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Protein
Submitted name:

Dynein, cytoplasmic 1, light intermediate chain 2, isoform CRA_a

Gene

DYNC1LI2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynein, cytoplasmic 1, light intermediate chain 2, isoform CRA_aImported
Gene namesi
Name:DYNC1LI2Imported
ORF Names:hCG_28828Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000135720.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024R6Z0

Expressioni

Gene expression databases

BgeeiENSG00000135720 Expressed in 246 organ(s), highest expression level in brain
ExpressionAtlasiA0A024R6Z0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R6Z0
SMRiA0A024R6Z0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3905 Eukaryota
ENOG410XQS4 LUCA
KOiK10416
OMAiFQDYIEP
OrthoDBiEOG091G0B3J
PhylomeDBiA0A024R6Z0

Family and domain databases

InterProiView protein in InterPro
IPR008467 Dynein1_light_intermed_chain
IPR022780 Dynein_light_int_chain
IPR027417 P-loop_NTPase
PANTHERiPTHR12688 PTHR12688, 1 hit
PfamiView protein in Pfam
PF05783 DLIC, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

Sequencei

Sequence statusi: Complete.

A0A024R6Z0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPVGVEKKL LLGPNGPAVA AAGDLTSEEE EGQSLWSSIL SEVSTRARSK
60 70 80 90 100
LPSGKNILVF GEDGSGKTTL MTKLQGAEHG KKGRGLEYLY LSVHDEDRDD
110 120 130 140 150
HTRCNVWILD GDLYHKGLLK FAVSAESLPE TLVIFVADMS RPWTVMESLQ
160 170 180 190 200
KWASVLREHI DKMKIPPEKM RELERKFVKD FQDYMEPEEG CQGSPQRRGP
210 220 230 240 250
LTSGSDEENV ALPLGDNVLT HNLGIPVLVV CTKCDAVSVL EKEHDYRDEH
260 270 280 290 300
LDFIQSHLRR FCLQYGAALI YTSVKEEKNL DLLYKYIVHK TYGFHFTTPA
310 320 330 340 350
LVVEKDAVFI PAGWDNEKKI AILHENFTTV KPEDAYEDFI VKPPVRKLVH
360 370 380 390 400
DKELAAEDEQ VFLMKQQSLL AKQPATPTRA SESPARGPSG SPRTQGRGGP
410 420 430 440 450
ASVPSSSPGT SVKKPDPNIK NNAASEGVLA SFFNSLLSKK TGSPGSPGAG
460 470 480 490
GVQSTAKKSG QKTVLSNVQE ELDRMTRKPD SMVTNSSTEN EA
Length:492
Mass (Da):54,099
Last modified:July 9, 2014 - v1
Checksum:iAF7B4E49E3983DCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471092 Genomic DNA Translation: EAW83040.1
RefSeqiNP_006132.1, NM_006141.2
UniGeneiHs.369068

Genome annotation databases

GeneIDi1783
KEGGihsa:1783

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471092 Genomic DNA Translation: EAW83040.1
RefSeqiNP_006132.1, NM_006141.2
UniGeneiHs.369068

3D structure databases

ProteinModelPortaliA0A024R6Z0
SMRiA0A024R6Z0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R6Z0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1783
KEGGihsa:1783

Organism-specific databases

CTDi1783
EuPathDBiHostDB:ENSG00000135720.12

Phylogenomic databases

eggNOGiKOG3905 Eukaryota
ENOG410XQS4 LUCA
KOiK10416
OMAiFQDYIEP
OrthoDBiEOG091G0B3J
PhylomeDBiA0A024R6Z0

Miscellaneous databases

ChiTaRSiDYNC1LI2 human
GenomeRNAii1783

Gene expression databases

BgeeiENSG00000135720 Expressed in 246 organ(s), highest expression level in brain
ExpressionAtlasiA0A024R6Z0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR008467 Dynein1_light_intermed_chain
IPR022780 Dynein_light_int_chain
IPR027417 P-loop_NTPase
PANTHERiPTHR12688 PTHR12688, 1 hit
PfamiView protein in Pfam
PF05783 DLIC, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R6Z0_HUMAN
AccessioniPrimary (citable) accession number: A0A024R6Z0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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