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UniProtKB - A0A024R4X7 (A0A024R4X7_HUMAN)
Protein
Submitted name:
HCG1989366, isoform CRA_a
Gene
hCG_1989366
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- intracellular transport Source: InterPro
- mRNA transport Source: UniProtKB-KW
- protein transport Source: UniProtKB-KW
Keywordsi
Biological process | mRNA transport, Protein transport, Translocation, Transport |
Names & Taxonomyi
Protein namesi | Submitted name: HCG1989366, isoform CRA_aImported |
Gene namesi | ORF Names:hCG_1989366Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000093000 |
Subcellular locationi
Nucleus
- nuclear pore complex ARBA annotation
Nucleus
- nuclear membrane Source: HPA
- nuclear pore Source: UniProtKB-SubCell
- nucleoplasm Source: HPA
Keywords - Cellular componenti
Nuclear pore complexARBA annotation, NucleusExpressioni
Gene expression databases
Bgeei | ENSG00000093000, Expressed in testis and 244 other tissues |
ExpressionAtlasi | A0A024R4X7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 348 – 468 | RanBD1InterPro annotationAdd BLAST | 121 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 26 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 122 – 148 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 201 – 224 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 238 – 269 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 304 – 345 | DisorderedSequence analysisAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 15 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 242 – 257 | Basic and acidic residuesSequence analysisAdd BLAST | 16 |
Phylogenomic databases
HOGENOMi | CLU_032593_0_0_1 |
OMAi | DTNPLCD |
OrthoDBi | 793797at2759 |
PhylomeDBi | A0A024R4X7 |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR015007, NUP2/50/61 IPR011993, PH-like_dom_sf IPR000156, Ran_bind_dom IPR045255, RanBP1-like |
PANTHERi | PTHR23138, PTHR23138, 1 hit |
Pfami | View protein in Pfam PF08911, NUP50, 1 hit PF00638, Ran_BP1, 1 hit |
SMARTi | View protein in SMART SM00160, RanBD, 1 hit |
PROSITEi | View protein in PROSITE PS50196, RANBD1, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A024R4X7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKRNAEKEL TDRNWDQEDE AEEVGTFSMA SEEVLKNRAI KKAKRRNVGF
60 70 80 90 100
ESDTGGAFKG FKGLVVPSGG GRFSGFGSGA GGKPLEGLSN GNNITSAPPF
110 120 130 140 150
ASAKAAADPK VAFGSLAANG PTTLVDKVSN PKTNGDSQQP SSSGLASSKA
160 170 180 190 200
CVGNAYHKQL AALNCSVRDW IVKHVNTNPL CDLTPIFKDY EKYLANIEQQ
210 220 230 240 250
HGNSGRNSES ESNKVAAETQ SPSLFGSTKL QQESTFLFHG NKTEDTPDKK
260 270 280 290 300
MEVASEKKTD PSSLGATSAS FNFGKKVDSS VLGSLSSVPL TGFSFSPGNS
310 320 330 340 350
SLFGKDTTQS KPVSSPFPTK PLEGQAEGDS GECKGGDEEE NDEPPKVVVT
360 370 380 390 400
EVKEEDAFYS KKCKLFYKKD NEFKEKGIGT LHLKPTANQK TQLLVRADTN
410 420 430 440 450
LGNILLNVLI PPNMPCTRTG KNNVLIVCVP NPPIDEKNAT MPVTMLIRVK
460
TSEDADELHK ILLEKKDA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471138 Genomic DNA Translation: EAW73373.1 |
RefSeqi | NP_009103.2, NM_007172.3 XP_006724166.1, XM_006724103.1 XP_011528135.1, XM_011529833.1 |
Genome annotation databases
GeneIDi | 10762 |
KEGGi | hsa:10762 |
MANE-Selecti | ENST00000347635.9; ENSP00000345895.3; NM_007172.4; NP_009103.2 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471138 Genomic DNA Translation: EAW73373.1 |
RefSeqi | NP_009103.2, NM_007172.3 XP_006724166.1, XM_006724103.1 XP_011528135.1, XM_011529833.1 |
3D structure databases
SMRi | A0A024R4X7 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 27795, 362 antibodies from 33 providers |
DNASUi | 10762 |
Genome annotation databases
GeneIDi | 10762 |
KEGGi | hsa:10762 |
MANE-Selecti | ENST00000347635.9; ENSP00000345895.3; NM_007172.4; NP_009103.2 |
Organism-specific databases
CTDi | 10762 |
VEuPathDBi | HostDB:ENSG00000093000 |
Phylogenomic databases
HOGENOMi | CLU_032593_0_0_1 |
OMAi | DTNPLCD |
OrthoDBi | 793797at2759 |
PhylomeDBi | A0A024R4X7 |
Miscellaneous databases
BioGRID-ORCSi | 10762, 293 hits in 1052 CRISPR screens |
GenomeRNAii | 10762 |
Gene expression databases
Bgeei | ENSG00000093000, Expressed in testis and 244 other tissues |
ExpressionAtlasi | A0A024R4X7, baseline and differential |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR015007, NUP2/50/61 IPR011993, PH-like_dom_sf IPR000156, Ran_bind_dom IPR045255, RanBP1-like |
PANTHERi | PTHR23138, PTHR23138, 1 hit |
Pfami | View protein in Pfam PF08911, NUP50, 1 hit PF00638, Ran_BP1, 1 hit |
SMARTi | View protein in SMART SM00160, RanBD, 1 hit |
PROSITEi | View protein in PROSITE PS50196, RANBD1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R4X7_HUMAN | |
Accessioni | A0A024R4X7Primary (citable) accession number: A0A024R4X7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | May 25, 2022 | |
This is version 45 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |