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Protein
Submitted name:

Excision repair cross-complementing rodent repair deficiency, complementation group 1 (Includes overlapping antisense sequence), isoform CRA_a

Gene

ERCC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Excision repair cross-complementing rodent repair deficiency, complementation group 1 (Includes overlapping antisense sequence), isoform CRA_aImported
Gene namesi
Name:ERCC1Imported
ORF Names:hCG_20728Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000012061.15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000012061
ExpressionAtlasiA0A024R0Q6 baseline and differential

Structurei

3D structure databases

SMRiA0A024R0Q6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2841 Eukaryota
COG5241 LUCA
KOiK10849

Family and domain databases

InterProiView protein in InterPro
IPR004579 ERCC1/RAD10/SWI10
IPR011335 Restrct_endonuc-II-like
IPR010994 RuvA_2-like
PANTHERiPTHR12749 PTHR12749, 1 hit
PfamiView protein in Pfam
PF03834 Rad10, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD013585 DNA_repair_Rad10, 1 hit
SUPFAMiSSF47781 SSF47781, 1 hit
SSF52980 SSF52980, 1 hit
TIGRFAMsiTIGR00597 rad10, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R0Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPGKDKEGV PQPSGPPARK KFVIPLDEDE VPPGVAKPLF RSTQSLPTVD
60 70 80 90 100
TSAQAAPQTY AEYAISQPLE GAGATCPTGS EPLAGETPNQ ALKPGAKSNS
110 120 130 140 150
IIVSPRQRGN PVLKFVRNVP WEFGDVIPDY VLGQSTCALF LSLRYHNLHP
160 170 180 190 200
DYIHGRLQSL GKNFALRVLL VQVDVKDPQQ ALKELAKMCI LADCTLILAW
210 220 230 240 250
SPEEAGRYLE TYKAYEQKPA DLLMEKLEQD FVSRVTECLT TVKSVNKTDS
260 270 280 290
QTLLTTFGSL EQLIAASRED LALCPGLGPQ KARRLFDVLH EPFLKVP
Length:297
Mass (Da):32,562
Last modified:July 9, 2014 - v1
Checksum:i6FCE3615732349E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471126 Genomic DNA Translation: EAW57348.1
CH471126 Genomic DNA Translation: EAW57350.1
RefSeqiNP_001974.1, NM_001983.3
XP_016881949.1, XM_017026460.1
XP_016881950.1, XM_017026461.1
XP_016881951.1, XM_017026462.1
XP_016881952.1, XM_017026463.1
XP_016881953.1, XM_017026464.1
UniGeneiHs.435981

Genome annotation databases

GeneIDi2067
KEGGihsa:2067

Similar proteinsi

Entry informationi

Entry nameiA0A024R0Q6_HUMAN
AccessioniPrimary (citable) accession number: A0A024R0Q6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: May 23, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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