Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), isoform CRA_c

Gene

MPP6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), isoform CRA_cImported
Gene namesi
Name:MPP6Imported
ORF Names:hCG_38837Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000105926.15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024RA25

Expressioni

Gene expression databases

BgeeiENSG00000105926
ExpressionAtlasiA0A024RA25 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A024RA25
SMRiA0A024RA25
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 48L27InterPro annotationAdd BLAST48
Domaini49 – 107L27InterPro annotationAdd BLAST59
Domaini130 – 209PDZInterPro annotationAdd BLAST80
Domaini215 – 284SH3InterPro annotationAdd BLAST70
Domaini338 – 525Guanylate kinase-likeInterPro annotationAdd BLAST188

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili510 – 530Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the MAGUK family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0609 Eukaryota
COG0194 LUCA
OMAiDTIIPQQ
OrthoDBiEOG091G065I
PhylomeDBiA0A024RA25

Family and domain databases

CDDicd12038 SH3_MPP6, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR014775 L27_C
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR035603 MPP6_SH3
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF02828 L27, 2 hits
PF00595 PDZ, 1 hit
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM00569 L27, 2 hits
SM00228 PDZ, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF101288 SSF101288, 1 hit
SSF50044 SSF50044, 1 hit
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS51022 L27, 2 hits
PS50106 PDZ, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024RA25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQVLENLTE LPSSTGAEEI DLIFLKGIME NPIVKSLAKA HERLEDSKLE
60 70 80 90 100
AVSDNNLELV NEILEDITPL INVDENVAEL VGILKEPHFQ SLLEAHDIVA
110 120 130 140 150
SKCYDSPPSS PEMNNSSINN QLLPVDAIRI LGIHKRAGEP LGVTFRVENN
160 170 180 190 200
DLVIARILHG GMIDRQGLLH VGDIIKEVNG HEVGNNPKEL QELLKNISGS
210 220 230 240 250
VTLKILPSYR DTITPQQVFV KCHFDYNPYN DNLIPCKEAG LKFSKGEILQ
260 270 280 290 300
IVNREDPNWW QASHVKEGGS AGLIPSQFLE EKRKAFVRRD WDNSGPFCGT
310 320 330 340 350
ISSKKKKKMM YLTTRNAEFD RHEIQIYEEV AKMPPFQRKT LVLIGAQGVG
360 370 380 390 400
RRSLKNRFIV LNPTRFGTTV PFTSRKPRED EKDGQAYKFV SRSEMEADIK
410 420 430 440 450
AGKYLEHGEY EGNLYGTKID SILEVVQTGR TCILDVNPQA LKVLRTSEFM
460 470 480 490 500
PYVVFIAAPE LETLRAMHKA VVDAGITTKL LTDSDLKKTV DESARIQRAY
510 520 530 540
NHYFDLIIIN DNLDKAFEKL QTAIEKLRME PQWVPISWVY
Length:540
Mass (Da):61,117
Last modified:July 9, 2014 - v1
Checksum:i86310E4F6AF632BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471073 Genomic DNA Translation: EAW93811.1
RefSeqiNP_001289966.1, NM_001303037.1
NP_057531.2, NM_016447.3
XP_006715801.1, XM_006715738.3
XP_006715802.1, XM_006715739.3
XP_006715803.1, XM_006715740.3
XP_011513727.1, XM_011515425.2
XP_016867804.1, XM_017012315.1
XP_016867805.1, XM_017012316.1
XP_016867806.1, XM_017012317.1
UniGeneiHs.533355
Hs.563501
Hs.594275

Genome annotation databases

GeneIDi51678
KEGGihsa:51678

Similar proteinsi

Entry informationi

Entry nameiA0A024RA25_HUMAN
AccessioniPrimary (citable) accession number: A0A024RA25
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: July 18, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health