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Protein
Submitted name:

Vacuolar protein sorting protein 18, isoform CRA_d

Gene

VPS18

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Vacuolar protein sorting protein 18, isoform CRA_dImported
Gene namesi
Name:VPS18Imported
ORF Names:hCG_38959Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000104142.10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000104142 Expressed in 181 organ(s), highest expression level in tendon of biceps brachii

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini291 – 434Pep3_Vps18InterPro annotationAdd BLAST144
Repeati618 – 772CHCRPROSITE-ProRule annotationAdd BLAST155

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili809 – 843Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2034 Eukaryota
ENOG410XRSD LUCA
KOiK20181
OMAiDAWIEMG
OrthoDBiEOG091G01XI

Family and domain databases

InterProiView protein in InterPro
IPR000547 Clathrin_H-chain/VPS_repeat
IPR007810 Pep3_Vps18
PfamiView protein in Pfam
PF00637 Clathrin, 1 hit
PF05131 Pep3_Vps18, 1 hit
PROSITEiView protein in PROSITE
PS50236 CHCR, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R9R3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASILDEYEN SLSRSAVLQP GCPSVGIPHS GYVNAQLEKE VPIFTKQRID
60 70 80 90 100
FTPSERITSL VVSSNQLCMS LGKDTLLRID LGKANEPNHV ELGRKDDAKV
110 120 130 140 150
HKMFLDHTGS HLLIALSSTE VLYVNRNGQK VRPLARWKGQ LVESVGWNKA
160 170 180 190 200
LGTESSTGPI LVGTAQGHIF EAELSASEGG LFGPAPDLYF RPLYVLNEEG
210 220 230 240 250
GPAPVCSLEA ERGPDGRSFV IATTRQRLFQ FIGRAAEGAE AQGFSGLFAA
260 270 280 290 300
YTDHPPPFRE FPSNLGYSEL AFYTPKLRSA PRAFAWMMGD GVLYGALDCG
310 320 330 340 350
RPDSLLSEER VWEYPEGVGP GASPPLAIVL TQFHFLLLLA DRVEAVCTLT
360 370 380 390 400
GQVVLRDHFL EKFGPLKHMV KDSSTGQLWA YTERAVFRYH VQREARDVWR
410 420 430 440 450
TYLDMNRFDL AKEYCRERPD CLDTVLAREA DFCFRQRRYL ESARCYALTQ
460 470 480 490 500
SYFEEIALKF LEARQEEALA EFLQRKLASL KPAERTQATL LTTWLTELYL
510 520 530 540 550
SRLGALQGDP EALTLYRETK ECFRTFLSSP RHKEWLFASR ASIHELLASH
560 570 580 590 600
GDTEHMVYFA VIMQDYERVV AYHCQHEAYE EALAVLARHR DPQLFYKFSP
610 620 630 640 650
ILIRHIPRQL VDAWIEMGSR LDARQLIPAL VNYSQGGEVQ QVSQAIRYME
660 670 680 690 700
FCVNVLGETE QAIHNYLLSL YARGRPDSLL AYLEQAGASP HRVHYDLKYA
710 720 730 740 750
LRLCAEHGHH RACVHVYKVL ELYEEAVDLA LQVDVDLAKQ CADLPEEDEE
760 770 780 790 800
LRKKLWLKIA RHVVQEEEDV QTAMACLASC PLLKIEDVLP FFPDFVTIDH
810 820 830 840 850
FKEAICSSLK AYNHHIQELQ REMEEATASA QRIRRDLQEL RGRYGTVEPQ
860 870 880 890 900
DKCATCDFPL LNRPFYLFLC GHMFHADCLL QAVRPGLPAY KQARLEELQR
910 920 930 940 950
KLGAAPPPAK GSARAKEAEG GAATAGPSRE QLKADLDELV AAECVYCGEL
960 970
MIRSIDRPFI DPQRYEEEQL SWL
Length:973
Mass (Da):110,186
Last modified:July 9, 2014 - v1
Checksum:i0008E21D66E8CFEC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471125 Genomic DNA Translation: EAW92464.1
CH471125 Genomic DNA Translation: EAW92465.1
RefSeqiNP_065908.1, NM_020857.2
UniGeneiHs.23876

Genome annotation databases

GeneIDi57617
KEGGihsa:57617

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471125 Genomic DNA Translation: EAW92464.1
CH471125 Genomic DNA Translation: EAW92465.1
RefSeqiNP_065908.1, NM_020857.2
UniGeneiHs.23876

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi57617
KEGGihsa:57617

Organism-specific databases

CTDi57617
EuPathDBiHostDB:ENSG00000104142.10

Phylogenomic databases

eggNOGiKOG2034 Eukaryota
ENOG410XRSD LUCA
KOiK20181
OMAiDAWIEMG
OrthoDBiEOG091G01XI

Miscellaneous databases

ChiTaRSiVPS18 human
GenomeRNAii57617

Gene expression databases

BgeeiENSG00000104142 Expressed in 181 organ(s), highest expression level in tendon of biceps brachii

Family and domain databases

InterProiView protein in InterPro
IPR000547 Clathrin_H-chain/VPS_repeat
IPR007810 Pep3_Vps18
PfamiView protein in Pfam
PF00637 Clathrin, 1 hit
PF05131 Pep3_Vps18, 1 hit
PROSITEiView protein in PROSITE
PS50236 CHCR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R9R3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R9R3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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