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Protein
Submitted name:

Friend leukemia virus integration 1, isoform CRA_a

Gene

FLI1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Friend leukemia virus integration 1, isoform CRA_aImported
Gene namesi
Name:FLI1Imported
ORF Names:hCG_39646Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000151702.16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiA0A024R3M5

Expressioni

Gene expression databases

BgeeiENSG00000151702 Expressed in 188 organ(s), highest expression level in leukocyte
ExpressionAtlasiA0A024R3M5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R3M5
SMRiA0A024R3M5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 198PNTInterPro annotationAdd BLAST87
Domaini281 – 361ETSInterPro annotationAdd BLAST81

Sequence similaritiesi

Belongs to the ETS family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3806 Eukaryota
ENOG410Z0ZF LUCA
KOiK09436
OMAiNPDYGQP
OrthoDBiEOG091G0EWP
PhylomeDBiA0A024R3M5

Family and domain databases

CDDicd08541 SAM_PNT-FLI-1, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000418 Ets_dom
IPR035575 Fli-1
IPR003118 Pointed_dom
IPR013761 SAM/pointed_sf
IPR035573 SAM_PNT-FLI-1
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR11849:SF161 PTHR11849:SF161, 1 hit
PfamiView protein in Pfam
PF00178 Ets, 1 hit
PF02198 SAM_PNT, 1 hit
PRINTSiPR00454 ETSDOMAIN
SMARTiView protein in SMART
SM00413 ETS, 1 hit
SM00251 SAM_PNT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS00345 ETS_DOMAIN_1, 1 hit
PS00346 ETS_DOMAIN_2, 1 hit
PS50061 ETS_DOMAIN_3, 1 hit
PS51433 PNT, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R3M5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGTIKEALS VVSDDQSLFD SAYGAAAHLP KADMTASGSP DYGQPHKINP
60 70 80 90 100
LPPQQEWINQ PVRVNVKREY DHMNGSRESP VDCSVSKCSK LVGGGESNPM
110 120 130 140 150
NYNSYMDEKN GPPPPNMTTN ERRVIVPADP TLWTQEHVRQ WLEWAIKEYS
160 170 180 190 200
LMEIDTSFFQ NMDGKELCKM NKEDFLRATT LYNTEVLLSH LSYLRESSLL
210 220 230 240 250
AYNTTSHTDQ SSRLSVKEDP SYDSVRRGAW GNNMNSGLNK SPPLGGAQTI
260 270 280 290 300
SKNTEQRPQP DPYQILGPTS SRLANPGSGQ IQLWQFLLEL LSDSANASCI
310 320 330 340 350
TWEGTNGEFK MTDPDEVARR WGERKSKPNM NYDKLSRALR YYYDKNIMTK
360 370 380 390 400
VHGKRYAYKF DFHGIAQALQ PHPTESSMYK YPSDISYMPS YHAHQQKVNF
410 420 430 440 450
VPPHPSSMPV TSSSFFGAAS QYWTSPTGGI YPNPNVPRHP NTHVPSHLGS

YY
Length:452
Mass (Da):50,982
Last modified:July 9, 2014 - v1
Checksum:i9C2AAEEAF683F3FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471065 Genomic DNA Translation: EAW67720.1
RefSeqiNP_002008.2, NM_002017.4
UniGeneiHs.504281

Genome annotation databases

GeneIDi2313
KEGGihsa:2313

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471065 Genomic DNA Translation: EAW67720.1
RefSeqiNP_002008.2, NM_002017.4
UniGeneiHs.504281

3D structure databases

ProteinModelPortaliA0A024R3M5
SMRiA0A024R3M5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R3M5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2313
KEGGihsa:2313

Organism-specific databases

CTDi2313
EuPathDBiHostDB:ENSG00000151702.16

Phylogenomic databases

eggNOGiKOG3806 Eukaryota
ENOG410Z0ZF LUCA
KOiK09436
OMAiNPDYGQP
OrthoDBiEOG091G0EWP
PhylomeDBiA0A024R3M5

Miscellaneous databases

ChiTaRSiFLI1 human
GenomeRNAii2313

Gene expression databases

BgeeiENSG00000151702 Expressed in 188 organ(s), highest expression level in leukocyte
ExpressionAtlasiA0A024R3M5 baseline and differential

Family and domain databases

CDDicd08541 SAM_PNT-FLI-1, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000418 Ets_dom
IPR035575 Fli-1
IPR003118 Pointed_dom
IPR013761 SAM/pointed_sf
IPR035573 SAM_PNT-FLI-1
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR11849:SF161 PTHR11849:SF161, 1 hit
PfamiView protein in Pfam
PF00178 Ets, 1 hit
PF02198 SAM_PNT, 1 hit
PRINTSiPR00454 ETSDOMAIN
SMARTiView protein in SMART
SM00413 ETS, 1 hit
SM00251 SAM_PNT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS00345 ETS_DOMAIN_1, 1 hit
PS00346 ETS_DOMAIN_2, 1 hit
PS50061 ETS_DOMAIN_3, 1 hit
PS51433 PNT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R3M5_HUMAN
AccessioniPrimary (citable) accession number: A0A024R3M5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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