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Protein
Submitted name:

Nuclear protein localization 4 homolog (S. cerevisiae), isoform CRA_a

Gene

NPLOC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear protein localization 4 homolog (S. cerevisiae), isoform CRA_aImported
Gene namesi
Name:NPLOC4Imported
ORF Names:hCG_1811524Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000182446.13

Expressioni

Gene expression databases

BgeeiENSG00000182446 Expressed in 220 organ(s), highest expression level in testis

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini226 – 363MPNInterPro annotationAdd BLAST138
Domaini580 – 608RanBP2-typeInterPro annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2834 Eukaryota
COG5100 LUCA
KOiK14015

Family and domain databases

CDDicd08061 MPN_NPL4, 1 hit
InterProiView protein in InterPro
IPR037518 MPN
IPR016563 Npl4
IPR007717 NPL4_C
IPR024682 Npl4_Ub-like_dom
IPR007716 NPL4_Zn-bd_put
IPR029071 Ubiquitin-like_domsf
IPR001876 Znf_RanBP2
IPR036443 Znf_RanBP2_sf
PfamiView protein in Pfam
PF05021 NPL4, 1 hit
PF11543 UN_NPL4, 1 hit
PF05020 zf-NPL4, 1 hit
PIRSFiPIRSF010052 Polyub_prc_Npl4, 1 hit
SMARTiView protein in SMART
SM00547 ZnF_RBZ, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
SSF90209 SSF90209, 1 hit
PROSITEiView protein in PROSITE
PS50249 MPN, 1 hit
PS01358 ZF_RANBP2_1, 1 hit
PS50199 ZF_RANBP2_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R8R4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAESIIIRVQ SPDGVKRITA TKRETAATFL KKVAKEFGFQ NNGFSVYINR
60 70 80 90 100
NKTGEITASS NKSLNLLKIK HGDLLFLFPS SLAGPSSEME TSVPPGFKVF
110 120 130 140 150
GAPNVVEDEI DQYLSKQDGK IYRSRDPQLC RHGPLGKCVH CVPLEPFDED
160 170 180 190 200
YLNHLEPPVK HMSFHAYIRK LTGGADKGKF VALENISCKI KSGCEGHLPW
210 220 230 240 250
PNGICTKCQP SAITLNRQKY RHVDNIMFEN HTVADRFLDF WRKTGNQHFG
260 270 280 290 300
YLYGRYTEHK DIPLGIRAEV AAIYEPPQIG TQNSLELLED PKAEVVDEIA
310 320 330 340 350
AKLGLRKVGW IFTDLVSEDT RKGTVRYSRN KDTYFLSSEE CITAGDFQNK
360 370 380 390 400
HPNMCRLSPD GHFGSKFVTA VATGGPDNQV HFEGYQVSNQ CMALVRDECL
410 420 430 440 450
LPCKDAPELG YAKESSSEQY VPDVFYKDVD KFGNEITQLA RPLPVEYLII
460 470 480 490 500
DITTTFPKDP VYTFSISQNP FPIENRDVLG ETQDFHSLAT YLSQNTSSVF
510 520 530 540 550
LDTISDFHLL LFLVTNEVMP LQDSISLLLE AVRTRNEELA QTWKRSEQWA
560 570 580 590 600
TIEQLCSTVG GQLPGLHEYG AVGGSTHTAT AAMWACQHCT FMNQPGTGHC

EMCSLPRT
Length:608
Mass (Da):68,120
Last modified:July 9, 2014 - v1
Checksum:i6ED6A0145F15C01D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471099 Genomic DNA Translation: EAW89661.1
CH471099 Genomic DNA Translation: EAW89662.1
RefSeqiNP_060391.2, NM_017921.3
UniGeneiHs.464333

Genome annotation databases

GeneIDi55666
KEGGihsa:55666

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471099 Genomic DNA Translation: EAW89661.1
CH471099 Genomic DNA Translation: EAW89662.1
RefSeqiNP_060391.2, NM_017921.3
UniGeneiHs.464333

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi55666
KEGGihsa:55666

Organism-specific databases

CTDi55666
EuPathDBiHostDB:ENSG00000182446.13

Phylogenomic databases

eggNOGiKOG2834 Eukaryota
COG5100 LUCA
KOiK14015

Miscellaneous databases

ChiTaRSiNPLOC4 human
GenomeRNAii55666

Gene expression databases

BgeeiENSG00000182446 Expressed in 220 organ(s), highest expression level in testis

Family and domain databases

CDDicd08061 MPN_NPL4, 1 hit
InterProiView protein in InterPro
IPR037518 MPN
IPR016563 Npl4
IPR007717 NPL4_C
IPR024682 Npl4_Ub-like_dom
IPR007716 NPL4_Zn-bd_put
IPR029071 Ubiquitin-like_domsf
IPR001876 Znf_RanBP2
IPR036443 Znf_RanBP2_sf
PfamiView protein in Pfam
PF05021 NPL4, 1 hit
PF11543 UN_NPL4, 1 hit
PF05020 zf-NPL4, 1 hit
PIRSFiPIRSF010052 Polyub_prc_Npl4, 1 hit
SMARTiView protein in SMART
SM00547 ZnF_RBZ, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
SSF90209 SSF90209, 1 hit
PROSITEiView protein in PROSITE
PS50249 MPN, 1 hit
PS01358 ZF_RANBP2_1, 1 hit
PS50199 ZF_RANBP2_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R8R4_HUMAN
AccessioniPrimary (citable) accession number: A0A024R8R4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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