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Protein
Submitted name:

Rho-related BTB domain containing 1, isoform CRA_c

Gene

RHOBTB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Rho-related BTB domain containing 1, isoform CRA_cImported
Gene namesi
Name:RHOBTB1Imported
ORF Names:hCG_40241Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000072422.16

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSG00000072422 Expressed in 221 organ(s), highest expression level in placenta

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini266 – 427BTBInterPro annotationAdd BLAST162
Domaini485 – 552BTBInterPro annotationAdd BLAST68

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
KOiK07868
OMAiEMQVNPV
OrthoDBiEOG091G03I3

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR027417 P-loop_NTPase
IPR011333 SKP1/BTB/POZ_sf
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00651 BTB, 2 hits
PF00071 Ras, 1 hit
SMARTiView protein in SMART
SM00225 BTB, 2 hits
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54695 SSF54695, 2 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 2 hits
PS51420 RHO, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024QZL4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDADMDYERP NVETIKCVVV GDNAVGKTRL ICARACNTTL TQYQLLATHV
60 70 80 90 100
PTVWAIDQYR VCQEVLERSR DVVDEVSVSL RLWDTFGDHH KDRRFAYGRS
110 120 130 140 150
DVVVLCFSIA NPNSLNHVKS MWYPEIKHFC PRTPVILVGC QLDLRYADLE
160 170 180 190 200
AVNRARRPLA RPIKRGDILP PEKGREVAKE LGLPYYETSV FDQFGIKDVF
210 220 230 240 250
DNAIRAALIS RRHLQFWKSH LKKVQKPLLQ APFLPPKAPP PVIKIPECPS
260 270 280 290 300
MGTNEAACLL DNPLCADVLF ILQDQEHIFA HRIYLATSSS KFYDLFLMEC
310 320 330 340 350
EESPNGSEGA CEKEKQSRDF QGRILSVDPE EEREEGPPRI PQADQWKSSN
360 370 380 390 400
KSLVEALGLE AEGAVPETQT LTGWSKGFIG MHREMQVNPI SKRMGPMTVV
410 420 430 440 450
RMDASVQPGP FRTLLQFLYT GQLDEKEKDL VGLAQIAEVL EMFDLRMMVE
460 470 480 490 500
NIMNKEAFMN QEITKAFHVR KANRIKECLS KGTFSDVTFK LDDGAISAHK
510 520 530 540 550
PLLICSCEWM AAMFGGSFVE SANSEVYLPN INKISMQAVL DYLYTKQLSP
560 570 580 590 600
NLDLDPLELI ALANRFCLPH LVALAEQHAV QELTKAATSG VGIDGEVLSY
610 620 630 640 650
LELAQFHNAH QLAAWCLHHI CTNYNSVCSK FRKEIKSKSA DNQEYFERHR
660 670 680 690
WPPVWYLKEE DHYQRVKRER EKEDIALNKH RSRRKWCFWN SSPAVA
Length:696
Mass (Da):79,417
Last modified:July 9, 2014 - v1
Checksum:i41ECB4425CD32A1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471083 Genomic DNA Translation: EAW54213.1
CH471083 Genomic DNA Translation: EAW54215.1
CH471083 Genomic DNA Translation: EAW54216.1
CH471083 Genomic DNA Translation: EAW54217.1
RefSeqiNP_001229288.1, NM_001242359.1
NP_055651.1, NM_014836.4
XP_006718147.1, XM_006718084.1
XP_006718148.1, XM_006718085.1
XP_011538726.1, XM_011540424.1
XP_016872489.1, XM_017017000.1
XP_016872490.1, XM_017017001.1
UniGeneiHs.737374

Genome annotation databases

GeneIDi9886
KEGGihsa:9886

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471083 Genomic DNA Translation: EAW54213.1
CH471083 Genomic DNA Translation: EAW54215.1
CH471083 Genomic DNA Translation: EAW54216.1
CH471083 Genomic DNA Translation: EAW54217.1
RefSeqiNP_001229288.1, NM_001242359.1
NP_055651.1, NM_014836.4
XP_006718147.1, XM_006718084.1
XP_006718148.1, XM_006718085.1
XP_011538726.1, XM_011540424.1
XP_016872489.1, XM_017017000.1
XP_016872490.1, XM_017017001.1
UniGeneiHs.737374

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9886
KEGGihsa:9886

Organism-specific databases

CTDi9886
EuPathDBiHostDB:ENSG00000072422.16

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
KOiK07868
OMAiEMQVNPV
OrthoDBiEOG091G03I3

Miscellaneous databases

ChiTaRSiRHOBTB1 human
GenomeRNAii9886

Gene expression databases

BgeeiENSG00000072422 Expressed in 221 organ(s), highest expression level in placenta

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR027417 P-loop_NTPase
IPR011333 SKP1/BTB/POZ_sf
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00651 BTB, 2 hits
PF00071 Ras, 1 hit
SMARTiView protein in SMART
SM00225 BTB, 2 hits
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54695 SSF54695, 2 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 2 hits
PS51420 RHO, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024QZL4_HUMAN
AccessioniPrimary (citable) accession number: A0A024QZL4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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