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Protein
Submitted name:

Phosphatidylinositol binding clathrin assembly protein, isoform CRA_c

Gene

PICALM

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol binding clathrin assembly protein, isoform CRA_cImported
Gene namesi
Name:PICALMImported
ORF Names:hCG_1730090Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000073921.17

Subcellular locationi

PTM / Processingi

Proteomic databases

PRIDEiA0A024R5L7

Expressioni

Gene expression databases

BgeeiENSG00000073921 Expressed in 234 organ(s), highest expression level in corpus callosum
ExpressionAtlasiA0A024R5L7 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A024R5L7
SMRiA0A024R5L7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 145ENTHInterPro annotationAdd BLAST132

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili321 – 348Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3Di1.20.58.150, 1 hit
1.25.40.90, 1 hit
InterProiView protein in InterPro
IPR011417 ANTH_dom
IPR014712 Clathrin_AP_dom2
IPR013809 ENTH
IPR008942 ENTH_VHS
IPR030412 PICALM
PANTHERiPTHR22951:SF16 PTHR22951:SF16, 2 hits
PfamiView protein in Pfam
PF07651 ANTH, 1 hit
SMARTiView protein in SMART
SM00273 ENTH, 1 hit
SUPFAMiSSF48464 SSF48464, 1 hit
PROSITEiView protein in PROSITE
PS50942 ENTH, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R5L7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN
60 70 80 90 100
EMNVNIPQLA DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR
110 120 130 140 150
NTLFNLSNFL DKSGLQGYDM STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR
160 170 180 190 200
GADGVMRTMN TEKLLKTVPI IQNQMDALLD FNVNSNELTN GVINAAFMLL
210 220 230 240 250
FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF LTRMTRISEF
260 270 280 290 300
LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT
310 320 330 340 350
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP
360 370 380 390 400
HTSLTTAASP VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT
410 420 430 440 450
FHPSVHPMST ASQVASTWGG FTPSPVAQPH PSAGLNVDFE SVFGNKSTNV
460 470 480 490 500
IVDSGGFDEL GGLLKPTVAS QNQNLPVAKL PPSKLVSDDL DSSLANLVGN
510 520 530 540 550
LGIGNGTTKN DVNWSQPGEK KLTGGSNWQP KVAPTTAWNA ATMNGMHFPQ
560 570 580 590 600
YAPPVMAYPA TTPTGMIGYG IPPQMGSVPV MTQPTLIYSQ PVMRPPNPFG
610
PVSGAQIQFM
Length:610
Mass (Da):66,393
Last modified:July 9, 2014 - v1
Checksum:i3B0D0AEB901CF85D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471076 Genomic DNA Translation: EAW75122.1
RefSeqiNP_001008660.1, NM_001008660.2
UniGeneiHs.163893

Genome annotation databases

GeneIDi8301

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471076 Genomic DNA Translation: EAW75122.1
RefSeqiNP_001008660.1, NM_001008660.2
UniGeneiHs.163893

3D structure databases

ProteinModelPortaliA0A024R5L7
SMRiA0A024R5L7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R5L7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8301

Organism-specific databases

CTDi8301
EuPathDBiHostDB:ENSG00000073921.17

Miscellaneous databases

ChiTaRSiPICALM human
GenomeRNAii8301

Gene expression databases

BgeeiENSG00000073921 Expressed in 234 organ(s), highest expression level in corpus callosum
ExpressionAtlasiA0A024R5L7 baseline and differential

Family and domain databases

Gene3Di1.20.58.150, 1 hit
1.25.40.90, 1 hit
InterProiView protein in InterPro
IPR011417 ANTH_dom
IPR014712 Clathrin_AP_dom2
IPR013809 ENTH
IPR008942 ENTH_VHS
IPR030412 PICALM
PANTHERiPTHR22951:SF16 PTHR22951:SF16, 2 hits
PfamiView protein in Pfam
PF07651 ANTH, 1 hit
SMARTiView protein in SMART
SM00273 ENTH, 1 hit
SUPFAMiSSF48464 SSF48464, 1 hit
PROSITEiView protein in PROSITE
PS50942 ENTH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R5L7_HUMAN
AccessioniPrimary (citable) accession number: A0A024R5L7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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