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UniProtKB - A0A024R8D8 (A0A024R8D8_HUMAN)
Protein
Submitted name:
Progestagen-associated endometrial protein (Placental protein 14, pregnancy-associated endometrial alpha-2-globulin, alpha uterine protein), isoform CRA_d
Gene
PAEP
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Progestagen-associated endometrial protein (Placental protein 14, pregnancy-associated endometrial alpha-2-globulin, alpha uterine protein), isoform CRA_dImported |
Gene namesi | Name:PAEPImported ORF Names:hCG_28728Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000122133 |
Subcellular locationi
Extracellular region or secreted
- extracellular region Source: UniProtKB-KW
Keywords - Cellular componenti
SecretedARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5014214273 | 19 – 180 | Sequence analysisAdd BLAST | 162 |
Expressioni
Gene expression databases
Bgeei | ENSG00000122133, Expressed in decidua and 85 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 174 | Lipocln_cytosolic_FA-bd_domInterPro annotationAdd BLAST | 141 |
Sequence similaritiesi
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
OMAi | WEDNRCV |
OrthoDBi | 1551422at2759 |
Family and domain databases
Gene3Di | 2.40.128.20, 1 hit |
InterProi | View protein in InterPro IPR002447, Blactoglobulin IPR012674, Calycin IPR002345, Lipocalin IPR022272, Lipocalin_CS IPR000566, Lipocln_cytosolic_FA-bd_dom |
PANTHERi | PTHR11430, PTHR11430, 1 hit |
Pfami | View protein in Pfam PF00061, Lipocalin, 1 hit |
PRINTSi | PR01172, BLCTOGLOBULN |
SUPFAMi | SSF50814, SSF50814, 1 hit |
PROSITEi | View protein in PROSITE PS00213, LIPOCALIN, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A024R8D8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLCLLLTLGV ALVCGVPAMD IPQTKQDLEL PKLAGTWHSM AMATNNISLM
60 70 80 90 100
ATLKAPLRVH ITSLLPTPED NLEIVLHRWE NNSCVEKKVL GEKTENPKKF
110 120 130 140 150
KINYTVANEA TLLDTDYDNF LFLCLQDTTT PIQSMMCQYL ARVLVEDDEI
160 170 180
MQGFIRAFRP LPRHLWYLLD LKQMEEPCRF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471090 Genomic DNA Translation: EAW88166.1 CH471090 Genomic DNA Translation: EAW88167.1 CH471090 Genomic DNA Translation: EAW88168.1 |
RefSeqi | NP_001018059.1, NM_001018049.2 NP_002562.2, NM_002571.3 XP_011517051.1, XM_011518749.2 |
Genome annotation databases
GeneIDi | 5047 |
KEGGi | hsa:5047 |
MANE-Selecti | ENST00000479141.6; ENSP00000417898.1; NM_002571.4; NP_002562.2 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471090 Genomic DNA Translation: EAW88166.1 CH471090 Genomic DNA Translation: EAW88167.1 CH471090 Genomic DNA Translation: EAW88168.1 |
RefSeqi | NP_001018059.1, NM_001018049.2 NP_002562.2, NM_002571.3 XP_011517051.1, XM_011518749.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 3391, 383 antibodies from 30 providers |
DNASUi | 5047 |
Genome annotation databases
GeneIDi | 5047 |
KEGGi | hsa:5047 |
MANE-Selecti | ENST00000479141.6; ENSP00000417898.1; NM_002571.4; NP_002562.2 |
Organism-specific databases
CTDi | 5047 |
VEuPathDBi | HostDB:ENSG00000122133 |
Phylogenomic databases
OMAi | WEDNRCV |
OrthoDBi | 1551422at2759 |
Miscellaneous databases
BioGRID-ORCSi | 5047, 10 hits in 1035 CRISPR screens |
ChiTaRSi | PAEP, human |
GenomeRNAii | 5047 |
Gene expression databases
Bgeei | ENSG00000122133, Expressed in decidua and 85 other tissues |
Family and domain databases
Gene3Di | 2.40.128.20, 1 hit |
InterProi | View protein in InterPro IPR002447, Blactoglobulin IPR012674, Calycin IPR002345, Lipocalin IPR022272, Lipocalin_CS IPR000566, Lipocln_cytosolic_FA-bd_dom |
PANTHERi | PTHR11430, PTHR11430, 1 hit |
Pfami | View protein in Pfam PF00061, Lipocalin, 1 hit |
PRINTSi | PR01172, BLCTOGLOBULN |
SUPFAMi | SSF50814, SSF50814, 1 hit |
PROSITEi | View protein in PROSITE PS00213, LIPOCALIN, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R8D8_HUMAN | |
Accessioni | A0A024R8D8Primary (citable) accession number: A0A024R8D8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | January 19, 2022 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |