UniProtKB - A0A024R8X4 (A0A024R8X4_HUMAN)
Protein
Fe2OG dioxygenase domain-containing protein
Gene
FLJ22222
Organism
Homo sapiens (Human)
Status
Functioni
Cofactori
L-ascorbateARBA annotation
GO - Molecular functioni
- dioxygenase activity Source: UniProtKB-KW
- iron ion binding Source: InterPro
- L-ascorbic acid binding Source: InterPro
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Keywordsi
Molecular function | DioxygenaseARBA annotation, Oxidoreductase |
Ligand | IronARBA annotation, Metal-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Fe2OG dioxygenase domain-containing proteinInterPro annotation |
Gene namesi | Name:FLJ22222Imported ORF Names:hCG_1810979Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 183 – 285 | Fe2OG dioxygenaseInterPro annotationAdd BLAST | 103 |
Family and domain databases
InterProi | View protein in InterPro IPR039210, OGFOD3 IPR005123, Oxoglu/Fe-dep_dioxygenase IPR006620, Pro_4_hyd_alph |
PANTHERi | PTHR14650, PTHR14650, 1 hit |
Pfami | View protein in Pfam PF13640, 2OG-FeII_Oxy_3, 1 hit |
SMARTi | View protein in SMART SM00702, P4Hc, 1 hit |
PROSITEi | View protein in PROSITE PS51471, FE2OG_OXY, 1 hit |
i Sequence
Sequence statusi: Fragment.
A0A024R8X4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
STKKDRAPRE VQRLWQRPWL RTAGLGAGFV LTALLLWSSL GADDGVAEVL
60 70 80 90 100
ARRGEVVAGR FIEVPCSEDY DSHRRFEGCT PRKCGRGVTD VVITREEAER
110 120 130 140 150
IRSVAEKGLS LGGSDGGASI LDLHSGALSV GKHFVNLYRY FGDKIQNIFS
160 170 180 190 200
EEDFRLYREV RQKVQLTIAE AFGISASSLH LTKPTFFSRI NSTEARTAHD
210 220 230 240 250
EYWHAHVDKV TYGSFDYTSL LYLSNYLEDF GGGRFMFMEE GANKTVEPRA
260 270 280 290
GRVSFFTSGS ENLHRVEKVH WGTRYAITIA FSCNPDHGIE DPAFP
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471099 Genomic DNA Translation: EAW89769.1 CH471099 Genomic DNA Translation: EAW89770.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471099 Genomic DNA Translation: EAW89769.1 CH471099 Genomic DNA Translation: EAW89770.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | A0A024R8X4 |
Family and domain databases
InterProi | View protein in InterPro IPR039210, OGFOD3 IPR005123, Oxoglu/Fe-dep_dioxygenase IPR006620, Pro_4_hyd_alph |
PANTHERi | PTHR14650, PTHR14650, 1 hit |
Pfami | View protein in Pfam PF13640, 2OG-FeII_Oxy_3, 1 hit |
SMARTi | View protein in SMART SM00702, P4Hc, 1 hit |
PROSITEi | View protein in PROSITE PS51471, FE2OG_OXY, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R8X4_HUMAN | |
Accessioni | A0A024R8X4Primary (citable) accession number: A0A024R8X4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | October 7, 2020 | |
This is version 21 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |