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Protein
Submitted name:

Ras responsive element binding protein 1, isoform CRA_a

Gene

RREB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Ras responsive element binding protein 1, isoform CRA_aImported
Gene namesi
Name:RREB1Imported
ORF Names:hCG_15864Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000124782.19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000124782 Expressed in 230 organ(s), highest expression level in epithelium of mammary gland

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 93C2H2-typeInterPro annotationAdd BLAST28
Domaini97 – 124C2H2-typeInterPro annotationAdd BLAST28
Domaini125 – 152C2H2-typeInterPro annotationAdd BLAST28
Domaini208 – 235C2H2-typeInterPro annotationAdd BLAST28
Domaini316 – 343C2H2-typeInterPro annotationAdd BLAST28
Domaini643 – 670C2H2-typeInterPro annotationAdd BLAST28
Domaini671 – 698C2H2-typeInterPro annotationAdd BLAST28
Domaini699 – 722C2H2-typeInterPro annotationAdd BLAST24
Domaini753 – 780C2H2-typeInterPro annotationAdd BLAST28
Domaini790 – 820C2H2-typeInterPro annotationAdd BLAST31
Domaini1246 – 1273C2H2-typeInterPro annotationAdd BLAST28
Domaini1393 – 1420C2H2-typeInterPro annotationAdd BLAST28
Domaini1512 – 1539C2H2-typeInterPro annotationAdd BLAST28
Domaini1540 – 1567C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

KOiK20210

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits

Sequencei

Sequence statusi: Complete.

