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Protein
Submitted name:

Pleckstrin homology domain containing, family A member 5, isoform CRA_a

Gene

PLEKHA5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Pleckstrin homology domain containing, family A member 5, isoform CRA_aImported
Gene namesi
Name:PLEKHA5Imported
ORF Names:hCG_1685936Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000052126.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000052126 Expressed in 227 organ(s), highest expression level in female reproductive system

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 43WWInterPro annotationAdd BLAST34
Domaini56 – 89WWInterPro annotationAdd BLAST34
Domaini169 – 268PHInterPro annotationAdd BLAST100

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili306 – 326Sequence analysisAdd BLAST21
Coiled coili707 – 727Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410INUD Eukaryota
ENOG4111YSB LUCA

Family and domain databases

CDDicd00201 WW, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR001202 WW_dom
IPR036020 WW_dom_sf
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00397 WW, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00456 WW, 2 hits
SUPFAMiSSF51045 SSF51045, 2 hits
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 2 hits

Sequencei

Sequence statusi: Complete.

A0A024RAY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAADLNLEWI SLPRSWTYGI TRGGRVFFIN EEAKSTTWLH PVTGEAVVTG
60 70 80 90 100
HRRQSTDLPT GWEEAYTFEG ARYYINHNER KVTCKHPVTG QPSQDNCIFV
110 120 130 140 150
VNEQTVATMT SEEKKERPIS MINEASNYNV TSDYAVHPMS PVGRTSRASK
160 170 180 190 200
KVHNFGKRSN SIKRNPNAPV VRRGWLYKQD STGMKLWKKR WFVLSDLCLF
210 220 230 240 250
YYRDEKEEGI LGSILLPSFQ IALLTSEDHI NRKYAFKAAH PNMRTYYFCT
260 270 280 290 300
DTGKEMELWM KAMLDAALVQ TEPVKRVDKI TSENAPTKET NNIPNHRVLI
310 320 330 340 350
KPEIQNNQKN KEMSKIEEKK ALEAEKYGFQ KDGQDRPLTK INSVKLNSLP
360 370 380 390 400
SEYESGSACP AQTVHYRPIN LSSSENKIVN VSLADLRGGN RPNTGPLYTE
410 420 430 440 450
ADRVIQRTNS MQQLEQWIKI QKGRGHEEET RGVISYQTLP RNMPSHRAQI
460 470 480 490 500
MARYPEGYRT LPRNSKTRPE SICSVTPSTH DKTLGPGAEE KRRSMRDDTM
510 520 530 540 550
WQLYEWQQRQ FYNKQSTLPR HSTLSSPKTM VNISDQTMHS IPTSPSHGSI
560 570 580 590 600
AAYQGYSPQR TYRSEVSSPI QRGDVTIDRR HRAHHPKHVY VPDRRSVPAG
610 620 630 640 650
LTLQSVSPQS LQGKTPEELT LLLIKLRRQQ AELSSIREHT LAQLMQLKLE
660 670 680 690 700
AHSPKNEILS HHLQRNTIYL DHQLSQDEGR GTLYKYRPEE VDIDAKLSRL
710 720 730 740 750
CEQDKVVHAL EEKLQQLHKE KYTLEQALLS ASQEIEMHAD NPAAIQTVVL
760 770 780 790 800
QRDDLQNGLL STCRELSRAT AELERAWREY DKLEYDVTVT RNQMQEQLDH
810 820 830 840 850
LGEVQTESAG IQRAQIQKEL WRIQDVMEGL SKHKQQRGTT EIGMIGSKPF
860 870 880 890 900
STVKYKNEGP DYRLYKSEPE LTTVAEVDES NGEEKSEPVS EIETSVVKGS
910 920 930 940 950
HFPVGVVPPR AKSPTPESST IASYVTLRKT KKMMDLRTER PRSAVEQLCL
960 970 980 990 1000
AESTRPRMTV EEQMERIRRH QQACLREKKK GLNVIGASDQ SPLQSPSNLR
1010 1020 1030 1040 1050
DNPFRTTQTR RRDDKELDTA IRENDVKPDH ETPATEIVQL KETEPQNVDF
1060 1070 1080 1090 1100
SKELKKTENI SYEMLFEPEP NGVNSVEMMD KERNKDKMPE DVTFSPQDET
1110 1120 1130 1140 1150
QTANHKPEEH PEENTKNSVD EQEETVISYE STPEVSRGNQ TMAVKSLSPS
1160 1170
PESSASPVPS TQPQLTEGSH FMCV
Length:1,174
Mass (Da):134,323
Last modified:July 9, 2014 - v1
Checksum:iB82D29C6F281D311
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471094 Genomic DNA Translation: EAW96392.1
CH471094 Genomic DNA Translation: EAW96395.1
RefSeqiNP_001137293.2, NM_001143821.2
XP_011519019.1, XM_011520717.1
UniGeneiHs.188614

Genome annotation databases

GeneIDi54477

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471094 Genomic DNA Translation: EAW96392.1
CH471094 Genomic DNA Translation: EAW96395.1
RefSeqiNP_001137293.2, NM_001143821.2
XP_011519019.1, XM_011520717.1
UniGeneiHs.188614

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi54477

Organism-specific databases

CTDi54477
EuPathDBiHostDB:ENSG00000052126.14

Phylogenomic databases

eggNOGiENOG410INUD Eukaryota
ENOG4111YSB LUCA

Miscellaneous databases

ChiTaRSiPLEKHA5 human
GenomeRNAii54477

Gene expression databases

BgeeiENSG00000052126 Expressed in 227 organ(s), highest expression level in female reproductive system

Family and domain databases

CDDicd00201 WW, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR001202 WW_dom
IPR036020 WW_dom_sf
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00397 WW, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00456 WW, 2 hits
SUPFAMiSSF51045 SSF51045, 2 hits
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RAY7_HUMAN
AccessioniPrimary (citable) accession number: A0A024RAY7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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