UniProtKB - A0A024R9C8 (A0A024R9C8_HUMAN)
Protein
Submitted name:
Tumor protein p53 inducible nuclear protein 1, isoform CRA_b
Gene
TP53INP1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- antioxidant activity Source: Ensembl
GO - Biological processi
- cell cycle arrest Source: Ensembl
- cellular response to ethanol Source: Ensembl
- cellular response to hydroperoxide Source: Ensembl
- cellular response to methyl methanesulfonate Source: Ensembl
- cellular response to UV Source: Ensembl
- negative regulation of cell migration Source: Ensembl
- negative regulation of fibroblast proliferation Source: Ensembl
- negative regulation of gene expression Source: Ensembl
- negative regulation of myofibroblast differentiation Source: Ensembl
- positive regulation of apoptotic process Source: Ensembl
- positive regulation of gene expression Source: Ensembl
- regulation of autophagy Source: InterPro
- regulation of transcription, DNA-templated Source: InterPro
- response to heat Source: Ensembl
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Tumor protein p53 inducible nuclear protein 1, isoform CRA_bImported |
Gene namesi | Name:TP53INP1Imported ORF Names:hCG_15935Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000164938.13 |
Subcellular locationi
Cytosol
- cytosol ARBA annotation
Nucleus
- PML body ARBA annotation
Other locations
- autophagosome ARBA annotation
Cytosol
- cytosol Source: HPA
Nucleus
- PML body Source: UniProtKB-SubCell
Other locations
- autophagosome Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmARBA annotation, NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000164938, Expressed in female gonad and 216 other tissues |
ExpressionAtlasi | A0A024R9C8, baseline and differential |
Family & Domainsi
Phylogenomic databases
HOGENOMi | CLU_091034_1_0_1 |
OMAi | DCHSRQI |
PhylomeDBi | A0A024R9C8 |
Family and domain databases
InterProi | View protein in InterPro IPR029431, TP53INP IPR029556, TP53INP1 |
PANTHERi | PTHR31671, PTHR31671, 1 hit PTHR31671:SF0, PTHR31671:SF0, 1 hit |
Pfami | View protein in Pfam PF14839, DOR, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A024R9C8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFQRLNKMFV GEVSSSSNQE PEFNEKEDDE WILVDFIDTC TGFSAEEEEE
60 70 80 90 100
EEDISEESPT EHPSVFSCLP ASLECLADTS DSCFLQFESC PMEESWFITP
110 120 130 140 150
PPCFTAGGLT TIKVETSPME NLLIEHPSMS VYAVHNSCPG LSEATRGTDE
160 170 180 190 200
LHSPSSPRVE AQNEMGQHIH CYVAALAAHT TFLEQPKSFR PSQWIKEHSE
210 220 230 240
RQPLNRNSLR RQNLTRDCHP RQVKHNGWVV HQPCPRQYNY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471060 Genomic DNA Translation: EAW91741.1 |
RefSeqi | NP_150601.1, NM_033285.3 XP_011515688.1, XM_011517386.2 |
Genome annotation databases
GeneIDi | 94241 |
KEGGi | hsa:94241 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471060 Genomic DNA Translation: EAW91741.1 |
RefSeqi | NP_150601.1, NM_033285.3 XP_011515688.1, XM_011517386.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 12951, 337 antibodies |
Genome annotation databases
GeneIDi | 94241 |
KEGGi | hsa:94241 |
Organism-specific databases
CTDi | 94241 |
EuPathDBi | HostDB:ENSG00000164938.13 |
Phylogenomic databases
HOGENOMi | CLU_091034_1_0_1 |
OMAi | DCHSRQI |
PhylomeDBi | A0A024R9C8 |
Miscellaneous databases
BioGRID-ORCSi | 94241, 1 hit in 848 CRISPR screens |
ChiTaRSi | TP53INP1, human |
GenomeRNAii | 94241 |
Gene expression databases
Bgeei | ENSG00000164938, Expressed in female gonad and 216 other tissues |
ExpressionAtlasi | A0A024R9C8, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR029431, TP53INP IPR029556, TP53INP1 |
PANTHERi | PTHR31671, PTHR31671, 1 hit PTHR31671:SF0, PTHR31671:SF0, 1 hit |
Pfami | View protein in Pfam PF14839, DOR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R9C8_HUMAN | |
Accessioni | A0A024R9C8Primary (citable) accession number: A0A024R9C8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | December 2, 2020 | |
This is version 39 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |