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UniProtKB - A0A024R6H7 (A0A024R6H7_HUMAN)
Protein
Submitted name:
Chromosome 14 open reading frame 68, isoform CRA_b
Gene
C14orf68
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- transmembrane transport Source: InterPro
Keywordsi
Biological process | TransportUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Chromosome 14 open reading frame 68, isoform CRA_bImported |
Gene namesi | Name:C14orf68Imported ORF Names:hCG_25027Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000140107 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-UniRule
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000140107, Expressed in right lobe of liver and 73 other tissues |
ExpressionAtlasi | A0A024R6H7, baseline and differential |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 1 – 80 | SolcarPROSITE-ProRule annotationAdd BLAST | 80 | |
Repeati | 93 – 206 | SolcarPROSITE-ProRule annotationAdd BLAST | 114 | |
Repeati | 215 – 302 | SolcarPROSITE-ProRule annotationAdd BLAST | 88 |
Sequence similaritiesi
Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationARBA annotation
Keywords - Domaini
RepeatARBA annotation, TransmembranePROSITE-ProRule annotationARBA annotationPhylogenomic databases
HOGENOMi | CLU_015166_16_1_1 |
OMAi | HICRLRY |
OrthoDBi | 1072378at2759 |
PhylomeDBi | A0A024R6H7 |
Family and domain databases
Gene3Di | 1.50.40.10, 2 hits |
InterProi | View protein in InterPro IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
i Sequence
Sequence statusi: Complete.
A0A024R6H7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDFVAGAIGG VCGVAVGYPL DTVKVRIQTE PKYTGIWHCV RDTYHRERVW
60 70 80 90 100
GFYRGLSLPV CTVSLVSSVS FGTYRHCLAH ICRLRYGNPD AKPTKADITL
110 120 130 140 150
SGCASGLVRV FLTSPTEVAK VRLQTQTQAQ KQQRRLSASG PLAVPPMCPV
160 170 180 190 200
PPACPEPKYR GPLHCLATVA REEGLCGLYK GSSALVLRDG HSFATYFLSY
210 220 230 240 250
AVLCEWLSPA GHSRPDVPGV LVAGGCAGVL AWAVATPMDV IKSRLQADGQ
260 270 280 290 300
GQRRYRGLLH CMVTSVREEG PRVLFKGLVL NCCRAFPVNM VVFVAYEAVL
RLARGLLT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471061 Genomic DNA Translation: EAW81698.1 |
RefSeqi | NP_997000.2, NM_207117.2 |
Genome annotation databases
GeneIDi | 283600 |
KEGGi | hsa:283600 |
MANE-Selecti | ENST00000361529.5; ENSP00000354886.3; NM_207117.4; NP_997000.2 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471061 Genomic DNA Translation: EAW81698.1 |
RefSeqi | NP_997000.2, NM_207117.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 27517, 92 antibodies from 23 providers |
DNASUi | 283600 |
Genome annotation databases
GeneIDi | 283600 |
KEGGi | hsa:283600 |
MANE-Selecti | ENST00000361529.5; ENSP00000354886.3; NM_207117.4; NP_997000.2 |
Organism-specific databases
CTDi | 283600 |
VEuPathDBi | HostDB:ENSG00000140107 |
Phylogenomic databases
HOGENOMi | CLU_015166_16_1_1 |
OMAi | HICRLRY |
OrthoDBi | 1072378at2759 |
PhylomeDBi | A0A024R6H7 |
Miscellaneous databases
BioGRID-ORCSi | 283600, 7 hits in 1036 CRISPR screens |
GenomeRNAii | 283600 |
Gene expression databases
Bgeei | ENSG00000140107, Expressed in right lobe of liver and 73 other tissues |
ExpressionAtlasi | A0A024R6H7, baseline and differential |
Family and domain databases
Gene3Di | 1.50.40.10, 2 hits |
InterProi | View protein in InterPro IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R6H7_HUMAN | |
Accessioni | A0A024R6H7Primary (citable) accession number: A0A024R6H7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | January 19, 2022 | |
This is version 49 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |