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Protein

Nucleoside permease

Gene

nupC

Organism
Escherichia coli D6-113.11
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside permeaseUniRule annotation
Gene namesi
Name:nupCImported
ORF Names:PGA_04177Imported
OrganismiEscherichia coli D6-113.11Imported
Taxonomic identifieri1400022 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 23HelicalUniRule annotationAdd BLAST18
Transmembranei30 – 48HelicalUniRule annotationAdd BLAST19
Transmembranei87 – 108HelicalUniRule annotationAdd BLAST22
Transmembranei193 – 212HelicalUniRule annotationAdd BLAST20
Transmembranei242 – 271HelicalUniRule annotationAdd BLAST30
Transmembranei277 – 298HelicalUniRule annotationAdd BLAST22
Transmembranei341 – 361HelicalUniRule annotationAdd BLAST21
Transmembranei381 – 399HelicalUniRule annotationAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliA0A024KXE6
SMRiA0A024KXE6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 82Nucleos_tra2_NInterPro annotationAdd BLAST73
Domaini92 – 189GateInterPro annotationAdd BLAST98
Domaini193 – 398Nucleos_tra2_CInterPro annotationAdd BLAST206

Sequence similaritiesi

Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR008276 C_nuclsd_transpt
IPR018270 C_nuclsd_transpt_met_bac
IPR011657 CNT_C_dom
IPR002668 CNT_N_dom
IPR011642 Gate_dom
PANTHERiPTHR10590 PTHR10590, 1 hit
PfamiView protein in Pfam
PF07670 Gate, 1 hit
PF07662 Nucleos_tra2_C, 1 hit
PF01773 Nucleos_tra2_N, 1 hit
TIGRFAMsiTIGR00804 nupC, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024KXE6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRVLHFVLA LAVVAILALL VSSDRKKIRI RYVIQLLVIE VLLAWFFLNS
60 70 80 90 100
DVGLGFVKGF SEMFEKLLGF ANEGTNFVFG SMNDQGLAFF FLKVLCPIVF
110 120 130 140 150
ISALIGILQH IRVLPVIIRA IGFLLSKVNG MGKLESFNAV SSLILGQSEN
160 170 180 190 200
FIAYKDILGK ISRNRMYTMA ATAMSTVSMS IVGAYMTMLE PKYVVAALVL
210 220 230 240 250
NMFSTFIVLS LINPYRVDAS EENIQMSNLH EGQSFFEMLG EYILAGFKVA
260 270 280 290 300
IIVAAMLIGF IALIAALNAL FATVTGWFGY SISFQGILGY IFYPIAWVMG
310 320 330 340 350
VPSSEALQVG SIMATKLVSN EFVAMMDLQK IASTLSPRAE GIISVFLVSF
360 370 380 390 400
ANFSSIGIIA GAVKGLNEEQ GNVVSRFGLK LVYGSTLVSV LSASIAALVL
Length:400
Mass (Da):43,476
Last modified:July 9, 2014 - v1
Checksum:i1EA1DE138C4351CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HG977190 Genomic DNA Translation: CDU37062.1
RefSeqiWP_000376337.1, NZ_HG977190.1

Genome annotation databases

EnsemblBacteriaiCDU37062; CDU37062; PGA_04177

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HG977190 Genomic DNA Translation: CDU37062.1
RefSeqiWP_000376337.1, NZ_HG977190.1

3D structure databases

ProteinModelPortaliA0A024KXE6
SMRiA0A024KXE6
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCDU37062; CDU37062; PGA_04177

Family and domain databases

InterProiView protein in InterPro
IPR008276 C_nuclsd_transpt
IPR018270 C_nuclsd_transpt_met_bac
IPR011657 CNT_C_dom
IPR002668 CNT_N_dom
IPR011642 Gate_dom
PANTHERiPTHR10590 PTHR10590, 1 hit
PfamiView protein in Pfam
PF07670 Gate, 1 hit
PF07662 Nucleos_tra2_C, 1 hit
PF01773 Nucleos_tra2_N, 1 hit
TIGRFAMsiTIGR00804 nupC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024KXE6_ECOLX
AccessioniPrimary (citable) accession number: A0A024KXE6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 7, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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