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Protein
Submitted name:

Regulator of chromosome condensation 2, isoform CRA_a

Gene

RCC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Regulator of chromosome condensation 2, isoform CRA_aImported
Gene namesi
Name:RCC2Imported
ORF Names:hCG_25129Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000179051.13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000179051 Expressed in 197 organ(s), highest expression level in female gonad

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati169 – 220RCC1PROSITE-ProRule annotationAdd BLAST52
Repeati221 – 272RCC1PROSITE-ProRule annotationAdd BLAST52
Repeati273 – 348RCC1PROSITE-ProRule annotationAdd BLAST76
Repeati349 – 402RCC1PROSITE-ProRule annotationAdd BLAST54
Repeati448 – 502RCC1PROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG1427 Eukaryota
COG5184 LUCA
OMAiVDCKGNL
OrthoDBiEOG091G07AD

Family and domain databases

Gene3Di2.130.10.30, 2 hits
InterProiView protein in InterPro
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
PfamiView protein in Pfam
PF00415 RCC1, 4 hits
PRINTSiPR00633 RCCNDNSATION
SUPFAMiSSF50985 SSF50985, 1 hit
PROSITEiView protein in PROSITE
PS00626 RCC1_2, 2 hits
PS50012 RCC1_3, 5 hits

Sequencei

Sequence statusi: Complete.

A0A024RAC5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRKKAAAAA WEEPSSGNGT ARAGPRKRGG PAGRKRERPE RCSSSSGGGS
60 70 80 90 100
SGDEDGLELD GAPGGGKRAA RPATAGKAGG AAVVITEPEH TKERVKLEGS
110 120 130 140 150
KCKGQLLIFG ATNWDLIGRK EVPKQQAAYR NLGQNLWGPH RYGCLAGVRV
160 170 180 190 200
RTVVSGSCAA HSLLITTEGK LWSWGRNEKG QLGHGDTKRV EAPRLIEGLS
210 220 230 240 250
HEVIVSAACG RNHTLALTET GSVFAFGENK MGQLGLGNQT DAVPSPAQIM
260 270 280 290 300
YNGQPITKMA CGAEFSMIMD CKGNLYSFGC PEYGQLGHNS DGKFIARAQR
310 320 330 340 350
IEYDCELVPR RVAIFIEKTK DGQILPVPNV VVRDVACGAN HTLVLDSQKR
360 370 380 390 400
VFSWGFGGYG RLGHAEQKDE MVPRLVKLFD FPGRGASQIY AGYTCSFAVS
410 420 430 440 450
EVGGLFFWGA TNTSRESTMY PKAVQDLCGW RIRSLACGKS SIIVAADEST
460 470 480 490 500
ISWGPSPTFG ELGYGDHKPK SSTAAQEVKT LDGIFSEQVA MGYSHSLVIA
510 520
RDESETEKEK IKKLPEYNPR TL
Length:522
Mass (Da):56,085
Last modified:July 9, 2014 - v1
Checksum:i7065F70AEA98EDC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471134 Genomic DNA Translation: EAW94838.1
CH471134 Genomic DNA Translation: EAW94839.1
RefSeqiNP_001129676.1, NM_001136204.2
NP_061185.1, NM_018715.3
UniGeneiHs.380857

Genome annotation databases

GeneIDi55920
KEGGihsa:55920

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471134 Genomic DNA Translation: EAW94838.1
CH471134 Genomic DNA Translation: EAW94839.1
RefSeqiNP_001129676.1, NM_001136204.2
NP_061185.1, NM_018715.3
UniGeneiHs.380857

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi55920
KEGGihsa:55920

Organism-specific databases

CTDi55920
EuPathDBiHostDB:ENSG00000179051.13

Phylogenomic databases

eggNOGiKOG1427 Eukaryota
COG5184 LUCA
OMAiVDCKGNL
OrthoDBiEOG091G07AD

Miscellaneous databases

ChiTaRSiRCC2 human
GenomeRNAii55920

Gene expression databases

BgeeiENSG00000179051 Expressed in 197 organ(s), highest expression level in female gonad

Family and domain databases

Gene3Di2.130.10.30, 2 hits
InterProiView protein in InterPro
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
PfamiView protein in Pfam
PF00415 RCC1, 4 hits
PRINTSiPR00633 RCCNDNSATION
SUPFAMiSSF50985 SSF50985, 1 hit
PROSITEiView protein in PROSITE
PS00626 RCC1_2, 2 hits
PS50012 RCC1_3, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RAC5_HUMAN
AccessioniPrimary (citable) accession number: A0A024RAC5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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