UniProtKB - A0A024R663 (A0A024R663_HUMAN)
Protein
Submitted name:
Kinectin 1 (Kinesin receptor), isoform CRA_a
Gene
KTN1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- kinesin binding Source: InterPro
GO - Biological processi
- microtubule-based movement Source: InterPro
- protein transport Source: InterPro
Keywordsi
Molecular function | ReceptorImported |
Names & Taxonomyi
Protein namesi | Submitted name: Kinectin 1 (Kinesin receptor), isoform CRA_aImportedSubmitted name: Kinectin 1 (Kinesin receptor), isoform CRA_bImported |
Gene namesi | Name:KTN1Imported ORF Names:hCG_22120Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000126777.17 |
Subcellular locationi
Endoplasmic reticulum
- endoplasmic reticulum Source: HPA
- integral component of endoplasmic reticulum membrane Source: InterPro
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 7 – 29 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000126777, Expressed in testis and 254 other tissues |
ExpressionAtlasi | A0A024R663, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 29 – 166 | Rib_recp_KP_regInterPro annotationAdd BLAST | 138 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 48 – 81 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 103 – 218 | DisorderedSequence analysisAdd BLAST | 116 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 341 – 368 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 405 – 432 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 441 – 496 | Sequence analysisAdd BLAST | 56 | |
Coiled coili | 564 – 591 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 602 – 643 | Sequence analysisAdd BLAST | 42 | |
Coiled coili | 651 – 674 | Sequence analysisAdd BLAST | 24 | |
Coiled coili | 686 – 720 | Sequence analysisAdd BLAST | 35 | |
Coiled coili | 730 – 753 | Sequence analysisAdd BLAST | 24 | |
Coiled coili | 758 – 785 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 796 – 851 | Sequence analysisAdd BLAST | 56 | |
Coiled coili | 862 – 920 | Sequence analysisAdd BLAST | 59 | |
Coiled coili | 928 – 955 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 963 – 983 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 1015 – 1035 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 1115 – 1163 | Sequence analysisAdd BLAST | 49 | |
Coiled coili | 1175 – 1275 | Sequence analysisAdd BLAST | 101 | |
Coiled coili | 1332 – 1352 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 63 – 81 | PolyampholyteSequence analysisAdd BLAST | 19 | |
Compositional biasi | 109 – 139 | PolyampholyteSequence analysisAdd BLAST | 31 | |
Compositional biasi | 162 – 186 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 194 – 218 | PolyampholyteSequence analysisAdd BLAST | 25 |
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
HOGENOMi | CLU_005719_0_0_1 |
OMAi | GQLMHSE |
OrthoDBi | 327650at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR024854, Kinectin IPR007794, Rib_rcpt_KP |
PANTHERi | PTHR18864, PTHR18864, 1 hit |
Pfami | View protein in Pfam PF05104, Rib_recp_KP_reg, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A024R663-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEFYESAYFI VLIPSIVITV IFLFFWLFMK ETLYDEVLAK QKREQKLIPT
60 70 80 90 100
KTDKKKAEKK KNKKKEIQNG NLHESDSESV PRDFKLSDAL AVEDDQVAPV
110 120 130 140 150
PLNVVETSSS VRERKKKEKK QKPVLEEQVI KESDASKIPG KKVEPVPVTK
160 170 180 190 200
QPTPPSEAAA SKKKPGQKKS KNGSDDQDKK VETLMVPSKR QEALPLHQET
210 220 230 240 250
KQESGSGKKK ASSKKQKTEN VFVDEPLIHA TTYIPLMDNA DSSPVVDKRE
