Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Synaptotagmin II, isoform CRA_a

Gene

SYT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Synaptotagmin II, isoform CRA_aImported
Gene namesi
Name:SYT2Imported
ORF Names:hCG_31792Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000143858.11

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei63 – 84HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSG00000143858 Expressed in 122 organ(s), highest expression level in midbrain

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini153 – 242C2InterPro annotationAdd BLAST90
Domaini284 – 375C2InterPro annotationAdd BLAST92

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1028 Eukaryota
ENOG4111B9R LUCA
KOiK19902
OMAiKGAKNAM
OrthoDBiEOG091G0XMQ

Family and domain databases

Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001565 Synaptotagmin
IPR015428 Synaptotagmin1/2
PANTHERiPTHR10024:SF223 PTHR10024:SF223, 1 hit
PfamiView protein in Pfam
PF00168 C2, 2 hits
PRINTSiPR00360 C2DOMAIN
PR00399 SYNAPTOTAGMN
SMARTiView protein in SMART
SM00239 C2, 2 hits
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits

Sequencei

Sequence statusi: Complete.

A0A024R9B3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRNIFKRNQE PIVAPATTTA TMPIGPVDNS TESGGAGESQ EDMFAKLKEK
60 70 80 90 100
LFNEINKIPL PPWALIAIAV VAGLLLLTCC FCICKKCCCK KKKNKKEKGK
110 120 130 140 150
GMKNAMNMKD MKGGQDDDDA ETGLTEGEGE GEEEKEPENL GKLQFSLDYD
160 170 180 190 200
FQANQLTVGV LQAAELPALD MGGTSDPYVK VFLLPDKKKK YETKVHRKTL
210 220 230 240 250
NPAFNETFTF KVPYQELGGK TLVMAIYDFD RFSKHDIIGE VKVPMNTVDL
260 270 280 290 300
GQPIEEWRDL QGGEKEEPEK LGDICTSLRY VPTAGKLTVC ILEAKNLKKM
310 320 330 340 350
DVGGLSDPYV KIHLMQNGKR LKKKKTTVKK KTLNPYFNES FSFEIPFEQI
360 370 380 390 400
QKVQVVVTVL DYDKLGKNEA IGKIFVGSNA TGTELRHWSD MLANPRRPIA
410
QWHSLKPEEE VDALLGKNK
Length:419
Mass (Da):46,872
Last modified:July 9, 2014 - v1
Checksum:iBE3855E9CDE2D76E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471067 Genomic DNA Translation: EAW91429.1
CH471067 Genomic DNA Translation: EAW91430.1
RefSeqiNP_001129976.1, NM_001136504.1
NP_796376.2, NM_177402.4
XP_016855802.1, XM_017000313.1
UniGeneiHs.25422

Genome annotation databases

GeneIDi127833
KEGGihsa:127833

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471067 Genomic DNA Translation: EAW91429.1
CH471067 Genomic DNA Translation: EAW91430.1
RefSeqiNP_001129976.1, NM_001136504.1
NP_796376.2, NM_177402.4
XP_016855802.1, XM_017000313.1
UniGeneiHs.25422

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi127833
KEGGihsa:127833

Organism-specific databases

CTDi127833
EuPathDBiHostDB:ENSG00000143858.11

Phylogenomic databases

eggNOGiKOG1028 Eukaryota
ENOG4111B9R LUCA
KOiK19902
OMAiKGAKNAM
OrthoDBiEOG091G0XMQ

Miscellaneous databases

ChiTaRSiSYT2 human
GenomeRNAii127833

Gene expression databases

BgeeiENSG00000143858 Expressed in 122 organ(s), highest expression level in midbrain

Family and domain databases

Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001565 Synaptotagmin
IPR015428 Synaptotagmin1/2
PANTHERiPTHR10024:SF223 PTHR10024:SF223, 1 hit
PfamiView protein in Pfam
PF00168 C2, 2 hits
PRINTSiPR00360 C2DOMAIN
PR00399 SYNAPTOTAGMN
SMARTiView protein in SMART
SM00239 C2, 2 hits
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R9B3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R9B3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again