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Protein
Submitted name:

Vesicle amine transport protein 1 homolog (T californica), isoform CRA_a

Gene

VAT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Vesicle amine transport protein 1 homolog (T californica), isoform CRA_aImported
Gene namesi
Name:VAT1Imported
ORF Names:hCG_16957Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000108828.15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024R1Z6

Expressioni

Gene expression databases

BgeeiENSG00000108828 Expressed in 237 organ(s), highest expression level in right adrenal gland cortex
ExpressionAtlasiA0A024R1Z6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R1Z6
SMRiA0A024R1Z6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 385PKS_ERInterPro annotationAdd BLAST329

Phylogenomic databases

eggNOGiKOG1198 Eukaryota
COG0604 LUCA
OMAiTLRVRAC
OrthoDBiEOG091G0EEJ
PhylomeDBiA0A024R1Z6

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
IPR020843 PKS_ER
IPR002364 Quin_OxRdtase/zeta-crystal_CS
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SMARTiView protein in SMART
SM00829 PKS_ER, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS01162 QOR_ZETA_CRYSTAL, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R1Z6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDEREVAEA ATGEDASSPP PKTEAASDPQ HPAASEGAAA AAASPPLLRC
60 70 80 90 100
LVLTGFGGYD KVKLQSRPAA PPAPGPGQLT LRLRACGLNF ADLMARQGLY
110 120 130 140 150
DRLPPLPVTP GMEGAGVVIA VGEGVSDRKA GDRVMVLNRS GMWQEEVTVP
160 170 180 190 200
SVQTFLIPEA MTFEEAAALL VNYITAYMVL FDFGNLQPGH SVLVHMAAGG
210 220 230 240 250
VGMAAVQLCR TVENVTVFGT ASASKHEALK ENGVTHPIDY HTTDYVDEIK
260 270 280 290 300
KISPKGVDIV MDPLGGSDTA KGYNLLKPMG KVVTYGMANL LTGPKRNLMA
310 320 330 340 350
LARTWWNQFS VTALQLLQAN RAVCGFHLGY LDGEVELVSG VVARLLALYN
360 370 380 390
QGHIKPHIDS VWPFEKVADA MKQMQEKKNV GKVLLVPGPE KEN
Length:393
Mass (Da):41,920
Last modified:July 9, 2014 - v1
Checksum:i25933347742C2FE6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471152 Genomic DNA Translation: EAW60918.1
RefSeqiNP_006364.2, NM_006373.3
UniGeneiHs.514199

Genome annotation databases

GeneIDi10493
KEGGihsa:10493

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471152 Genomic DNA Translation: EAW60918.1
RefSeqiNP_006364.2, NM_006373.3
UniGeneiHs.514199

3D structure databases

ProteinModelPortaliA0A024R1Z6
SMRiA0A024R1Z6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A024R1Z6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10493
KEGGihsa:10493

Organism-specific databases

CTDi10493
EuPathDBiHostDB:ENSG00000108828.15

Phylogenomic databases

eggNOGiKOG1198 Eukaryota
COG0604 LUCA
OMAiTLRVRAC
OrthoDBiEOG091G0EEJ
PhylomeDBiA0A024R1Z6

Miscellaneous databases

ChiTaRSiVAT1 human
GenomeRNAii10493

Gene expression databases

BgeeiENSG00000108828 Expressed in 237 organ(s), highest expression level in right adrenal gland cortex
ExpressionAtlasiA0A024R1Z6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
IPR020843 PKS_ER
IPR002364 Quin_OxRdtase/zeta-crystal_CS
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SMARTiView protein in SMART
SM00829 PKS_ER, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS01162 QOR_ZETA_CRYSTAL, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R1Z6_HUMAN
AccessioniPrimary (citable) accession number: A0A024R1Z6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 12, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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