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Protein
Submitted name:

ATG16 autophagy related 16-like 1 (S. cerevisiae), isoform CRA_b

Gene

ATG16L1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
ATG16 autophagy related 16-like 1 (S. cerevisiae), isoform CRA_bImported
Gene namesi
Name:ATG16L1Imported
ORF Names:hCG_1817841Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000085978.21

PTM / Processingi

Proteomic databases

PRIDEiA0A024R494

Expressioni

Gene expression databases

BgeeiENSG00000085978 Expressed in 193 organ(s), highest expression level in frontal cortex
ExpressionAtlasiA0A024R494 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R494
SMRiA0A024R494
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini299 – 588WD_REPEATS_REGIONInterPro annotationAdd BLAST290
Repeati299 – 332WDPROSITE-ProRule annotationAdd BLAST34
Repeati343 – 384WDPROSITE-ProRule annotationAdd BLAST42
Repeati385 – 426WDPROSITE-ProRule annotationAdd BLAST42
Repeati443 – 465WDPROSITE-ProRule annotationAdd BLAST23
Repeati521 – 552WDPROSITE-ProRule annotationAdd BLAST32
Repeati554 – 588WDPROSITE-ProRule annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili78 – 102Sequence analysisAdd BLAST25
Coiled coili110 – 144Sequence analysisAdd BLAST35
Coiled coili159 – 179Sequence analysisAdd BLAST21
Coiled coili195 – 230Sequence analysisAdd BLAST36

Keywords - Domaini

Coiled coilSequence analysis, WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0288 Eukaryota
ENOG410XQYA LUCA

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR013923 Autophagy-rel_prot_16
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF08614 ATG16, 1 hit
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 3 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R494-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSGLRAADF PRWKRHISEQ LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS
60 70 80 90 100
VLAQKLQAEK HDVPNRHEIS PGHDGTWNDN QLQEMAQLRI KHQEELTELH
110 120 130 140 150
KKRGELAQLV IDLNNQMQRK DREMQMNEAK IAECLQTISD LETECLDLRT
160 170 180 190 200
KLCDLERANQ TLKDEYDALQ ITFTALEGKL RKTTEENQEL VTRWMAEKAQ
210 220 230 240 250
EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI EVIVDETSDH
260 270 280 290 300
TEETSPVRAI SRAATRRSVS SFPVPQDNVD THPGSGKEVR VPATALCVFD
310 320 330 340 350
AHDGEVNAVQ FSPGSRLLAT GGMDRRVKLW EVFGEKCEFK GSLSGSNAGI
360 370 380 390 400
TSIEFDSAGS YLLAASNDFA SRIWTVDDYR LRHTLTGHSG KVLSAKFLLD
410 420 430 440 450
NARIVSGSHD RTLKLWDLRS KVCIKTVFAG SSCNDIVCTE QCVMSGHFDK
460 470 480 490 500
KIRFWDIRSE SIVREMELLG KITALDLNPE RTELLSCSRD DLLKVIDLRT
510 520 530 540 550
NAIKQTFSAP GFKCGSDWTR VVFSPDGSYV AAGSAEGSLY IWSVLTGKVE
560 570 580
KVLSKQHSSS INAVAWSPSG SHVVSVDKGC KAVLWAQY
Length:588
Mass (Da):66,296
Last modified:July 9, 2014 - v1
Checksum:i168A0E53B2190149
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471063 Genomic DNA Translation: EAW71040.1
RefSeqiNP_060444.3, NM_017974.3
UniGeneiHs.529322

Genome annotation databases

GeneIDi55054

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471063 Genomic DNA Translation: EAW71040.1
RefSeqiNP_060444.3, NM_017974.3
UniGeneiHs.529322

3D structure databases

ProteinModelPortaliA0A024R494
SMRiA0A024R494
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R494

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi55054

Organism-specific databases

CTDi55054
EuPathDBiHostDB:ENSG00000085978.21

Phylogenomic databases

eggNOGiKOG0288 Eukaryota
ENOG410XQYA LUCA

Miscellaneous databases

GenomeRNAii55054

Gene expression databases

BgeeiENSG00000085978 Expressed in 193 organ(s), highest expression level in frontal cortex
ExpressionAtlasiA0A024R494 baseline and differential

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR013923 Autophagy-rel_prot_16
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF08614 ATG16, 1 hit
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 3 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R494_HUMAN
AccessioniPrimary (citable) accession number: A0A024R494
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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