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Protein
Submitted name:

Zinc finger protein 43 (HTF6), isoform CRA_a

Gene

ZNF43

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 43 (HTF6), isoform CRA_aImported
Gene namesi
Name:ZNF43Imported
ORF Names:hCG_36737Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000198521.11

Subcellular locationi

PTM / Processingi

Proteomic databases

PRIDEiA0A024R7P7

Expressioni

Gene expression databases

BgeeiENSG00000198521 Expressed in 226 organ(s), highest expression level in lung
ExpressionAtlasiA0A024R7P7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R7P7
SMRiA0A024R7P7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 69KRABInterPro annotationAdd BLAST69
Domaini168 – 191C2H2-typeInterPro annotationAdd BLAST24
Domaini196 – 223C2H2-typeInterPro annotationAdd BLAST28
Domaini224 – 251C2H2-typeInterPro annotationAdd BLAST28
Domaini252 – 279C2H2-typeInterPro annotationAdd BLAST28
Domaini280 – 307C2H2-typeInterPro annotationAdd BLAST28
Domaini308 – 335C2H2-typeInterPro annotationAdd BLAST28
Domaini336 – 363C2H2-typeInterPro annotationAdd BLAST28
Domaini364 – 391C2H2-typeInterPro annotationAdd BLAST28
Domaini392 – 419C2H2-typeInterPro annotationAdd BLAST28
Domaini420 – 447C2H2-typeInterPro annotationAdd BLAST28
Domaini448 – 475C2H2-typeInterPro annotationAdd BLAST28
Domaini476 – 503C2H2-typeInterPro annotationAdd BLAST28
Domaini504 – 531C2H2-typeInterPro annotationAdd BLAST28
Domaini532 – 559C2H2-typeInterPro annotationAdd BLAST28
Domaini560 – 587C2H2-typeInterPro annotationAdd BLAST28
Domaini588 – 615C2H2-typeInterPro annotationAdd BLAST28
Domaini616 – 643C2H2-typeInterPro annotationAdd BLAST28
Domaini644 – 671C2H2-typeInterPro annotationAdd BLAST28
Domaini672 – 699C2H2-typeInterPro annotationAdd BLAST28
Domaini700 – 727C2H2-typeInterPro annotationAdd BLAST28
Domaini728 – 755C2H2-typeInterPro annotationAdd BLAST28
Domaini756 – 783C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 19 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 22 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 12 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 19 hits
PS50157 ZINC_FINGER_C2H2_2, 22 hits

Sequencei

Sequence statusi: Complete.

A0A024R7P7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVAIEFCLE EWQCLDIAQQ NLYRNVMLEN YRNLVFLGIA VSKPDLITCL
60 70 80 90 100
EQEKEPWEPM RRHEMVAKPP VMCSHFTQDF WPEQHIKDPF QKATLRRYKN
110 120 130 140 150
CEHKNVHLKK DHKSVDECKV HRGGYNGFNQ CLPATQSKIF LFDKCVKAFH
160 170 180 190 200
KFSNSNRHKI SHTEKKLFKC KECGKSFCML PHLAQHKIIH TRVNFCKCEK
210 220 230 240 250
CGKAFNCPSI ITKHKRINTG EKPYTCEECG KVFNWSSRLT THKKNYTRYK
260 270 280 290 300
LYKCEECGKA FNKSSILTTH KIIRTGEKFY KCKECAKAFN QSSNLTEHKK
310 320 330 340 350
IHPGEKPYKC EECGKAFNWP STLTKHKRIH TGEKPYTCEE CGKAFNQFSN
360 370 380 390 400
LTTHKRIHTA EKFYKCTECG EAFSRSSNLT KHKKIHTEKK PYKCEECGKA
410 420 430 440 450
FKWSSKLTEH KLTHTGEKPY KCEECGKAFN WPSTLTKHNR IHTGEKPYKC
460 470 480 490 500
EVCGKAFNQF SNLTTHKRIH TAEKPYKCEE CGKAFSRSSN LTKHKKIHIE
510 520 530 540 550
KKPYKCEECG KAFKWSSKLT EHKITHTGEK PYKCEECGKA FNHFSILTKH
560 570 580 590 600
KRIHTGEKPY KCEECGKAFT QSSNLTTHKK IHTGEKFYKC EECGKAFTQS
610 620 630 640 650
SNLTTHKKIH TGGKPYKCEE CGKAFNQFST LTKHKIIHTE EKPYKCEECG
660 670 680 690 700
KAFKWSSTLT KHKIIHTGEK PYKCEECGKA FKLSSTLSTH KIIHTGEKPY
710 720 730 740 750
KCEKCGKAFN RSSNLIEHKK IHTGEQPYKC EECGKAFNYS SHLNTHKRIH
760 770 780 790 800
TKEQPYKCKE CGKAFNQYSN LTTHNKIHTG EKLYKPEDVT VILTTPQTFS

NIK
Length:803
Mass (Da):93,478
Last modified:July 9, 2014 - v1
Checksum:i8A3BCB47ECDD1500
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471106 Genomic DNA Translation: EAW84909.1
RefSeqiNP_001243577.1, NM_001256648.1
NP_001243578.1, NM_001256649.1
NP_001243579.1, NM_001256650.1
XP_011526559.1, XM_011528257.2
XP_011526561.1, XM_011528259.2
XP_016882696.1, XM_017027207.1
XP_016882697.1, XM_017027208.1
XP_016882698.1, XM_017027209.1
XP_016882699.1, XM_017027210.1
XP_016882700.1, XM_017027211.1
XP_016882701.1, XM_017027212.1
XP_016882702.1, XM_017027213.1
XP_016882703.1, XM_017027214.1
XP_016882704.1, XM_017027215.1
XP_016882705.1, XM_017027216.1
UniGeneiHs.534365

Genome annotation databases

GeneIDi7594

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471106 Genomic DNA Translation: EAW84909.1
RefSeqiNP_001243577.1, NM_001256648.1
NP_001243578.1, NM_001256649.1
NP_001243579.1, NM_001256650.1
XP_011526559.1, XM_011528257.2
XP_011526561.1, XM_011528259.2
XP_016882696.1, XM_017027207.1
XP_016882697.1, XM_017027208.1
XP_016882698.1, XM_017027209.1
XP_016882699.1, XM_017027210.1
XP_016882700.1, XM_017027211.1
XP_016882701.1, XM_017027212.1
XP_016882702.1, XM_017027213.1
XP_016882703.1, XM_017027214.1
XP_016882704.1, XM_017027215.1
XP_016882705.1, XM_017027216.1
UniGeneiHs.534365

3D structure databases

ProteinModelPortaliA0A024R7P7
SMRiA0A024R7P7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R7P7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7594

Organism-specific databases

CTDi7594
EuPathDBiHostDB:ENSG00000198521.11

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA

Miscellaneous databases

ChiTaRSiZNF43 human
GenomeRNAii7594

Gene expression databases

BgeeiENSG00000198521 Expressed in 226 organ(s), highest expression level in lung
ExpressionAtlasiA0A024R7P7 baseline and differential

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 19 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 22 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 12 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 19 hits
PS50157 ZINC_FINGER_C2H2_2, 22 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R7P7_HUMAN
AccessioniPrimary (citable) accession number: A0A024R7P7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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