A0A024QZU8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSSSPAGLE GSDLSSINTM MSAVMSVGKV TENGGSPQGI KSPSKPPGPN
60 70 80 90 100
RIGRRNQETK EEKSSYNCPL CEKICTTQHQ LTMHIRQHNT DTGGADHSCS
110 120 130 140 150
ICGKSLSSAS SLDRHMLVHS GERPYKCTVC GQSFTTNGNM HRHMKIHEKD
160 170 180 190 200
PNSATATAPP SPLKRRRLSS KRKLSHDAES EREDPAPAKK MVEDGQSGDL
210 220 230 240 250
EKKADEVFHC PVCFKEFVCK YGLETHMETH SDNPLRCDIC CVTFRTHRGL
260 270 280 290 300
LRHNALVHKQ LPRDAMGRPF IQNNPSIPAG FHDLGFTDFS CRKFPRISQA
310 320 330 340 350
WCETNLRRCI SEQHRFVCDT CDKAFPMLCS LALHKQTHVA ADQGQEKPQA
360 370 380 390 400
TPLPGDALDQ KGFLALLGLQ HTKDVRPAPA EEPLPDDNQA IQLQTLKCQL
410 420 430 440 450
PQDPGCTNLL SLSPFEAASL GGSLTVLPAT KDSIKHLSLQ PFQKGFIIQP
460 470 480 490 500
DSSIVVKPIS GESAIELADI QQILKMAASA PPQISLPPFS KAPAAPLQAI
510 520 530 540 550
FKHMPPLKPK PLVTPRTVVA TSTPPPLINA QQASPGCISP SLPPPPLKLL
560 570 580 590 600
KGSVEAASNA HLLQSKSGTQ PHAATRLSLQ QPRAELPGQP EMKTQLEQDS
610 620 630 640 650
IIEALLPLSM EAKIKQEITE GELKAFMTAP GGKKTPAMRK VLYPCRFCNQ
660 670 680 690 700
VFAFSGVLRA HVRSHLGISP YQCNICDYIA ADKAALIRHL RTHSGERPYI
710 720 730 740 750
CKICHYPFTV KANCERHLRK KHLKATRKDI EKNIEYVSSS AAELVDAFCA
760 770 780 790 800
PDTVCRLCGE DLKHYRALRI HMRTHCGRGL GGGHKGRKPF ECKECSAAFA
810 820 830 840 850
AKRNCIHHIL KQHLHVPEQD IESYVLAADG LGPAEAPAAE ASGRGEDSGC
860 870 880 890 900
AALGDCKPLT AFLEPQNGFL HRGPTQPPPP HVSIKLEPAS SFAVDFNEPL
910 920 930 940 950
DFSQKGLALV QVKQENISFL SPSSLVPYDC SMEPIDLSIP KNFRKGDKDL
960 970 980 990 1000
ATPSEAKKPE EEAGSSEQPS PCPAPGPSLP VTLGPSGILE SPMAPAPAAT
1010 1020 1030 1040 1050
PEPPAQPLQG PVQLAVPIYS SALVSSPPLV GSSALLSGTA LLRPLRPKPP
1060 1070 1080 1090 1100
LLLPKPPVTE ELPPLASIAQ IISSVSSAPT LLKTKVADPG PASTGSNTTA
1110 1120 1130 1140 1150
SDSLGGSVPK AATTATPAAT TSPKESSEPP APASSPEAAS PTEQGPAGTS
1160 1170 1180 1190 1200
KKRGRKRGMR SRPRANSGGV DLDSSGEFAS IEKMLATTDT NKFSPFLQTA
1210 1220 1230 1240 1250
EDNTQDEVAG APADHHGPSD EEQGSPPEDK LLRAKRNSYT NCLQKITCPH
1260 1270 1280 1290 1300
CPRVFPWASS LQRHMLTHTD SQSDAETAAA AGEVLDLTSR DREQPSEGAT
1310 1320 1330 1340 1350
ELRQVAGDAP VEQATAETAS PVHREEHGRG ESHEPEEEHG TEESTGDADG
1360 1370 1380 1390 1400
AEEDASSNQS LDLDFATKLM DFKLAEGDGE AGAGGAASQE QKLACDTCGK
1410 1420 1430 1440 1450
SFKFLGTLSR HRKAHGRQEP KDEKGDGAST AEEGPQPAPE QEEKPPETPA
1460 1470 1480 1490 1500
EVVESAPGAG EAPAEKLAEE TEGPSDGESA AEKRSSEKSD DDKKPKTDSP
1510 1520 1530 1540 1550
KSVASKADKR KKVCSVCNKR FWSLQDLTRH MRSHTGERPY KCQTCERTFT
1560 1570 1580 1590 1600
LKHSLVRHQR IHQKARHAKH HGKDSDKEER GEEDSENEST HSGNNAVSEN
1610 1620 1630 1640 1650
EAELAPNASN HMAVTRSRKE GLASATKDCS HREEKVTAGW PSEPGQGDLN
1660 1670 1680
PESPAALGQD LLEPRSKRPA HPILATADGA SQLVGME
Length:1,687
Mass (Da):181,420
Last modified:July 9, 2014 - v1
Checksum:i33B5755B0243C64F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471087 Genomic DNA Translation: EAW55198.1
CH471087 Genomic DNA Translation: EAW55199.1
CH471087 Genomic DNA Translation: EAW55200.1
RefSeqiNP_001003698.1, NM_001003698.3
NP_001161816.1, NM_001168344.1
UniGeneiHs.298248

Genome annotation databases

GeneIDi6239
KEGGihsa:6239

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471087 Genomic DNA Translation: EAW55198.1
CH471087 Genomic DNA Translation: EAW55199.1
CH471087 Genomic DNA Translation: EAW55200.1
RefSeqiNP_001003698.1, NM_001003698.3
NP_001161816.1, NM_001168344.1
UniGeneiHs.298248

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6239
KEGGihsa:6239

Organism-specific databases

CTDi6239
EuPathDBiHostDB:ENSG00000124782.19

Phylogenomic databases

KOiK20210

Miscellaneous databases

ChiTaRSiRREB1 human
GenomeRNAii6239

Gene expression databases

BgeeiENSG00000124782 Expressed in 230 organ(s), highest expression level in epithelium of mammary gland

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024QZU8_HUMAN
AccessioniPrimary (citable) accession number: A0A024QZU8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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