427HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSG00000118596 Expressed in 236 organ(s), highest expression level in heart left ventricle

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 436MFSInterPro annotationAdd BLAST418

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IMVS Eukaryota
ENOG4111F0K LUCA
KOiK08184
OMAiGQYKYMY
OrthoDBiEOG091G05SW

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR004743 MCT
IPR027178 MCT2
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PANTHERiPTHR11360:SF25 PTHR11360:SF25, 1 hit
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00892 2A0113, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024RBB2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPMPSAPPV HPPPDGGWGW IVVGAAFISI GFSYAFPKAV TVFFKEIQQI
60 70 80 90 100
FHTTYSEIAW ISSIMLAVMY AGGPVSSVLV NKYGSRPVVI AGGLLCCLGM
110 120 130 140 150
VLASFSSSVV QLYLTMGFIT GLGLAFNLQP ALTIIGKYFY RKRPMANGLA
160 170 180 190 200
MAGSPVFLSS LAPFNQYLFN TFGWKGSFLI LGSLLLNACV AGSLMRPLGP
210 220 230 240 250
NQTTSKSKNK TGKTEDDSSP KKIKTKKSTW EKVNKYLDFS LFKHRGFLIY
260 270 280 290 300
LSGNVIMFLG FFAPIIFLAP YAKDQGIDEY SAAFLLSVMA FVDMFARPSV
310 320 330 340 350
GLIANSKYIR PRIQYFFSFA IMFNGVCHLL CPLAQDYTSL VLYAVFFGLG
360 370 380 390 400
FGSVSSVLFE TLMDLVGAPR FSSAVGLVTI VECGPVLLGP PLAGKLVDLT
410 420 430 440 450
GEYKYMYMSC GAIVVAASVW LLIGNAINYR LLAKERKEEN ARQKTRESEP
460 470
LSKSKHSEDV NVKVSNAQSV TSERETNI
Length:478
Mass (Da):52,200
Last modified:July 9, 2014 - v1
Checksum:iE508D650E8D7DE98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471054 Genomic DNA Translation: EAW97097.1
CH471054 Genomic DNA Translation: EAW97098.1
CH471054 Genomic DNA Translation: EAW97099.1
RefSeqiNP_001257551.1, NM_001270622.1
NP_001257552.1, NM_001270623.1
NP_004722.2, NM_004731.4
XP_005269288.1, XM_005269231.4
UniGeneiHs.439643
Hs.88156

Genome annotation databases

GeneIDi9194
KEGGihsa:9194

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471054 Genomic DNA Translation: EAW97097.1
CH471054 Genomic DNA Translation: EAW97098.1
CH471054 Genomic DNA Translation: EAW97099.1
RefSeqiNP_001257551.1, NM_001270622.1
NP_001257552.1, NM_001270623.1
NP_004722.2, NM_004731.4
XP_005269288.1, XM_005269231.4
UniGeneiHs.439643
Hs.88156

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9194
KEGGihsa:9194

Organism-specific databases

CTDi9194
EuPathDBiHostDB:ENSG00000118596.11

Phylogenomic databases

eggNOGiENOG410IMVS Eukaryota
ENOG4111F0K LUCA
KOiK08184
OMAiGQYKYMY
OrthoDBiEOG091G05SW

Miscellaneous databases

ChiTaRSiSLC16A7 human
GenomeRNAii9194

Gene expression databases

BgeeiENSG00000118596 Expressed in 236 organ(s), highest expression level in heart left ventricle

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR004743 MCT
IPR027178 MCT2
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PANTHERiPTHR11360:SF25 PTHR11360:SF25, 1 hit
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00892 2A0113, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RBB2_HUMAN
AccessioniPrimary (citable) accession number: A0A024RBB2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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