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Protein
Submitted name:

PQ loop repeat containing 2, isoform CRA_c

Gene

PQLC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
PQ loop repeat containing 2, isoform CRA_cImported
Gene namesi
Name:PQLC2Imported
ORF Names:hCG_41084Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000040487.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 58HelicalSequence analysisAdd BLAST22
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei102 – 119HelicalSequence analysisAdd BLAST18
Transmembranei131 – 157HelicalSequence analysisAdd BLAST27
Transmembranei177 – 197HelicalSequence analysisAdd BLAST21
Transmembranei217 – 236HelicalSequence analysisAdd BLAST20
Transmembranei256 – 276HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSG00000040487 Expressed in 120 organ(s), highest expression level in right hemisphere of cerebellum

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2913 Eukaryota
ENOG4111FM2 LUCA
OMAiACWIIVF
OrthoDBiEOG091G0C7E

Family and domain databases

InterProiView protein in InterPro
IPR006603 PQ-loop_rpt
PfamiView protein in Pfam
PF04193 PQ-loop, 2 hits
SMARTiView protein in SMART
SM00679 CTNS, 2 hits

Sequencei

Sequence statusi: Complete.

A0A024RA97-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVWKKLGSRN FSSCPSGSIQ WIWDVLGECA QDGWDEASVG LGLISILCFA
60 70 80 90 100
ASTFPQFIKA YKTGNMDQAL SLWFLLGWIG GDSCNLIGSF LADQLPLQTY
110 120 130 140 150
TAVYYVLADL VMLTLYFYYK FRTRPSLLSA PINSVLLFLM GMACATPLLS
160 170 180 190 200
AAGPVAAPRE AFRGRALLSV ESGSKPFTRQ EVIGFVIGSI SSVLYLLSRL
210 220 230 240 250
PQIRTNFLRK STQGISYSLF ALVMLGNTLY GLSVLLKNPE EGQSEGSYLL
260 270 280 290
HHLPWLVGSL GVLLLDTIIS IQFLVYRRST AASELEPLLP S
Length:291
Mass (Da):31,947
Last modified:July 9, 2014 - v1
Checksum:iB544D3BFA5458920
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471134 Genomic DNA Translation: EAW94884.1
CH471134 Genomic DNA Translation: EAW94885.1
CH471134 Genomic DNA Translation: EAW94887.1
RefSeqiNP_001035214.1, NM_001040125.1
NP_060235.2, NM_017765.2
XP_005245973.1, XM_005245916.2
UniGeneiHs.647620

Genome annotation databases

GeneIDi54896
KEGGihsa:54896

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471134 Genomic DNA Translation: EAW94884.1
CH471134 Genomic DNA Translation: EAW94885.1
CH471134 Genomic DNA Translation: EAW94887.1
RefSeqiNP_001035214.1, NM_001040125.1
NP_060235.2, NM_017765.2
XP_005245973.1, XM_005245916.2
UniGeneiHs.647620

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi54896
KEGGihsa:54896

Organism-specific databases

CTDi54896
EuPathDBiHostDB:ENSG00000040487.12

Phylogenomic databases

eggNOGiKOG2913 Eukaryota
ENOG4111FM2 LUCA
OMAiACWIIVF
OrthoDBiEOG091G0C7E

Miscellaneous databases

ChiTaRSiPQLC2 human
GenomeRNAii54896

Gene expression databases

BgeeiENSG00000040487 Expressed in 120 organ(s), highest expression level in right hemisphere of cerebellum

Family and domain databases

InterProiView protein in InterPro
IPR006603 PQ-loop_rpt
PfamiView protein in Pfam
PF04193 PQ-loop, 2 hits
SMARTiView protein in SMART
SM00679 CTNS, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RA97_HUMAN
AccessioniPrimary (citable) accession number: A0A024RA97
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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