UniProtKB - A0A024R9M9 (A0A024R9M9_HUMAN)
Protein
Submitted name:
Calcium binding protein P22, isoform CRA_a
Gene
CHP
Organism
Homo sapiens (Human)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- calcium ion binding Source: Ensembl
- kinase binding Source: Ensembl
- microtubule binding Source: Ensembl
GO - Biological processi
- cytoplasmic microtubule organization Source: Ensembl
- membrane docking Source: Ensembl
- microtubule bundle formation Source: Ensembl
- negative regulation of protein autophosphorylation Source: Ensembl
- negative regulation of protein kinase activity Source: Ensembl
- negative regulation of protein ubiquitination Source: Ensembl
- positive regulation of protein glycosylation Source: Ensembl
- positive regulation of protein transport Source: Ensembl
- protein complex oligomerization Source: Ensembl
- protein export from nucleus Source: Ensembl
- protein stabilization Source: Ensembl
- vesicle fusion Source: Ensembl
- vesicle targeting Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Calcium binding protein P22, isoform CRA_aImported |
Gene namesi | Name:CHPImported ORF Names:hCG_1998669Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000187446.11 |
Subcellular locationi
Cytoskeleton
- microtubule cytoskeleton Source: Ensembl
Cytosol
- cytosol Source: Ensembl
Endoplasmic reticulum
- endoplasmic reticulum Source: Ensembl
Golgi apparatus
- Golgi membrane Source: Ensembl
Nucleus
- nucleus Source: Ensembl
Plasma Membrane
- plasma membrane Source: Ensembl
Other locations
- transport vesicle Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSG00000187446, Expressed in colon and 243 other tissues |
ExpressionAtlasi | A0A024R9M9, baseline and differential |
Interactioni
GO - Molecular functioni
- kinase binding Source: Ensembl
- microtubule binding Source: Ensembl
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 26 – 61 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 110 – 145 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 151 – 186 | EF-handInterPro annotationAdd BLAST | 36 |
Phylogenomic databases
HOGENOMi | CLU_061288_10_5_1 |
OMAi | HSFFADS |
OrthoDBi | 1271942at2759 |
Family and domain databases
CDDi | cd00051, EFh, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR002048, EF_hand_dom |
Pfami | View protein in Pfam PF13499, EF-hand_7, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 2 hits |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS50222, EF_HAND_2, 3 hits |
i Sequence
Sequence statusi: Complete.
A0A024R9M9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSRASTLLR DEELEEIKKE TGFSHSQITR LYSRFTSLDK GENGTLSRED
60 70 80 90 100
FQRIPELAIN PLGDRIINAF FPEGEDQVNF RGFMRTLAHF RPIEDNEKSK
110 120 130 140 150
DVNGPEPLNS RSNKLHFAFR LYDLDKDEKI SRDELLQVLR MMVGVNISDE
160 170 180 190
QLGSIADRTI QEADQDGDSA ISFTEFVKVL EKVDVEQKMS IRFLH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471125 Genomic DNA Translation: EAW92476.1 CH471125 Genomic DNA Translation: EAW92477.1 |
RefSeqi | NP_009167.1, NM_007236.4 |
Genome annotation databases
GeneIDi | 11261 |
KEGGi | hsa:11261 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471125 Genomic DNA Translation: EAW92476.1 CH471125 Genomic DNA Translation: EAW92477.1 |
RefSeqi | NP_009167.1, NM_007236.4 |
3D structure databases
SMRi | A0A024R9M9 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 1886, 220 antibodies |
Genome annotation databases
GeneIDi | 11261 |
KEGGi | hsa:11261 |
Organism-specific databases
CTDi | 11261 |
VEuPathDBi | HostDB:ENSG00000187446.11 |
Phylogenomic databases
HOGENOMi | CLU_061288_10_5_1 |
OMAi | HSFFADS |
OrthoDBi | 1271942at2759 |
Miscellaneous databases
BioGRID-ORCSi | 11261, 39 hits in 872 CRISPR screens |
GenomeRNAii | 11261 |
Gene expression databases
Bgeei | ENSG00000187446, Expressed in colon and 243 other tissues |
ExpressionAtlasi | A0A024R9M9, baseline and differential |
Family and domain databases
CDDi | cd00051, EFh, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR002048, EF_hand_dom |
Pfami | View protein in Pfam PF13499, EF-hand_7, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 2 hits |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS50222, EF_HAND_2, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R9M9_HUMAN | |
Accessioni | A0A024R9M9Primary (citable) accession number: A0A024R9M9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | February 10, 2021 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |