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Protein
Submitted name:

HCG2008146, isoform CRA_c

Gene

hCG_2008146

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
HCG2008146, isoform CRA_cImported
Gene namesi
ORF Names:hCG_2008146Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000256087.6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000256087 Expressed in 219 organ(s), highest expression level in endothelial cell

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 79KRABInterPro annotationAdd BLAST72
Domaini205 – 232C2H2-typeInterPro annotationAdd BLAST28
Domaini233 – 260C2H2-typeInterPro annotationAdd BLAST28
Domaini261 – 288C2H2-typeInterPro annotationAdd BLAST28
Domaini289 – 316C2H2-typeInterPro annotationAdd BLAST28
Domaini317 – 344C2H2-typeInterPro annotationAdd BLAST28
Domaini345 – 372C2H2-typeInterPro annotationAdd BLAST28
Domaini373 – 400C2H2-typeInterPro annotationAdd BLAST28
Domaini401 – 428C2H2-typeInterPro annotationAdd BLAST28
Domaini429 – 456C2H2-typeInterPro annotationAdd BLAST28
Domaini457 – 484C2H2-typeInterPro annotationAdd BLAST28
Domaini485 – 512C2H2-typeInterPro annotationAdd BLAST28
Domaini513 – 540C2H2-typeInterPro annotationAdd BLAST28
Domaini541 – 568C2H2-typeInterPro annotationAdd BLAST28
Domaini569 – 596C2H2-typeInterPro annotationAdd BLAST28
Domaini597 – 624C2H2-typeInterPro annotationAdd BLAST28
Domaini625 – 652C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
KOiK09228
OMAiFTVKSML
OrthoDBiEOG091G02KC

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 15 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 16 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 9 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 16 hits
PS50157 ZINC_FINGER_C2H2_2, 16 hits

Sequencei

Sequence statusi: Complete.

A0A024R4I3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MINAQELLTL EDVTVEFTWE EWQLLGPFQK DLYRDVMLEI YSNLLSMGYQ
60 70 80 90 100
VSKPDALSKL ERGEEPWTME DERHSRICPE NNEVDDHLQD HLENQRMLKS
110 120 130 140 150
VEQYHEHNAF GNTASQTKSL CLFRENHDTF ELYIKTLKSN LSLVNQNKSC
160 170 180 190 200
EINNSTKFSG DGKSFLHGNY EELYSAAKFS VSTKANSTKS QVSKHQRTHE
210 220 230 240 250
IEKNHVCSEC GKAFVKKSQL TDHERVHTGE KPYGCTLCAK VFSRKSRLNE
260 270 280 290 300
HQRIHKREKS FICSECGKVF TMKSRLIEHQ RTHTGEKPYI CNECGKGFPG
310 320 330 340 350
KRNLIVHQRN HTGEKSYICS ECGKGFTGKS MLIIHQRTHT GEKPYICSEC
360 370 380 390 400
GKGFTTKHYV IIHQRNHTGE KPYICNECGK GFTMKSRMIE HQRTHTGEKP
410 420 430 440 450
YICSECGKGF PRKSNLIVHQ RNHTVEKSYL CSECGKGFTV KSMLIIHQRT
460 470 480 490 500
HTGEKPYTCS ECGKGFPLKS RLIVHQRTHT GEKPYRCSEC GKGFIVNSGL
510 520 530 540 550
MLHQRTHTGE KPYICNECGK GFAFKSNLVV HQRTHTGEKP FMCSECGKGF
560 570 580 590 600
TMKRYLIVHQ QIHTEEKSCI CSECGRGFAK ETELALHKQV HTGEKPYGCN
610 620 630 640 650
ECGKGFTMKS RLIVHQRTHT GEKPFVCSEC RKAFSSKRNL IVHQRTHNGN

KP
Length:652
Mass (Da):74,836
Last modified:July 9, 2014 - v1
Checksum:i14B61461EE54A6EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471135 Genomic DNA Translation: EAW72060.1
CH471135 Genomic DNA Translation: EAW72062.1
RefSeqiNP_001309213.1, NM_001322284.1
NP_001309214.1, NM_001322285.1
NP_055465.1, NM_014650.3
UniGeneiHs.655934
Hs.665751

Genome annotation databases

GeneIDi9668
KEGGihsa:9668

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471135 Genomic DNA Translation: EAW72060.1
CH471135 Genomic DNA Translation: EAW72062.1
RefSeqiNP_001309213.1, NM_001322284.1
NP_001309214.1, NM_001322285.1
NP_055465.1, NM_014650.3
UniGeneiHs.655934
Hs.665751

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9668
KEGGihsa:9668

Organism-specific databases

CTDi9668
EuPathDBiHostDB:ENSG00000256087.6

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
KOiK09228
OMAiFTVKSML
OrthoDBiEOG091G02KC

Miscellaneous databases

GenomeRNAii9668

Gene expression databases

BgeeiENSG00000256087 Expressed in 219 organ(s), highest expression level in endothelial cell

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 15 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 16 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 9 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 16 hits
PS50157 ZINC_FINGER_C2H2_2, 16 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R4I3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R4I3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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