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Protein
Submitted name:

RAB8A, member RAS oncogene family, isoform CRA_a

Gene

RAB8A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
RAB8A, member RAS oncogene family, isoform CRA_aImported
Gene namesi
Name:RAB8AImported
ORF Names:hCG_36928Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000167461.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024R7I3

Expressioni

Gene expression databases

BgeeiENSG00000167461 Expressed in 242 organ(s), highest expression level in liver
ExpressionAtlasiA0A024R7I3 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A024R7I3
SMRiA0A024R7I3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0078 Eukaryota
ENOG410XPUI LUCA
KOiK07901
OMAiHSFQNIR
PhylomeDBiA0A024R7I3

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R7I3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKTYDYLFK LLLIGDSGVG KTCVLFRFSE DAFNSTFIST IGIDFKIRTI
60 70 80 90 100
ELDGKRIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFDNIR
110 120 130 140 150
NWIRNIEEHA SADVEKMILG NKCDVNDKRQ VSKERGEKLA LDYGIKFMET
160 170 180 190 200
SAKANINVEN AFFTLARDIK AKMDKKLEGN SPQGSNQGVK ITPDQQKRSS

FFRCVLL
Length:207
Mass (Da):23,668
Last modified:July 9, 2014 - v1
Checksum:iAA52DBF54A2CD056
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471106 Genomic DNA Translation: EAW84527.1
RefSeqiNP_005361.2, NM_005370.4
UniGeneiHs.642874

Genome annotation databases

GeneIDi4218
KEGGihsa:4218

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471106 Genomic DNA Translation: EAW84527.1
RefSeqiNP_005361.2, NM_005370.4
UniGeneiHs.642874

3D structure databases

ProteinModelPortaliA0A024R7I3
SMRiA0A024R7I3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R7I3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4218
KEGGihsa:4218

Organism-specific databases

CTDi4218
EuPathDBiHostDB:ENSG00000167461.11

Phylogenomic databases

eggNOGiKOG0078 Eukaryota
ENOG410XPUI LUCA
KOiK07901
OMAiHSFQNIR
PhylomeDBiA0A024R7I3

Miscellaneous databases

ChiTaRSiRAB8A human
GenomeRNAii4218

Gene expression databases

BgeeiENSG00000167461 Expressed in 242 organ(s), highest expression level in liver
ExpressionAtlasiA0A024R7I3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R7I3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R7I3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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