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Protein
Submitted name:

Caspase recruitment domain family, member 11, isoform CRA_a

Gene

CARD11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase recruitment domain family, member 11, isoform CRA_aImported
Gene namesi
Name:CARD11Imported
ORF Names:hCG_18438Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000198286.9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000198286 Expressed in 159 organ(s), highest expression level in leukocyte

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 110CARDInterPro annotationAdd BLAST93

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili222 – 256Sequence analysisAdd BLAST35
Coiled coili262 – 289Sequence analysisAdd BLAST28
Coiled coili302 – 350Sequence analysisAdd BLAST49
Coiled coili358 – 448Sequence analysisAdd BLAST91

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410ISRJ Eukaryota
ENOG41126VR LUCA
KOiK07367
OMAiEACIVNL
OrthoDBiEOG091G0T58

Family and domain databases

InterProiView protein in InterPro
IPR001315 CARD
IPR033538 CARD11
IPR011029 DEATH-like_dom_sf
IPR027417 P-loop_NTPase
IPR036034 PDZ_sf
PANTHERiPTHR14559:SF4 PTHR14559:SF4, 1 hit
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R854-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGGGPEMDD YMETLKDEED ALWENVECNR HMLSRYINPA KLTPYLRQCK
60 70 80 90 100
VIDEQDEDEV LNAPMLPSKI NRAGRLLDIL HTKGQRGYVV FLESLEFYYP
110 120 130 140 150
ELYKLVTGKE PTRRFSTIVV EEGHEGLTHF LMNEVIKLQQ QMKAKDLQRC
160 170 180 190 200
ELLARLRQLE DEKKQMTLTR VELLTFQERY YKMKEERDSY NDELVKVKDD
210 220 230 240 250
NYNLAMRYAQ LSEEKNMAVM RSRDLQLEID QLKHRLNKME EECKLERNQS
260 270 280 290 300
LKLKNDIENR PKKEQVLELE RENEMLKTKN QELQSIIQAG KRSLPDSDKA
310 320 330 340 350
ILDILEHDRK EALEDRQELV NRIYNLQEEA RQAEELRDKY LEEKEDLELK
360 370 380 390 400
CSTLGKDCEM YKHRMNTVML QLEEVERERD QAFHSRDEAQ TQYSQCLIEK
410 420 430 440 450
DKYRKQIREL EEKNDEMRIE MVRREACIVN LESKLRRLSK DSNNLDQSLP
460 470 480 490 500
RNLPVTIISQ DFGDASPRTN GQEADDSSTS EESPEDSKYF LPYHPPQRRM
510 520 530 540 550
NLKGIQLQRA KSPISLKRTS DFQAKGHEEE GTDASPSSCG SLPITNSFTK
560 570 580 590 600
MQPPRSRSSI MSITAEPPGN DSIVRRYKED APHRSTVEED NDSGGFDALD
610 620 630 640 650
LDDDSHERYS FGPSSIHSSS SSHQSEGLDA YDLEQVNLMF RKFSLERPFR
660 670 680 690 700
PSVTSVGHVR GPGPSVQHTT LNGDSLTSQL TLLGGNARGS FVHSVKPGSL
710 720 730 740 750
AEKAGLREGH QLLLLEGCIR GERQSVPLDT CTKEEAHWTI QRCSGPVTLH
760 770 780 790 800
YKVNHEGYRK LVKDMEDGLI TSGDSFYIRL NLNISSQLDA CTMSLKCDDV
810 820 830 840 850
VHVRDTMYQD RHEWLCARVD PFTDHDLDMG TIPSYSRAQQ LLLVKLQRLM
860 870 880 890 900
HRGSREEVDG THHTLRALRN TLQPEEALST SDPRVSPRLS RASFLFGQLL
910 920 930 940 950
QFVSRSENKY KRMNSNERVR IISGSPLGSL ARSSLDATKL LTEKQEELDP
960 970 980 990 1000
ESELGKNLSL IPYSLVRAFY CERRRPVLFT PTVLAKTLVQ RLLNSGGAME
1010 1020 1030 1040 1050
FTICKSDIVT RDEFLRRQKT ETIIYSREKN PNAFECIAPA NIEAVAAKNK
1060 1070 1080 1090 1100
HCLLEAGIGC TRDLIKSNIY PIVLFIRVCE KNIKRFRKLL PRPETEEEFL
1110 1120 1130 1140 1150
RVCRLKEKEL EALPCLYATV EPDMWGSVEE LLRVVKDKIG EEQRKTIWVD

EDQL
Length:1,154
Mass (Da):133,284
Last modified:July 9, 2014 - v1
Checksum:i2F3512D903795D18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471144 Genomic DNA Translation: EAW87276.1
CH471144 Genomic DNA Translation: EAW87279.1
RefSeqiNP_001311210.1, NM_001324281.1
NP_115791.3, NM_032415.5
XP_011513888.1, XM_011515586.2
UniGeneiHs.648101

Genome annotation databases

GeneIDi84433
KEGGihsa:84433

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471144 Genomic DNA Translation: EAW87276.1
CH471144 Genomic DNA Translation: EAW87279.1
RefSeqiNP_001311210.1, NM_001324281.1
NP_115791.3, NM_032415.5
XP_011513888.1, XM_011515586.2
UniGeneiHs.648101

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi84433
KEGGihsa:84433

Organism-specific databases

CTDi84433
EuPathDBiHostDB:ENSG00000198286.9

Phylogenomic databases

eggNOGiENOG410ISRJ Eukaryota
ENOG41126VR LUCA
KOiK07367
OMAiEACIVNL
OrthoDBiEOG091G0T58

Miscellaneous databases

ChiTaRSiCARD11 human
GenomeRNAii84433

Gene expression databases

BgeeiENSG00000198286 Expressed in 159 organ(s), highest expression level in leukocyte

Family and domain databases

InterProiView protein in InterPro
IPR001315 CARD
IPR033538 CARD11
IPR011029 DEATH-like_dom_sf
IPR027417 P-loop_NTPase
IPR036034 PDZ_sf
PANTHERiPTHR14559:SF4 PTHR14559:SF4, 1 hit
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R854_HUMAN
AccessioniPrimary (citable) accession number: A0A024R854
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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