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Protein
Submitted name:

Wiskott-Aldrich syndrome (Eczema-thrombocytopenia), isoform CRA_a

Gene

WAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Wiskott-Aldrich syndrome (Eczema-thrombocytopenia), isoform CRA_aImported
Gene namesi
Name:WASImported
ORF Names:hCG_19822Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000015285.10

Subcellular locationi

PTM / Processingi

Proteomic databases

PRIDEiA0A024QYX8

Expressioni

Gene expression databases

BgeeiENSG00000015285
ExpressionAtlasiA0A024QYX8 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA0A024QYX8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 148WH1InterPro annotationAdd BLAST110
Domaini238 – 251CRIBInterPro annotationAdd BLAST14
Domaini430 – 447WH2InterPro annotationAdd BLAST18

Phylogenomic databases

eggNOGiKOG3671 Eukaryota
ENOG4111M1J LUCA
KOiK05747
OMAiEMRRQEP
OrthoDBiEOG091G0VCD

Family and domain databases

CDDicd00132 CRIB, 1 hit
cd01205 EVH1_WASP-like, 1 hit
Gene3Di2.30.29.30, 1 hit
3.90.810.10, 2 hits
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011993 PH-like_dom_sf
IPR027641 WASP
IPR011026 WASP_C
IPR033927 WASPfam_EVH1
IPR000697 WH1/EVH1_dom
IPR003124 WH2_dom
PANTHERiPTHR23202:SF35 PTHR23202:SF35, 1 hit
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00568 WH1, 1 hit
PF02205 WH2, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SM00461 WH1, 1 hit
SM00246 WH2, 1 hit
SUPFAMiSSF47912 SSF47912, 2 hits
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS50229 WH1, 1 hit
PS51082 WH2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024QYX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGGPMGGRP GGRGAPAVQQ NIPSTLLQDH ENQRLFEMLG RKCLTLATAV
60 70 80 90 100
VQLYLALPPG AEHWTKEHCG AVCFVKDNPQ KSYFIRLYGL QAGRLLWEQE
110 120 130 140 150
LYSQLVYSTP TPFFHTFAGD DCQAGLNFAD EDEAQAFRAL VQEKIQKRNQ
160 170 180 190 200
RQSGDRRQLP PPPTPANEER RGGLPPLPLH PGGDQGGPPV GPLSLGLATV
210 220 230 240 250
DIQNPDITSS RYRGLPAPGP SPADKKRSGK KKISKADIGA PSGFKHVSHV
260 270 280 290 300
GWDPQNGFDV NNLDPDLRSL FSRAGISEAQ LTDAETSKLI YDFIEDQGGL
310 320 330 340 350
EAVRQEMRRQ EPLPPPPPPS RGGNQLPRPP IVGGNKGRSG PLPPVPLGIA
360 370 380 390 400
PPPPTPRGPP PPGRGGPPPP PPPATGRSGP LPPPPPGAGG PPMPPPPPPP
410 420 430 440 450
PPPPSSGNGP APPPLPPALV PAGGLAPGGG RGALLDQIRQ GIQLNKTPGA
460 470 480 490 500
PESSALQPPP QSSEGLVGAL MHVMQKRSRA IHSSDEGEDQ AGDEDEDDEW

DD
Length:502
Mass (Da):52,913
Last modified:July 9, 2014 - v1
Checksum:i7228428672B7CB78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471224 Genomic DNA Translation: EAW50758.1
CH471224 Genomic DNA Translation: EAW50759.1
RefSeqiNP_000368.1, NM_000377.2
UniGeneiHs.2157

Genome annotation databases

GeneIDi7454
KEGGihsa:7454

Similar proteinsi

Entry informationi

Entry nameiA0A024QYX8_HUMAN
AccessioniPrimary (citable) accession number: A0A024QYX8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: July 18, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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