UniProtKB - A0A024R7L4 (A0A024R7L4_HUMAN)
Protein
Submitted name:
Chromosome 19 open reading frame 4, isoform CRA_a
Gene
C19orf4
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Chromosome 19 open reading frame 4, isoform CRA_aImported |
Gene namesi | Name:C19orf4Imported ORF Names:hCG_37045Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000105696.8 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 268 – 290 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | Sequence analysisAdd BLAST | 24 | |
ChainiPRO_5014214267 | 25 – 342 | Sequence analysisAdd BLAST | 318 |
Expressioni
Gene expression databases
Bgeei | ENSG00000105696, Expressed in anterior cingulate cortex and 156 other tissues |
ExpressionAtlasi | A0A024R7L4, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the TMEM59 family.ARBA annotation
Keywords - Domaini
SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
HOGENOMi | CLU_059747_0_0_1 |
OMAi | WSQNPEP |
OrthoDBi | 1102891at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR022065, Uncharacterised_TMEM59 |
PANTHERi | PTHR28652, PTHR28652, 1 hit |
Pfami | View protein in Pfam PF12280, BSMAP, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A024R7L4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAVALMPPP LLLLLLLASP PAASAPSARD PFAPQLGDTQ NCQLRCRDRD
60 70 80 90 100
LGPQPSQAGL EGASESPYDR AVLISACERG CRLFSICRFV ARSSKPNATQ
110 120 130 140 150
TECEAACVEA YVKEAEQQAC SHGCWSQPAE PEPEQKRKVL EAPSGALSLL
160 170 180 190 200
DLFSTLCNDL VNSAQGFVSS TWTYYLQTDN GKVVVFQTQP IVESLGFQGG
210 220 230 240 250
RLQRVEVTWR GSHPEALEVH VDPVGPLDKV RKAKIRVKTS SKAKVESEEP
260 270 280 290 300
QDNDFLSCMS RRSGLPRWIL ACCLFLSVLV MLWLSCSTLV TAPGQHLKFQ
310 320 330 340
PLTLEQHKGF MMEPDWPLYP PPSHACEDSL PPYKLKLDLT KL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471106 Genomic DNA Translation: EAW84726.1 CH471106 Genomic DNA Translation: EAW84727.1 |
RefSeqi | NP_036241.1, NM_012109.2 |
Genome annotation databases
GeneIDi | 25789 |
KEGGi | hsa:25789 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471106 Genomic DNA Translation: EAW84726.1 CH471106 Genomic DNA Translation: EAW84727.1 |
RefSeqi | NP_036241.1, NM_012109.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 2303, 108 antibodies |
Genome annotation databases
GeneIDi | 25789 |
KEGGi | hsa:25789 |
Organism-specific databases
CTDi | 25789 |
VEuPathDBi | HostDB:ENSG00000105696.8 |
Phylogenomic databases
HOGENOMi | CLU_059747_0_0_1 |
OMAi | WSQNPEP |
OrthoDBi | 1102891at2759 |
Miscellaneous databases
BioGRID-ORCSi | 25789, 3 hits in 872 CRISPR screens |
ChiTaRSi | TMEM59L, human |
GenomeRNAii | 25789 |
Gene expression databases
Bgeei | ENSG00000105696, Expressed in anterior cingulate cortex and 156 other tissues |
ExpressionAtlasi | A0A024R7L4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR022065, Uncharacterised_TMEM59 |
PANTHERi | PTHR28652, PTHR28652, 1 hit |
Pfami | View protein in Pfam PF12280, BSMAP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R7L4_HUMAN | |
Accessioni | A0A024R7L4Primary (citable) accession number: A0A024R7L4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | February 10, 2021 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |