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Protein
Submitted name:

ST3 beta-galactoside alpha-2,3-sialyltransferase 2, isoform CRA_a

Gene

ST3GAL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei116SubstrateUniRule annotation1
Binding sitei157SubstrateUniRule annotation1
Binding sitei180SubstrateUniRule annotation1
Binding sitei240SubstrateUniRule annotation1
Binding sitei276SubstrateUniRule annotation1
Binding sitei280Substrate; via amide nitrogenUniRule annotation1
Binding sitei300Substrate; via amide nitrogenUniRule annotation1
Binding sitei309SubstrateUniRule annotation1
Binding sitei326SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseSAAS annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
ST3 beta-galactoside alpha-2,3-sialyltransferase 2, isoform CRA_aImported
Gene namesi
Name:ST3GAL2Imported
ORF Names:hCG_32368Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000157350.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 26HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi152 ↔ 291UniRule annotation

Expressioni

Gene expression databases

BgeeiENSG00000157350 Expressed in 209 organ(s), highest expression level in blood

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
KOiK03368
OMAiCACRRCM
OrthoDBiEOG091G08DE

Family and domain databases

Gene3Di3.90.1480.20, 1 hit
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
IPR012163 Sialyl_trans
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit
PIRSFiPIRSF005557 Sialyl_trans, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024QZA4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKCSLRVWFL SVAFLLVFIM SLLFTYSHHS MATLPYLDSG ALDGTHRVKL
60 70 80 90 100
VPGYAGLQRL SKERLSGKSC ACRRCMGDAG ASDWFDSHFD GNISPVWTRE
110 120 130 140 150
NMDLPPDVQR WWMMLQPQFK SHNTNEVLEK LFQIVPGENP YRFRDPHQCR
160 170 180 190 200
RCAVVGNSGN LRGSGYGQDV DGHNFIMRMN QAPTVGFEQD VGSRTTHHFM
210 220 230 240 250
YPESAKNLPA NVSFVLVPFK VLDLLWIASA LSTGQIRFTY APVKSFLRVD
260 270 280 290 300
KEKVQIYNPA FFKYIHDRWT EHHGRYPSTG MLVLFFALHV CDEVNVYGFG
310 320 330 340 350
ADSRGNWHHY WENNRYAGEF RKTGVHDADF EAHIIDMLAK ASKIEVYRGN
Length:350
Mass (Da):40,173
Last modified:July 9, 2014 - v1
Checksum:iE7E40CF26D9CB725
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471241 Genomic DNA Translation: EAW51818.1
CH471241 Genomic DNA Translation: EAW51819.1
CH471241 Genomic DNA Translation: EAW51820.1
CH471241 Genomic DNA Translation: EAW51821.1
RefSeqiNP_008858.1, NM_006927.3
UniGeneiHs.368611

Genome annotation databases

GeneIDi6483
KEGGihsa:6483

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471241 Genomic DNA Translation: EAW51818.1
CH471241 Genomic DNA Translation: EAW51819.1
CH471241 Genomic DNA Translation: EAW51820.1
CH471241 Genomic DNA Translation: EAW51821.1
RefSeqiNP_008858.1, NM_006927.3
UniGeneiHs.368611

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6483
KEGGihsa:6483

Organism-specific databases

CTDi6483
EuPathDBiHostDB:ENSG00000157350.12

Phylogenomic databases

eggNOGiKOG2692 Eukaryota
ENOG410XT8P LUCA
KOiK03368
OMAiCACRRCM
OrthoDBiEOG091G08DE

Miscellaneous databases

ChiTaRSiST3GAL2 human
GenomeRNAii6483

Gene expression databases

BgeeiENSG00000157350 Expressed in 209 organ(s), highest expression level in blood

Family and domain databases

Gene3Di3.90.1480.20, 1 hit
InterProiView protein in InterPro
IPR001675 Glyco_trans_29
IPR038578 GT29-like_sf
IPR012163 Sialyl_trans
PfamiView protein in Pfam
PF00777 Glyco_transf_29, 1 hit
PIRSFiPIRSF005557 Sialyl_trans, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024QZA4_HUMAN
AccessioniPrimary (citable) accession number: A0A024QZA4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 10, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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