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Protein
Submitted name:

Transmembrane protein 106B, isoform CRA_a

Gene

TMEM106B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transmembrane protein 106B, isoform CRA_aImported
Gene namesi
Name:TMEM106BImported
ORF Names:hCG_1639909Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000106460.18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei96 – 117HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiA0A024R9Z1

Expressioni

Gene expression databases

BgeeiENSG00000106460 Expressed in 233 organ(s), highest expression level in metanephros
ExpressionAtlasiA0A024R9Z1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R9Z1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEC7 Eukaryota
ENOG410ZX7B LUCA
OMAiMKQIDYM
OrthoDBiEOG091G0KDT
PhylomeDBiA0A024R9Z1

Family and domain databases

InterProiView protein in InterPro
IPR009790 DUF1356_TMEM106
PANTHERiPTHR28556 PTHR28556, 1 hit
PfamiView protein in Pfam
PF07092 DUF1356, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R9Z1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKSLSHLPL HSSKEDAYDG VTSENMRNGL VNSEVHNEDG RNGDVSQFPY
60 70 80 90 100
VEFTGRDSVT CPTCQGTGRI PRGQENQLVA LIPYSDQRLR PRRTKLYVMA
110 120 130 140 150
SVFVCLLLSG LAVFFLFPRS IDVKYIGVKS AYVSYDVQKR TIYLNITNTL
160 170 180 190 200
NITNNNYYSV EVENITAQVQ FSKTVIGKAR LNNITIIGPL DMKQIDYTVP
210 220 230 240 250
TVIAEEMSYM YDFCTLISIK VHNIVLMMQV TVTTTYFGHS EQISQERYQY
260 270
VDCGRNTTYQ LGQSEYLNVL QPQQ
Length:274
Mass (Da):31,127
Last modified:July 9, 2014 - v1
Checksum:i906C923986DC04E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471073 Genomic DNA Translation: EAW93642.1
RefSeqiNP_001127704.1, NM_001134232.1
NP_060844.2, NM_018374.3
XP_005249846.1, XM_005249789.1
UniGeneiHs.396358

Genome annotation databases

GeneIDi54664
KEGGihsa:54664

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471073 Genomic DNA Translation: EAW93642.1
RefSeqiNP_001127704.1, NM_001134232.1
NP_060844.2, NM_018374.3
XP_005249846.1, XM_005249789.1
UniGeneiHs.396358

3D structure databases

ProteinModelPortaliA0A024R9Z1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R9Z1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi54664
KEGGihsa:54664

Organism-specific databases

CTDi54664
EuPathDBiHostDB:ENSG00000106460.18

Phylogenomic databases

eggNOGiENOG410IEC7 Eukaryota
ENOG410ZX7B LUCA
OMAiMKQIDYM
OrthoDBiEOG091G0KDT
PhylomeDBiA0A024R9Z1

Miscellaneous databases

ChiTaRSiTMEM106B human
GenomeRNAii54664

Gene expression databases

BgeeiENSG00000106460 Expressed in 233 organ(s), highest expression level in metanephros
ExpressionAtlasiA0A024R9Z1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR009790 DUF1356_TMEM106
PANTHERiPTHR28556 PTHR28556, 1 hit
PfamiView protein in Pfam
PF07092 DUF1356, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R9Z1_HUMAN
AccessioniPrimary (citable) accession number: A0A024R9Z1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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