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Protein
Submitted name:

Guanine nucleotide binding protein (G protein), beta 5, isoform CRA_a

Gene

GNB5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide binding protein (G protein), beta 5, isoform CRA_aImported
Gene namesi
Name:GNB5Imported
ORF Names:hCG_40503Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000069966.18

Expressioni

Gene expression databases

BgeeiENSG00000069966 Expressed in 220 organ(s), highest expression level in middle temporal gyrus

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 353WD_REPEATS_REGIONInterPro annotationAdd BLAST295
Repeati59 – 91WDPROSITE-ProRule annotationAdd BLAST33
Repeati149 – 190WDPROSITE-ProRule annotationAdd BLAST42
Repeati191 – 234WDPROSITE-ProRule annotationAdd BLAST44
Repeati235 – 276WDPROSITE-ProRule annotationAdd BLAST42
Repeati288 – 320WDPROSITE-ProRule annotationAdd BLAST33
Repeati321 – 353WDPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili9 – 39Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IU55 Eukaryota
ENOG410YDDC LUCA

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19850 PTHR19850, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 5 hits
PRINTSiPR00319 GPROTEINB
PR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 3 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R5R9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATEGLHENE TLASLKSEAE SLKGKLEEER AKLHDVELHQ VAERVEALGQ
60 70 80 90 100
FVMKTRRTLK GHGNKVLCMD WCKDKRRIVS SSQDGKVIVW DSFTTNKEHA
110 120 130 140 150
VTMPCTWVMA CAYAPSGCAI ACGGLDNKCS VYPLTFDKNE NMAAKKKSVA
160 170 180 190 200
MHTNYLSACS FTNSDMQILT ASGDGTCALW DVESGQLLQS FHGHGADVLC
210 220 230 240 250
LDLAPSETGN TFVSGGCDKK AMVWDMRSGQ CVQAFETHES DINSVRYYPS
260 270 280 290 300
GDAFASGSDD ATCRLYDLRA DREVAIYSKE SIIFGASSVD FSLSGRLLFA
310 320 330 340 350
GYNDYTINVW DVLKGSRVSI LFGHENRVST LRVSPDGTAF CSGSWDHTLR

VWA
Length:353
Mass (Da):38,760
Last modified:July 9, 2014 - v1
Checksum:i982B08C9F2B9976B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471082 Genomic DNA Translation: EAW77436.1
CH471082 Genomic DNA Translation: EAW77442.1
RefSeqiNP_006569.1, NM_006578.3
UniGeneiHs.155090

Genome annotation databases

GeneIDi10681

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471082 Genomic DNA Translation: EAW77436.1
CH471082 Genomic DNA Translation: EAW77442.1
RefSeqiNP_006569.1, NM_006578.3
UniGeneiHs.155090

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10681

Organism-specific databases

CTDi10681
EuPathDBiHostDB:ENSG00000069966.18

Phylogenomic databases

eggNOGiENOG410IU55 Eukaryota
ENOG410YDDC LUCA

Miscellaneous databases

ChiTaRSiGNB5 human
GenomeRNAii10681

Gene expression databases

BgeeiENSG00000069966 Expressed in 220 organ(s), highest expression level in middle temporal gyrus

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR19850 PTHR19850, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 5 hits
PRINTSiPR00319 GPROTEINB
PR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 3 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R5R9_HUMAN
AccessioniPrimary (citable) accession number: A0A024R5R9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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