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Protein
Submitted name:

G-protein signalling modulator 2 (AGS3-like, C. elegans), isoform CRA_a

Gene

GPSM2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
G-protein signalling modulator 2 (AGS3-like, C. elegans), isoform CRA_aImported
Gene namesi
Name:GPSM2Imported
ORF Names:hCG_39913Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000121957.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000121957 Expressed in 222 organ(s), highest expression level in tibia

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 135TPR_REGIONInterPro annotationAdd BLAST74
Repeati62 – 95TPRPROSITE-ProRule annotationAdd BLAST34
Repeati102 – 135TPRPROSITE-ProRule annotationAdd BLAST34
Domaini202 – 355TPR_REGIONInterPro annotationAdd BLAST154
Repeati202 – 235TPRPROSITE-ProRule annotationAdd BLAST34
Repeati242 – 275TPRPROSITE-ProRule annotationAdd BLAST34
Repeati282 – 315TPRPROSITE-ProRule annotationAdd BLAST34
Repeati322 – 355TPRPROSITE-ProRule annotationAdd BLAST34

Keywords - Domaini

TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1130 Eukaryota
ENOG410XP6N LUCA
KOiK15837
OMAiMLKTPSV
OrthoDBiEOG091G04C9

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR003109 GoLoco_motif
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF02188 GoLoco, 4 hits
PF13176 TPR_7, 2 hits
PF13181 TPR_8, 1 hit
SMARTiView protein in SMART
SM00390 GoLoco, 4 hits
SM00028 TPR, 7 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50877 GOLOCO, 4 hits
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 2 hits

Sequencei

Sequence statusi: Complete.

A0A024R0F8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEENLISMRE DHSFHVRYRM EASCLELALE GERLCKSGDC RAGVSFFEAA
60 70 80 90 100
VQVGTEDLKT LSAIYSQLGN AYFYLHDYAK ALEYHHHDLT LARTIGDQLG
110 120 130 140 150
EAKASGNLGN TLKVLGNFDE AIVCCQRHLD ISRELNDKVG EARALYNLGN
160 170 180 190 200
VYHAKGKSFG CPGPQDVGEF PEEVRDALQA AVDFYEENLS LVTALGDRAA
210 220 230 240 250
QGRAFGNLGN THYLLGNFRD AVIAHEQRLL IAKEFGDKAA ERRAYSNLGN
260 270 280 290 300
AYIFLGEFET ASEYYKKTLL LARQLKDRAV EAQSCYSLGN TYTLLQDYEK
310 320 330 340 350
AIDYHLKHLA IAQELNDRIG EGRACWSLGN AYTALGNHDQ AMHFAEKHLE
360 370 380 390 400
ISREVGDKSG ELTARLNLSD LQMVLGLSYS TNNSIMSENT EIDSSLNGVR
410 420 430 440 450
PKLGRRHSME NMELMKLTPE KVQNWNSEIL AKQKPLIAKP SAKLLFVNRL
460 470 480 490 500
KGKKYKTNSS TKVLQDASNS IDHRIPNSQR KISADTIGDE GFFDLLSRFQ
510 520 530 540 550
SNRMDDQRCC LQEKNCHTAS TTTSSTPPKM MLKTSSVPVV SPNTDEFLDL
560 570 580 590 600
LASSQSRRLD DQRASFSNLP GLRLTQNSQS VLSHLMTNDN KEADEDFFDI
610 620 630 640 650
LVKCQGSRLD DQRCAPPPAT TKGPTVPDED FFSLILRSQG KRMDEQRVLL
660 670 680
QRDQNRDTDF GLKDFLQNNA LLEFKNSGKK SADH
Length:684
Mass (Da):76,662
Last modified:July 9, 2014 - v1
Checksum:iD007A4765F57CB90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471122 Genomic DNA Translation: EAW56341.1
CH471122 Genomic DNA Translation: EAW56342.1
CH471122 Genomic DNA Translation: EAW56343.1
CH471122 Genomic DNA Translation: EAW56344.1
RefSeqiNP_001307967.1, NM_001321038.1
NP_001307968.1, NM_001321039.1
NP_037428.3, NM_013296.4
XP_011539603.1, XM_011541301.2
XP_011539604.1, XM_011541302.2
XP_016856586.1, XM_017001097.1
XP_016856587.1, XM_017001098.1
UniGeneiHs.584901
Hs.658489

Genome annotation databases

GeneIDi29899
KEGGihsa:29899

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471122 Genomic DNA Translation: EAW56341.1
CH471122 Genomic DNA Translation: EAW56342.1
CH471122 Genomic DNA Translation: EAW56343.1
CH471122 Genomic DNA Translation: EAW56344.1
RefSeqiNP_001307967.1, NM_001321038.1
NP_001307968.1, NM_001321039.1
NP_037428.3, NM_013296.4
XP_011539603.1, XM_011541301.2
XP_011539604.1, XM_011541302.2
XP_016856586.1, XM_017001097.1
XP_016856587.1, XM_017001098.1
UniGeneiHs.584901
Hs.658489

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi29899
KEGGihsa:29899

Organism-specific databases

CTDi29899
EuPathDBiHostDB:ENSG00000121957.12

Phylogenomic databases

eggNOGiKOG1130 Eukaryota
ENOG410XP6N LUCA
KOiK15837
OMAiMLKTPSV
OrthoDBiEOG091G04C9

Miscellaneous databases

GenomeRNAii29899

Gene expression databases

BgeeiENSG00000121957 Expressed in 222 organ(s), highest expression level in tibia

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR003109 GoLoco_motif
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF02188 GoLoco, 4 hits
PF13176 TPR_7, 2 hits
PF13181 TPR_8, 1 hit
SMARTiView protein in SMART
SM00390 GoLoco, 4 hits
SM00028 TPR, 7 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50877 GOLOCO, 4 hits
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R0F8_HUMAN
AccessioniPrimary (citable) accession number: A0A024R0F8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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