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Protein
Submitted name:

Ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast), isoform CRA_a

Gene

UBE2E1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei131Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseSAAS annotation
Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast), isoform CRA_aImported
Gene namesi
Name:UBE2E1Imported
ORF Names:hCG_14891Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000170142.11

PTM / Processingi

Proteomic databases

PRIDEiA0A024R2K3

Expressioni

Gene expression databases

BgeeiENSG00000170142 Expressed in 236 organ(s), highest expression level in embryo
ExpressionAtlasiA0A024R2K3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R2K3
SMRiA0A024R2K3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 182UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0417 Eukaryota
COG5078 LUCA
KOiK20217
OrthoDBiEOG091G0GF8
PhylomeDBiA0A024R2K3

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R2K3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDDDSRAST SSSSSSSSNQ QTEKETNTPK KKESKVSMSK NSKLLSTSAK
60 70 80 90 100
RIQKELADIT LDPPPNCSAG PKGDNIYEWR STILGPPGSV YEGGVFFLDI
110 120 130 140 150
TFTPEYPFKP PKVTFRTRIY HCNINSQGVI CLDILKDNWS PALTISKVLL
160 170 180 190
SICSLLTDCN PADPLVGSIA TQYMTNRAEH DRMARQWTKR YAT
Length:193
Mass (Da):21,404
Last modified:July 9, 2014 - v1
Checksum:i2FBC50BE2A6A0008
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471055 Genomic DNA Translation: EAW64333.1
RefSeqiNP_003332.1, NM_003341.4
UniGeneiHs.164853

Genome annotation databases

GeneIDi7324
KEGGihsa:7324

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471055 Genomic DNA Translation: EAW64333.1
RefSeqiNP_003332.1, NM_003341.4
UniGeneiHs.164853

3D structure databases

ProteinModelPortaliA0A024R2K3
SMRiA0A024R2K3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R2K3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7324
KEGGihsa:7324

Organism-specific databases

CTDi7324
EuPathDBiHostDB:ENSG00000170142.11

Phylogenomic databases

eggNOGiKOG0417 Eukaryota
COG5078 LUCA
KOiK20217
OrthoDBiEOG091G0GF8
PhylomeDBiA0A024R2K3

Miscellaneous databases

ChiTaRSiUBE2E1 human
GenomeRNAii7324

Gene expression databases

BgeeiENSG00000170142 Expressed in 236 organ(s), highest expression level in embryo
ExpressionAtlasiA0A024R2K3 baseline and differential

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R2K3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R2K3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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