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Protein
Submitted name:

D4, zinc and double PHD fingers family 2, isoform CRA_a

Gene

DPF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
D4, zinc and double PHD fingers family 2, isoform CRA_aImported
Gene namesi
Name:DPF2Imported
ORF Names:hCG_23274Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000133884.9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024R582

Expressioni

Gene expression databases

BgeeiENSG00000133884 Expressed in 225 organ(s), highest expression level in oocyte
ExpressionAtlasiA0A024R582 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R582
SMRiA0A024R582
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini209 – 237C2H2-typeInterPro annotationAdd BLAST29
Domaini270 – 330PHD-typeInterPro annotationAdd BLAST61
Domaini327 – 377PHD-typeInterPro annotationAdd BLAST51

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1244 Eukaryota
ENOG410YDAG LUCA
KOiK13196
PhylomeDBiA0A024R582

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR025750 Requiem/DPF_N_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00628 PHD, 1 hit
PF14051 Requiem_N, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 2 hits
SM00355 ZnF_C2H2, 1 hit
SUPFAMiSSF57667 SSF57667, 1 hit
SSF57903 SSF57903, 2 hits
PROSITEiView protein in PROSITE
PS50016 ZF_PHD_2, 2 hits
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R582-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAVVENVVK LLGEQYYKDA MEQCHNYNAR LCAERSVRLP FLDSQTGVAQ
60 70 80 90 100
SNCYIWMEKR HRGPGLASGQ LYSYPARRWR KKRRAHPPED PRLSFPSIKP
110 120 130 140 150
DTDQTLKKEG LISQDGSSLE ALLRTDPLEK RGAPDPRVDD DSLGEFPVTN
160 170 180 190 200
SRARKRILEP DDFLDDLDDE DYEEDTPKRR GKGKSKGKGV GSARKKLDAS
210 220 230 240 250
ILEDRDKPYA CDICGKRYKN RPGLSYHYAH SHLAEEEGED KEDSQPPTPV
260 270 280 290 300
SQRSEEQKSK KGPDGLALPN NYCDFCLGDS KINKKTGQPE ELVSCSDCGR
310 320 330 340 350
SGHPSCLQFT PVMMAAVKTY RWQCIECKCC NICGTSENDD QLLFCDDCDR
360 370 380 390
GYHMYCLTPS MSEPPEGSWS CHLCLDLLKE KASIYQNQNS S
Length:391
Mass (Da):44,155
Last modified:July 9, 2014 - v1
Checksum:i1044B4D3036075FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471076 Genomic DNA Translation: EAW74376.1
RefSeqiNP_006259.1, NM_006268.4
UniGeneiHs.13495
Hs.633609

Genome annotation databases

GeneIDi5977
KEGGihsa:5977

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471076 Genomic DNA Translation: EAW74376.1
RefSeqiNP_006259.1, NM_006268.4
UniGeneiHs.13495
Hs.633609

3D structure databases

ProteinModelPortaliA0A024R582
SMRiA0A024R582
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R582

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5977
KEGGihsa:5977

Organism-specific databases

CTDi5977
EuPathDBiHostDB:ENSG00000133884.9

Phylogenomic databases

eggNOGiKOG1244 Eukaryota
ENOG410YDAG LUCA
KOiK13196
PhylomeDBiA0A024R582

Miscellaneous databases

ChiTaRSiDPF2 human
GenomeRNAii5977

Gene expression databases

BgeeiENSG00000133884 Expressed in 225 organ(s), highest expression level in oocyte
ExpressionAtlasiA0A024R582 baseline and differential

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR025750 Requiem/DPF_N_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00628 PHD, 1 hit
PF14051 Requiem_N, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 2 hits
SM00355 ZnF_C2H2, 1 hit
SUPFAMiSSF57667 SSF57667, 1 hit
SSF57903 SSF57903, 2 hits
PROSITEiView protein in PROSITE
PS50016 ZF_PHD_2, 2 hits
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R582_HUMAN
AccessioniPrimary (citable) accession number: A0A024R582
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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