260 270 280 290 300
VIDLLKPDQV EGIQKSGTKK LKTETDKENA EVKFKDFLLS LKTMMFSEDE
310 320 330 340 350
ALCVVDLLKE KSGVIQDALK KSSKGELTTL IHQLQEKDKL LAAVKEDAAA
360 370 380 390 400
TKDRCKQLTQ EMMTEKERSN VVITRMKDRI GTLEKEHNVF QNKIHVSYQE
410 420 430 440 450
TQQMQMKFQQ VREQMEAEIA HLKQENGILR DAVSNTTNQL ESKQSAELNK
460 470 480 490 500
LRQDYARLVN ELTEKTGKLQ QEEVQKKNAE QAATQLKVQL QEAERRWEEV
510 520 530 540 550
QSYIRKRTAE HEAAQQDLQS KFVAKENEVQ SLHSKLTDTL VSKQQLEQRL
560 570 580 590 600
MQLMESEQKR VNKEESLQMQ VQDILEQNEA LKAQIQQFHS QIAAQTSASV
610 620 630 640 650
LAEELHKVIA EKDKQIKQTE DSLASERDRL TSKEEELKDI QNMNFLLKAE
660 670 680 690 700
VQKLQALANE QAAAAHELEK MQQSVYVKDD KIRLLEEQLQ HEISNKMEEF
710 720 730 740 750
KILNDQNKAL KSEVQKLQTL VSEQPNKDVV EQMEKCIQEK DEKLKTVEEL
760 770 780 790 800
LETGLIQVAT KEEELNAIRT ENSSLTKEVQ DLKAKQNDQV SFASLVEELK
810 820 830 840 850
KVIHEKDGKI KSVEELLEAE LLKVANKEKT VQDLKQEIKA LKEEIGNVQL
860 870 880 890 900
EKAQQLSITS KVQELQNLLK GKEEQMNTMK AVLEEKEKDL ANTGKWLQDL
910 920 930 940 950
QEENESLKAH VQEVAQHNLK EASSASQFEE LEIVLKEKEN ELKRLEAMLK
960 970 980 990 1000
ERESDLSSKT QLLQDVQDEN KLFKSQIEQL KQQNYQQASS FPPHEELLKV
1010 1020 1030 1040 1050
ISEREKEISG LWNELDSLKD AVEHQRKKNN DLREKNWEAM EALASTEKML
1060 1070 1080 1090 1100
QDKVNKTSKE RQQQVEAVEL EAKEVLKKLF PKVSVPSNLS YGEWLHGFEK
1110 1120 1130 1140 1150
KAKECMAGTS GSEEVKVLEH KLKEADEMHT LLQLECEKYK SVLAETEGIL
1160 1170 1180 1190 1200
QKLQRSVEQE ENKWKVKVDE SHKTIKQMQS SFTSSEQELE RLRSENKDIE
1210 1220 1230 1240 1250
NLRREREHLE MELEKAEMER STYVTEVREL KDLLTELQKK LDDSYSEAVR
1260 1270 1280 1290 1300
QNEELNLLKA QLNETLTKLR TEQNERQKVA GDLHKAQQSL ELIQSKIVKA
1310 1320 1330 1340 1350
AGDTTVIENS DVSPETESSE KETMSVSLNQ TVTQLQQLLQ AVNQQLTKEK
EHYQVLE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471061 Genomic DNA Translation: EAW80681.1 CH471061 Genomic DNA Translation: EAW80682.1 CH471061 Genomic DNA Translation: EAW80684.1 |
RefSeqi | NP_001072989.1, NM_001079521.1 XP_006720201.1, XM_006720138.2 XP_011535053.1, XM_011536751.2 XP_016876767.1, XM_017021278.1 |
Genome annotation databases
GeneIDi | 3895 |
KEGGi | hsa:3895 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471061 Genomic DNA Translation: EAW80681.1 CH471061 Genomic DNA Translation: EAW80682.1 CH471061 Genomic DNA Translation: EAW80684.1 |
RefSeqi | NP_001072989.1, NM_001079521.1 XP_006720201.1, XM_006720138.2 XP_011535053.1, XM_011536751.2 XP_016876767.1, XM_017021278.1 |
3D structure databases
SMRi | A0A024R663 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 127, 175 antibodies |
Genome annotation databases
GeneIDi | 3895 |
KEGGi | hsa:3895 |
Organism-specific databases
CTDi | 3895 |
VEuPathDBi | HostDB:ENSG00000126777.17 |
Phylogenomic databases
HOGENOMi | CLU_005719_0_0_1 |
OMAi | GQLMHSE |
OrthoDBi | 327650at2759 |
Miscellaneous databases
BioGRID-ORCSi | 3895, 4 hits in 878 CRISPR screens |
ChiTaRSi | KTN1, human |
GenomeRNAii | 3895 |
Gene expression databases
Bgeei | ENSG00000126777, Expressed in testis and 254 other tissues |
ExpressionAtlasi | A0A024R663, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR024854, Kinectin IPR007794, Rib_rcpt_KP |
PANTHERi | PTHR18864, PTHR18864, 1 hit |
Pfami | View protein in Pfam PF05104, Rib_recp_KP_reg, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R663_HUMAN | |
Accessioni | A0A024R663Primary (citable) accession number: A0A024R663 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | February 10, 2021 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |