Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Clathrin light chain

Gene

CLTB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Clathrin light chainUniRule annotation
Gene namesi
Name:CLTBImported
ORF Names:hCG_40284Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000175416.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Coated pitUniRule annotation, Cytoplasmic vesicleUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PRIDEiA0A024R7S3

Expressioni

Gene expression databases

BgeeiENSG00000175416 Expressed in 227 organ(s), highest expression level in esophagus mucosa
ExpressionAtlasiA0A024R7S3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R7S3
SMRiA0A024R7S3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili107 – 127Sequence analysisAdd BLAST21
Coiled coili129 – 149Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the clathrin light chain family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR000996 Clathrin_L-chain
PANTHERiPTHR10639 PTHR10639, 1 hit
PfamiView protein in Pfam
PF01086 Clathrin_lg_ch, 1 hit
PROSITEiView protein in PROSITE
PS00224 CLATHRIN_LIGHT_CHN_1, 1 hit
PS00581 CLATHRIN_LIGHT_CHN_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R7S3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADDFGFFSS SESGAPEAAE EDPAAAFLAQ QESEIAGIEN DEGFGAPAGS
60 70 80 90 100
HAAPAQPGPT SGAGSEDMGT TVNGDVFQEA NGPADGYAAI AQADRLTQEP
110 120 130 140 150
ESIRKWREEQ RKRLQELDAA SKVTEQEWRE KAKKDLEEWN QRQSEQVEKN
160 170 180 190 200
KINNRASEEA FVKESKEETP GTEWEKVAQL CDFNPKSSKQ CKDVSRLRSV
210
LMSLKQTPLS R
Length:211
Mass (Da):23,181
Last modified:July 9, 2014 - v1
Checksum:i5B40F043E1809238
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471195 Genomic DNA Translation: EAW85080.1
RefSeqiNP_001825.1, NM_001834.3
UniGeneiHs.484241

Genome annotation databases

GeneIDi1212

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471195 Genomic DNA Translation: EAW85080.1
RefSeqiNP_001825.1, NM_001834.3
UniGeneiHs.484241

3D structure databases

ProteinModelPortaliA0A024R7S3
SMRiA0A024R7S3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R7S3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1212

Organism-specific databases

CTDi1212
EuPathDBiHostDB:ENSG00000175416.12

Miscellaneous databases

ChiTaRSiCLTB human
GenomeRNAii1212

Gene expression databases

BgeeiENSG00000175416 Expressed in 227 organ(s), highest expression level in esophagus mucosa
ExpressionAtlasiA0A024R7S3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000996 Clathrin_L-chain
PANTHERiPTHR10639 PTHR10639, 1 hit
PfamiView protein in Pfam
PF01086 Clathrin_lg_ch, 1 hit
PROSITEiView protein in PROSITE
PS00224 CLATHRIN_LIGHT_CHN_1, 1 hit
PS00581 CLATHRIN_LIGHT_CHN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R7S3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R7S3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again