Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a

Gene

CTNNB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_aImported
Gene namesi
Name:CTNNB1Imported
ORF Names:hCG_27815Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000168036.16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000168036 Expressed in 240 organ(s), highest expression level in adrenal tissue

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati151 – 191ARMPROSITE-ProRule annotationAdd BLAST41
Repeati193 – 236ARMPROSITE-ProRule annotationAdd BLAST44
Repeati235 – 277ARMPROSITE-ProRule annotationAdd BLAST43
Repeati277 – 319ARMPROSITE-ProRule annotationAdd BLAST43
Repeati319 – 362ARMPROSITE-ProRule annotationAdd BLAST44
Repeati400 – 442ARMPROSITE-ProRule annotationAdd BLAST43
Repeati442 – 484ARMPROSITE-ProRule annotationAdd BLAST43
Repeati489 – 532ARMPROSITE-ProRule annotationAdd BLAST44
Repeati594 – 636ARMPROSITE-ProRule annotationAdd BLAST43

Phylogenomic databases

eggNOGiKOG4203 Eukaryota
COG0035 LUCA
KOiK02105
OMAiFNQNFSQ
OrthoDBiEOG091G03A5

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR013284 Beta-catenin
PfamiView protein in Pfam
PF00514 Arm, 4 hits
PRINTSiPR01869 BCATNINFAMLY
SMARTiView protein in SMART
SM00185 ARM, 12 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 9 hits

Sequencei

Sequence statusi: Complete.

A0A024R2Q3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATQADLMEL DMAMEPDRKA AVSHWQQQSY LDSGIHSGAT TTAPSLSGKG
60 70 80 90 100
NPEEEDVDTS QVLYEWEQGF SQSFTQEQVA DIDGQYAMTR AQRVRAAMFP
110 120 130 140 150
ETLDEGMQIP STQFDAAHPT NVQRLAEPSQ MLKHAVVNLI NYQDDAELAT
160 170 180 190 200
RAIPELTKLL NDEDQVVVNK AAVMVHQLSK KEASRHAIMR SPQMVSAIVR
210 220 230 240 250
TMQNTNDVET ARCTAGTLHN LSHHREGLLA IFKSGGIPAL VKMLGSPVDS
260 270 280 290 300
VLFYAITTLH NLLLHQEGAK MAVRLAGGLQ KMVALLNKTN VKFLAITTDC
310 320 330 340 350
LQILAYGNQE SKLIILASGG PQALVNIMRT YTYEKLLWTT SRVLKVLSVC
360 370 380 390 400
SSNKPAIVEA GGMQALGLHL TDPSQRLVQN CLWTLRNLSD AATKQEGMEG
410 420 430 440 450
LLGTLVQLLG SDDINVVTCA AGILSNLTCN NYKNKMMVCQ VGGIEALVRT
460 470 480 490 500
VLRAGDREDI TEPAICALRH LTSRHQEAEM AQNAVRLHYG LPVVVKLLHP
510 520 530 540 550
PSHWPLIKAT VGLIRNLALC PANHAPLREQ GAIPRLVQLL VRAHQDTQRR
560 570 580 590 600
TSMGGTQQQF VEGVRMEEIV EGCTGALHIL ARDVHNRIVI RGLNTIPLFV
610 620 630 640 650
QLLYSPIENI QRVAAGVLCE LAQDKEAAEA IEAEGATAPL TELLHSRNEG
660 670 680 690 700
VATYAAAVLF RMSEDKPQDY KKRLSVELTS SLFRTEPMAW NETADLGLDI
710 720 730 740 750
GAQGEPLGYR QDDPSYRSFH SGGYGQDALG MDPMMEHEMG GHHPGADYPV
760 770 780
DGLPDLGHAQ DLMDGLPPGD SNQLAWFDTD L
Length:781
Mass (Da):85,497
Last modified:July 9, 2014 - v1
Checksum:iCB78F165A3EEF86E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471055 Genomic DNA Translation: EAW64626.1
CH471055 Genomic DNA Translation: EAW64627.1
CH471055 Genomic DNA Translation: EAW64628.1
RefSeqiNP_001091679.1, NM_001098209.1
NP_001091680.1, NM_001098210.1
NP_001895.1, NM_001904.3
XP_005264943.1, XM_005264886.2
XP_016861227.1, XM_017005738.1
UniGeneiHs.476018
Hs.712929

Genome annotation databases

GeneIDi1499
KEGGihsa:1499

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471055 Genomic DNA Translation: EAW64626.1
CH471055 Genomic DNA Translation: EAW64627.1
CH471055 Genomic DNA Translation: EAW64628.1
RefSeqiNP_001091679.1, NM_001098209.1
NP_001091680.1, NM_001098210.1
NP_001895.1, NM_001904.3
XP_005264943.1, XM_005264886.2
XP_016861227.1, XM_017005738.1
UniGeneiHs.476018
Hs.712929

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1499
KEGGihsa:1499

Organism-specific databases

CTDi1499
EuPathDBiHostDB:ENSG00000168036.16

Phylogenomic databases

eggNOGiKOG4203 Eukaryota
COG0035 LUCA
KOiK02105
OMAiFNQNFSQ
OrthoDBiEOG091G03A5

Miscellaneous databases

ChiTaRSiCTNNB1 human
GenomeRNAii1499

Gene expression databases

BgeeiENSG00000168036 Expressed in 240 organ(s), highest expression level in adrenal tissue

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR013284 Beta-catenin
PfamiView protein in Pfam
PF00514 Arm, 4 hits
PRINTSiPR01869 BCATNINFAMLY
SMARTiView protein in SMART
SM00185 ARM, 12 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 9 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R2Q3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R2Q3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again