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Protein

cAMP-dependent protein kinase inhibitor

Gene

PKIA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei16Important for inhibitionUniRule annotation1
Sitei19Important for inhibitionUniRule annotation1
Sitei20Important for inhibitionUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Protein kinase inhibitorUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
cAMP-dependent protein kinase inhibitorUniRule annotation
Gene namesi
Name:PKIAImported
ORF Names:hCG_19926Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000171033.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000171033 Expressed in 215 organ(s), highest expression level in biceps brachii

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the PKI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410J11W Eukaryota
ENOG410YT4B LUCA
KOiK15985
OMAiCGYLLAM
OrthoDBiEOG091G0LVC

Family and domain databases

InterProiView protein in InterPro
IPR004171 cAMP_dep_PKI
PANTHERiPTHR15416 PTHR15416, 1 hit
PfamiView protein in Pfam
PF02827 PKI, 1 hit
PIRSFiPIRSF001667 PKI, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD010366 cAMP_dep_PKI, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R7Y9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDVETTYAD FIASGRTGRR NAIHDILVSS ASGNSNELAL KLAGLDINKT
60 70
EGEEDAQRSS TEQSGEAQGE AAKSES
Length:76
Mass (Da):7,989
Last modified:July 9, 2014 - v1
Checksum:iBDCE072810435951
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471068 Genomic DNA Translation: EAW87055.1
CH471068 Genomic DNA Translation: EAW87056.1
CH471068 Genomic DNA Translation: EAW87057.1
CH471068 Genomic DNA Translation: EAW87058.1
RefSeqiNP_006814.1, NM_006823.3
NP_862822.1, NM_181839.2
XP_016869109.1, XM_017013620.1
XP_016869110.1, XM_017013621.1
XP_016869111.1, XM_017013622.1
UniGeneiHs.433700
Hs.732129

Genome annotation databases

GeneIDi5569
KEGGihsa:5569

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471068 Genomic DNA Translation: EAW87055.1
CH471068 Genomic DNA Translation: EAW87056.1
CH471068 Genomic DNA Translation: EAW87057.1
CH471068 Genomic DNA Translation: EAW87058.1
RefSeqiNP_006814.1, NM_006823.3
NP_862822.1, NM_181839.2
XP_016869109.1, XM_017013620.1
XP_016869110.1, XM_017013621.1
XP_016869111.1, XM_017013622.1
UniGeneiHs.433700
Hs.732129

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5569
KEGGihsa:5569

Organism-specific databases

CTDi5569
EuPathDBiHostDB:ENSG00000171033.12

Phylogenomic databases

eggNOGiENOG410J11W Eukaryota
ENOG410YT4B LUCA
KOiK15985
OMAiCGYLLAM
OrthoDBiEOG091G0LVC

Miscellaneous databases

ChiTaRSiPKIA human
GenomeRNAii5569

Gene expression databases

BgeeiENSG00000171033 Expressed in 215 organ(s), highest expression level in biceps brachii

Family and domain databases

InterProiView protein in InterPro
IPR004171 cAMP_dep_PKI
PANTHERiPTHR15416 PTHR15416, 1 hit
PfamiView protein in Pfam
PF02827 PKI, 1 hit
PIRSFiPIRSF001667 PKI, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD010366 cAMP_dep_PKI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R7Y9_HUMAN
AccessioniPrimary (citable) accession number: A0A024R7Y9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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