UniProtKB - A0A024R0N8 (A0A024R0N8_HUMAN)
Protein
Kinase
Gene
ITPKC
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- inositol-1,4,5-trisphosphate 3-kinase activity Source: Ensembl
GO - Biological processi
- inositol phosphate biosynthetic process Source: InterPro
Keywordsi
Molecular function | KinaseUniRule annotationImported, Transferase |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ITPKCImported ORF Names:hCG_20795Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000086544.2 |
Expressioni
Gene expression databases
Bgeei | ENSG00000086544, Expressed in lower esophagus mucosa and 209 other tissues |
ExpressionAtlasi | A0A024R0N8, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 124 | DisorderedSequence analysisAdd BLAST | 124 | |
Regioni | 147 – 308 | DisorderedSequence analysisAdd BLAST | 162 | |
Regioni | 334 – 387 | DisorderedSequence analysisAdd BLAST | 54 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 107 – 123 | PolyampholyteSequence analysisAdd BLAST | 17 | |
Compositional biasi | 176 – 209 | PolarSequence analysisAdd BLAST | 34 | |
Compositional biasi | 264 – 289 | PolarSequence analysisAdd BLAST | 26 |
Sequence similaritiesi
Phylogenomic databases
HOGENOMi | CLU_017767_5_0_1 |
OMAi | ADNLWTH |
OrthoDBi | 966687at2759 |
Family and domain databases
Gene3Di | 1.10.510.50, 1 hit |
InterProi | View protein in InterPro IPR005522, IPK IPR038286, IPK_sf |
PANTHERi | PTHR12400, PTHR12400, 1 hit |
Pfami | View protein in Pfam PF03770, IPK, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A024R0N8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRRCPCRGSL NEAEAGALPA AARMGLEAPR GGRRRQPGQQ RPGPGAGAPA
60 70 80 90 100
GRPEGGGPWA RTEGSSLHSE PERAGLGPAP GTESPQAEFW TDGQTEPAAA
110 120 130 140 150
GLGVETERPK QKTEPDRSSL RTHLEWSWSE LETTCLWTET GTDGLWTDPH
160 170 180 190 200
RSDLQFQPEE ASPWTQPGVH GPWTELETHG SQTQPERVKS WADNLWTHQN
210 220 230 240 250
SSSLQTHPEG ACPSKEPSAD GSWKELYTDG SRTQQDIEGP WTEPYTDGSQ
260 270 280 290 300
KKQDTEAARK QPGTGGFQIQ QDTDGSWTQP STDGSQTAPG TDCLLGEPED
310 320 330 340 350
GPLEEPEPGE LLTHLYSHLK CSPLCPVPRL IITPETPEPE AQPVGPPSRV
360 370 380 390 400
EGGSGGFSSA SSFDESEDDV VAGGGGASDP EDRSGSKPWK KLKTVLKYSP
410 420 430 440 450
FVVSFRKHYP WVQLSGHAGN FQAGEDGRIL KRFCQCEQRS LEQLMKDPLR
460 470 480 490 500
PFVPAYYGMV LQDGQTFNQM EDLLADFEGP SIMDCKMGSR TYLEEELVKA
510 520 530 540 550
RERPRPRKDM YEKMVAVDPG APTPEEHAQG AVTKPRYMQW RETMSSTSTL
560 570 580 590 600
GFRIEGIKKA DGTCNTNFKK TQALEQVTKV LEDFVDGDHV ILQKYVACLE
610 620 630 640 650
ELREALEISP FFKTHEVVGS SLLFVHDHTG LAKVWMIDFG KTVALPDHQT
660 670 680
LSHRLPWAEG NREDGYLWGL DNMICLLQGL AQS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471126 Genomic DNA Translation: EAW56992.1 CH471126 Genomic DNA Translation: EAW56993.1 |
RefSeqi | NP_079470.1, NM_025194.2 |
Genome annotation databases
GeneIDi | 80271 |
KEGGi | hsa:80271 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH471126 Genomic DNA Translation: EAW56992.1 CH471126 Genomic DNA Translation: EAW56993.1 |
RefSeqi | NP_079470.1, NM_025194.2 |
3D structure databases
SMRi | A0A024R0N8 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 30626, 183 antibodies |
DNASUi | 80271 |
Genome annotation databases
GeneIDi | 80271 |
KEGGi | hsa:80271 |
Organism-specific databases
CTDi | 80271 |
VEuPathDBi | HostDB:ENSG00000086544.2 |
Phylogenomic databases
HOGENOMi | CLU_017767_5_0_1 |
OMAi | ADNLWTH |
OrthoDBi | 966687at2759 |
Miscellaneous databases
BioGRID-ORCSi | 80271, 4 hits in 998 CRISPR screens |
ChiTaRSi | ITPKC, human |
GenomeRNAii | 80271 |
Gene expression databases
Bgeei | ENSG00000086544, Expressed in lower esophagus mucosa and 209 other tissues |
ExpressionAtlasi | A0A024R0N8, baseline and differential |
Family and domain databases
Gene3Di | 1.10.510.50, 1 hit |
InterProi | View protein in InterPro IPR005522, IPK IPR038286, IPK_sf |
PANTHERi | PTHR12400, PTHR12400, 1 hit |
Pfami | View protein in Pfam PF03770, IPK, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A024R0N8_HUMAN | |
Accessioni | A0A024R0N8Primary (citable) accession number: A0A024R0N8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 9, 2014 |
Last sequence update: | July 9, 2014 | |
Last modified: | April 7, 2021 | |
This is version 57 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |