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Protein
Submitted name:

Synaptonemal complex protein 1, isoform CRA_b

Gene

SYCP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Synaptonemal complex protein 1, isoform CRA_bImported
Submitted name:
Testicular tissue protein Li 191Imported
Gene namesi
Name:SYCP1Imported
ORF Names:hCG_38460Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000198765.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000198765 Expressed in 54 organ(s), highest expression level in testis

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili124 – 147Sequence analysisAdd BLAST24
Coiled coili211 – 231Sequence analysisAdd BLAST21
Coiled coili243 – 316Sequence analysisAdd BLAST74
Coiled coili391 – 439Sequence analysisAdd BLAST49
Coiled coili499 – 663Sequence analysisAdd BLAST165
Coiled coili665 – 685Sequence analysisAdd BLAST21
Coiled coili739 – 798Sequence analysisAdd BLAST60

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IH3F Eukaryota
ENOG410XZPD LUCA
KOiK19533
OMAiWKFDSKA
OrthoDBiEOG091G0116

Family and domain databases

InterProiView protein in InterPro
IPR008827 SYCP1
IPR024835 SYCP1/2
PANTHERiPTHR15607 PTHR15607, 1 hit
PfamiView protein in Pfam
PF05483 SCP-1, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R0I2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKQKPFALF VPPRSSSSQV SAVKPQTLGG DSTFFKSFNK CTEDDFEFPF
60 70 80 90 100
AKTNLSKNGE NIDSDPALQK VNFLPVLEQV GNSDCHYQEG LKDSDLENSE
110 120 130 140 150
GLSRVYSKLY KEAEKIKKWK VSTEAELRQK ESKLQENRKI IEAQRKAIQE
160 170 180 190 200
LQFGNEKVSL KLEEGIQENK DLIKENNATR HLCNLLKETC ARSAEKTKKY
210 220 230 240 250
EYEREETRQV YMDLNNNIEK MITAFEELRV QAENSRLEMH FKLKEDYEKI
260 270 280 290 300
QHLEQEYKKE INDKEKQVSL LLIQITEKEN KMKDLTFLLE ESRDKVNQLE
310 320 330 340 350
EKTKLQSENL KQSIEKQHHL TKELEDIKVS LQRSVSTQKA LEEDLQIATK
360 370 380 390 400
TICQLTEEKE TQMEESNKAR AAHSFVVTEF ETTVCSLEEL LRTEQQRLEK
410 420 430 440 450
NEDQLKILTM ELQKKSSELE EMTKLTNNKE VELEELKKVL GEKETLLYEN
460 470 480 490 500
KQFEKIAEEL KGTEQELIGL LQAREKEVHD LEIQLTAITT SEQYYSKEVK
510 520 530 540 550
DLKTELENEK LKNTELTSHC NKLSLENKEL TQETSDMTLE LKNQQEDINN
560 570 580 590 600
NKKQEERMLK QIENLQETET QLRNELEYVR EELKQKRDEV KCKLDKSEEN
610 620 630 640 650
CNNLRKQVEN KNKYIEELQQ ENKALKKKGT AESKQLNVYE IKVNKLELEL
660 670 680 690 700
ESAKQKFGEI TDTYQKEIED KKISEENLLE EVEKAKVIAD EAVKLQKEID
710 720 730 740 750
KRCQHKIAEM VALMEKHKHQ YDKIIEERDS ELGLYKSKEQ EQSSLRASLE
760 770 780 790 800
IELSNLKAEL LSVKKQLEIE REEKEKLKRE AKENTATLKE KKDKKTQTFL
810 820 830 840 850
LETPEIYWKL DSKAVPSQTV SRNFTSVDHG ISKDKRDYLW TSAKNTLSTP
860 870 880 890 900
LPKAYTVKTP TKPKLQQREN LNIPIEESKK KRKMAFEFDI NSDSSETTDL
910 920 930 940 950
LSMVSEEETL KTLYRNNNPP ASHLCVKTPK KAPSSLTTPG STLKFGAIRK
960 970
MREDRWAVIA KMDRKKKLKE AEKLFV
Length:976
Mass (Da):114,192
Last modified:July 9, 2014 - v1
Checksum:i43058F1A4B7F57E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM005504 mRNA Translation: AEE61101.1
CH471122 Genomic DNA Translation: EAW56623.1
RefSeqiNP_001269470.1, NM_001282541.1
NP_003167.2, NM_003176.3
XP_006710922.1, XM_006710859.1
XP_016857673.1, XM_017002184.1
UniGeneiHs.112743

Genome annotation databases

GeneIDi6847
KEGGihsa:6847

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM005504 mRNA Translation: AEE61101.1
CH471122 Genomic DNA Translation: EAW56623.1
RefSeqiNP_001269470.1, NM_001282541.1
NP_003167.2, NM_003176.3
XP_006710922.1, XM_006710859.1
XP_016857673.1, XM_017002184.1
UniGeneiHs.112743

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6847
KEGGihsa:6847

Organism-specific databases

CTDi6847
EuPathDBiHostDB:ENSG00000198765.11

Phylogenomic databases

eggNOGiENOG410IH3F Eukaryota
ENOG410XZPD LUCA
KOiK19533
OMAiWKFDSKA
OrthoDBiEOG091G0116

Miscellaneous databases

ChiTaRSiSYCP1 human
GenomeRNAii6847

Gene expression databases

BgeeiENSG00000198765 Expressed in 54 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR008827 SYCP1
IPR024835 SYCP1/2
PANTHERiPTHR15607 PTHR15607, 1 hit
PfamiView protein in Pfam
PF05483 SCP-1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R0I2_HUMAN
AccessioniPrimary (citable) accession number: A0A024R0I2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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